1-BOC-6-AMINO-INDAZOLE

Product Name: 1-BOC-6-AMINO-INDAZOLE
CAS No.: 219503-81-8
Chemical Name: 1-BOC-6-AMINO-INDAZOLE
Synonyms: 1-BOC-6-AMINO-INDAZOLE;1-Boc-1H-indazol-6-amine;6-Amino-1-Boc-1H-indazole;6-Amino-1H-indazole, N1-BOC;1-Boc-6-amino-1H-indazole,97%;6-Amino-1H-indazole, N1-BOC protected;6-AMINO-1-N-TERT-BUTOXYCARBONYL-1H-INDAZOLE;tert-butyl 6-amino-1H-indazole-1-carboxylate;6-AMINO-INDAZOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;6-AMINO-1H-INDAZOLE-1-CARBOXYLIC ACID, 1,1 DIMETHYL ETHYL ESTER
CBNumber: CB5717565
Molecular Formula: C12H15N3O2
Formula Weight: 233.27
MOL File: 219503-81-8.mol

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1-BOC-6-AMINO-INDAZOLE Property

Melting point:: 171-172℃
Boiling point:: 395.3±34.0 °C(Predicted)
Density: 1.24±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 2.52±0.10(Predicted)
form: powder
color: Yellow
Water Solubility: Slightlysoluble in water.

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: B415625
Product name: tert-Butyl6-Amino-1H-indazole-1-carboxylate
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: OR17051
Product name: 6-Amino-1H-indazole,N1-BOCprotected
Packaging: 100mg
Price: $24
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-1-38
Product name: 1-Boc-1H-indazol-6-amine
Purity: 98%
Packaging: 100mg
Price: $29
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB51014
Product name: 1-Boc-6-amino-indazole
Packaging: 25mg
Price: $40
Updated: 2021/12/16

Apolloscientific

Product number: OR17051
Product name: 6-Amino-1H-indazole,N1-BOCprotected
Packaging: 250mg
Price: $48
Updated: 2021/12/16

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1-BOC-6-AMINO-INDAZOLE Chemical Properties,Usage,Production

Uses

Used in the synthesis of chiral molecules.

Synthesis

219503-74-9

219503-81-8

Step B: Preparation of tert-butyl 6-amino-1H-indazole-1-carboxylate: To a solution of tert-butyl 6-nitro-1H-indazole-1-carboxylate (0.88 g, 3.34 mmol) in methanol (20 mL) was added 10% Pd/C catalyst (0.355 g, 0.334 mmol). After displacing the air in the reaction system with nitrogen, the hydrogenation reaction was carried out under hydrogen (30 psi) atmosphere for 2 hours. After completion of the reaction, the reaction mixture was filtered through GF/F filter paper and the filtrate was concentrated to afford the target product tert-butyl 6-amino-1H-indazole-1-carboxylate (0.76 g, 98% yield). Mass spectrometry analysis (APCI-positive ion mode) showed [M+1]+ peak of 233.8.

References

[1] Patent: US2010/63066, 2010, A1. Location in patent: Page/Page column 35
[2] Journal of Medicinal Chemistry, 2002, vol. 45, # 4, p. 944 - 954
[3] Patent: US6372759, 2002, B1
[4] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 13, p. 3821 - 3830
[5] Asian Journal of Chemistry, 2014, vol. 26, # 22, p. 7539 - 7543

1-BOC-6-AMINO-INDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-BOC-6-AMINO-INDAZOLE Suppliers

China 67 India 2 United Kingdom 4 United States 16 Global 89

3B Pharmachem (Wuhan) International Co.,Ltd.

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219503-81-8, 1-BOC-6-AMINO-INDAZOLERelated Search:

1-BOC-6-BROMO-INDAZOLE 1H-Indazole-3-carboxylic acid, 6-broMo-, 1,1-diMethylethyl ester 6-AMINO-3-(4-METHYL-PIPERAZIN-1-YLMETHYL)-INDAZOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 6-AMINO-3-MORPHOLIN-4-YLMETHYL-INDAZOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 6-CYANOAMINO-INDAZOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 6-AMINO-3-DIETHYLAMINOMETHYL-INDAZOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 6-AMINO-3-PYRROLIDIN-1-YLMETHYL-INDAZOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 6-AMINO-3-AZETIDIN-1-YLMETHYL-INDAZOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 1-BOC-6-AMINO-INDAZOLE

6-AMINO-1H-INDAZOLE-1-CARBOXYLIC ACID, 1,1 DIMETHYL ETHYL ESTER

6-AMINO-1-N-TERT-BUTOXYCARBONYL-1H-INDAZOLE

6-AMINO-INDAZOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

1-BOC-6-AMINO-INDAZOLE

tert-butyl 6-amino-1H-indazole-1-carboxylate

6-Amino-1H-indazole, N1-BOC protected

1H-Indazole-1-carboxylic acid, 6-aMino-, 1,1-diMethylethyl ester

6-Amino-1H-indazole, N1-BOC

tert-Butyl 6-amino-1H-indazole-1-carboxylate, 6-Amino-1-(tert-butoxycarbonyl)-1H-indazole

1-Boc-1H-indazol-6-amine

1-Boc-6-amino-1H-indazole,97%

6-Amino-1-Boc-1H-indazole

219503-81-8

Indazoles

Building Blocks

Indazole