9ALPHA,15S-DIHYDROXY-11-OXO-PROST-13E-EN-1-OIC ACID Property

Melting point:

64.5-65.5 °C

Boiling point:

544.6±50.0 °C(Predicted)

Density 

1.131±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMF: >100 mg/ml (from PGD2); DMSO: >50 mg/ml (from PGD2); Ethanol: >75 mg/ml (from PGD2); PBS pH 7.2: >5 mg/ml (from PGD2)

pka

4.78±0.10(Predicted)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

9ALPHA,15S-DIHYDROXY-11-OXO-PROST-13E-EN-1-OIC ACID Chemical Properties,Usage,Production

Description

Prostaglandin D₁ (PGD₁) is the 1-series analog of PGD₂ . It is an inhibitor of ADP-induced platelet aggregation in humans with an IC₅₀ value of 320 ng/ml, about 1/10 as potent as PGD₂.

Uses

Prostaglandin D1 is used in pharmalogical and in functional characterization of novel EP & DP receptor agonist: DPI receptor mediates penile erection in multiple species.

Definition

ChEBI: Prostaglandin D1 is a prostaglandins D. It has a role as a human metabolite. It is a conjugate acid of a prostaglandin D1(1-).