MSA-2
- Product Name
- MSA-2
- CAS No.
- 129425-81-6
- Chemical Name
- MSA-2
- Synonyms
- MSA-2;5,6-Dimethoxy-γ-oxobenzo[b]thiophene-2-butanoic acid;Benzo[b]thiophene-2-butanoic acid, 5,6-dimethoxy-γ-oxo-;4-(5,6-Dimethoxybenzo[b]thiophen-2-yl)-4-oxobutanoic acid;4- (5,6-Dimethoxybenzo [b] thiophen-2-yl) -4-oxobutyric acid;interferon-β,Inhibitor,TMEM173,ERIS,MPYS,immunity,secretion,tumor,Stimulator of Interferon Genes,MSA 2,MC38,STING,MSA2,TNF-α,MITA,MSA-2,inhibit
- CBNumber
- CB57244028
- Molecular Formula
- C14H14O5S
- Formula Weight
- 294.32
- MOL File
- 129425-81-6.mol
MSA-2 Property
- Boiling point:
- 509.3±50.0 °C(Predicted)
- Density
- 1.336±0.06 g/cm3(Predicted)
- storage temp.
- 4°C, protect from light
- solubility
- DMSO: 125 mg/mL (424.71 mM)
- form
- A crystalline solid
- pka
- 4.35±0.17(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 7353
- Product name
- MSA2
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $569
- Updated
- 2021/12/16
- Product number
- CS-0135308
- Product name
- MSA-2
- Purity
- 98.79%
- Packaging
- 10mg
- Price
- $580
- Updated
- 2021/12/16
- Product number
- AG-CR1-0164-M005
- Product name
- MSA-2
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- CS-0135308
- Product name
- MSA-2
- Purity
- 98.79%
- Packaging
- 5mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- CS-0135308
- Product name
- MSA-2
- Purity
- 98.79%
- Packaging
- 25mg
- Price
- $1100
- Updated
- 2021/12/16
MSA-2 Chemical Properties,Usage,Production
Description
MSA-2 was identified in a phenotypic screen for a chemical inducer of interferon beta secretion. In cell-free assays, MSA-2 binds to human and mouse STING. In tumor-bearing mice, MSA-2 induced elevated interferon-beta in plasma and tumors through two routes of administration.
Uses
MSA-2 is an oral non-nucleotide STING agonist with EC50 of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively.
storage
Store at -20°C