ChemicalBook > CAS DataBase List > MSA-2

MSA-2

Product Name
MSA-2
CAS No.
129425-81-6
Chemical Name
MSA-2
Synonyms
MSA-2;4-(5,6-dimethoxy-1-benzothiophen-2-yl)-4-oxobut;5,6-Dimethoxy-γ-oxobenzo[b]thiophene-2-butanoic acid;Benzo[b]thiophene-2-butanoic acid, 5,6-dimethoxy-γ-oxo-;4-(5,6-Dimethoxybenzo[b]thiophen-2-yl)-4-oxobutanoic acid;4- (5,6-Dimethoxybenzo [b] thiophen-2-yl) -4-oxobutyric acid;interferon-β,Inhibitor,TMEM173,ERIS,MPYS,immunity,secretion,tumor,Stimulator of Interferon Genes,MSA 2,MC38,STING,MSA2,TNF-α,MITA,MSA-2,inhibit
CBNumber
CB57244028
Molecular Formula
C14H14O5S
Formula Weight
294.32
MOL File
129425-81-6.mol
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MSA-2 Property

Boiling point:
509.3±50.0 °C(Predicted)
Density 
1.336±0.06 g/cm3(Predicted)
storage temp. 
4°C, protect from light
solubility 
DMSO: 125 mg/mL (424.71 mM)
form 
A crystalline solid
pka
4.35±0.17(Predicted)
color 
Light yellow to brown
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Tocris
Product number
7353
Product name
MSA2
Purity
≥98%(HPLC)
Packaging
50
Price
$569
Updated
2021/12/16
ChemScene
Product number
CS-0135308
Product name
MSA-2
Purity
98.79%
Packaging
10mg
Price
$580
Updated
2021/12/16
Adipogen Life Sciences
Product number
AG-CR1-0164-M005
Product name
MSA-2
Purity
≥98%
Packaging
5mg
Price
$80
Updated
2021/12/16
ChemScene
Product number
CS-0135308
Product name
MSA-2
Purity
98.79%
Packaging
5mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-0135308
Product name
MSA-2
Purity
98.79%
Packaging
25mg
Price
$1100
Updated
2021/12/16
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MSA-2 Chemical Properties,Usage,Production

Description

MSA-2 was identified in a phenotypic screen for a chemical inducer of interferon beta secretion. In cell-free assays, MSA-2 binds to human and mouse STING. In tumor-bearing mice, MSA-2 induced elevated interferon-beta in plasma and tumors through two routes of administration.

Uses

MSA-2 is an oral non-nucleotide STING agonist with EC50 of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively.

storage

Store at -20°C

MSA-2 Preparation Products And Raw materials

Raw materials

Preparation Products

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MSA-2 Suppliers

China 68 United States 6 USA 1 Global 75
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129425-81-6, MSA-2Related Search:


  • MSA-2
  • Benzo[b]thiophene-2-butanoic acid, 5,6-dimethoxy-γ-oxo-
  • 4-(5,6-Dimethoxybenzo[b]thiophen-2-yl)-4-oxobutanoic acid
  • 5,6-Dimethoxy-γ-oxobenzo[b]thiophene-2-butanoic acid
  • interferon-β,Inhibitor,TMEM173,ERIS,MPYS,immunity,secretion,tumor,Stimulator of Interferon Genes,MSA 2,MC38,STING,MSA2,TNF-α,MITA,MSA-2,inhibit
  • 4- (5,6-Dimethoxybenzo [b] thiophen-2-yl) -4-oxobutyric acid
  • 4-(5,6-dimethoxy-1-benzothiophen-2-yl)-4-oxobut
  • 129425-81-6
  • 294425-81-6
  • ADC