3,4-DICHLOROPHENACYL BROMIDE

Product Name: 3,4-DICHLOROPHENACYL BROMIDE
CAS No.: 2632-10-2
Chemical Name: 3,4-DICHLOROPHENACYL BROMIDE
Synonyms: 2-BROMO-1-(3,4-DICHLOROPHENYL)ETHAN-1-ONE;AKOS BBS-00003984;2-Bromo-3',4'-dichL;3,4-DICHLOROPHECYL BROMIDE;3,4-DICHLOROPHENACYL BROMIDE;α-Bromo-3,4-dichloroacetophenone;2-Bromo-3',4'-dichloroacetophenone;2-Bromo-3',4'-dichloroacetophenone;ALPHA-BROMO-3,4-DICHLOROACETOPHENONE;2-Bromo-3',4'-dichloroacetophenone 97%
CBNumber: CB5744543
Molecular Formula: C8H5BrCl2O
Formula Weight: 267.93
MOL File: 2632-10-2.mol

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3,4-DICHLOROPHENACYL BROMIDE Property

Melting point:: 54 °C
Boiling point:: 339℃
Density: 1.695
Flash point:: 159℃
storage temp.: 2-8°C
form: powder to crystal
color: White to Light yellow
BRN: 511981
InChI: InChI=1S/C8H5BrCl2O/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3H,4H2
InChIKey: PAKFHEFMTRCFAU-UHFFFAOYSA-N
SMILES: C(=O)(C1=CC=C(Cl)C(Cl)=C1)CBr
CAS DataBase Reference: 2632-10-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,T
Risk Statements: 20/21/22-34-36/37-36/37/38-36-25
Safety Statements: 26-27-36/37/39-36-45
RIDADR: 1759
WGK Germany: 3
HazardClass: 8
PackingGroup: III
HS Code: 29147000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 663174
Product name: 2-Bromo-3′,4′-dichloroacetophenone
Purity: 97%
Packaging: 5g
Price: $69.6
Updated: 2025/07/31

Sigma-Aldrich

Product number: 663174
Product name: 2-Bromo-3′,4′-dichloroacetophenone
Purity: 97%
Packaging: 25g
Price: $216
Updated: 2025/07/31

TCI Chemical

Product number: B2837
Product name: 3,4-Dichlorophenacyl Bromide
Purity: >98.0%(GC)
Packaging: 5g
Price: $64
Updated: 2025/07/31

TCI Chemical

Product number: B2837
Product name: 3,4-Dichlorophenacyl Bromide
Purity: >98.0%(GC)
Packaging: 25g
Price: $261
Updated: 2025/07/31

TRC

Product number: B683355
Product name: 2-Bromo-3'',4''-dichloroacetophenone
Packaging: 1g
Price: $50
Updated: 2021/12/16

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3,4-DICHLOROPHENACYL BROMIDE Chemical Properties,Usage,Production

Uses

2-Bromo-3',4'-dichloroacetophenone is a chemical ragent used in the synthesis of 2-aroylbenzoxazoles. As well, it is used in the synthesis of aminoarylthiazole derivatives as correctors of chloride transport defect in cystic fibrosis patients.

Synthesis

2642-63-9

2632-10-2

General procedure for the synthesis of alpha-bromo-3,4-dichloroacetophenone from 3,4-dichloroacetophenone: to a solution of 3,4-dichloroacetophenone (18.8 g, 0.1 mol, 1.0 eq.) in acetonitrile (100 ml) was added p-toluenesulfonic acid (25.8 g, 0.15 mol, 1.5 eq.) and N-bromosuccinimide (17.7 g, 0.1 mol. 1.0 equiv). The reaction mixture was refluxed at 80 °C for 5 hours. After completion of the reaction, the organic phase was extracted and concentrated, and purified by silica gel column chromatography to afford α-bromo-3,4-dichloroacetophenone (95% yield).

References

[1] Russian Journal of Organic Chemistry, 1994, vol. 30, # 6.1, p. 881 - 887
[2] Zhurnal Organicheskoi Khimii, 1994, vol. 30, # 6, p. 827 - 832
[3] Patent: CN107266388, 2017, A. Location in patent: Paragraph 0098; 0099; 0100
[4] ChemMedChem, 2018, vol. 13, # 11, p. 1102 - 1114
[5] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 21, p. 7146 - 7153

3,4-DICHLOROPHENACYL BROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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3,4-DICHLOROPHENACYL BROMIDE Suppliers

Americas 1 Belgium 1 China 99 Europe 3 France 1 Germany 4 India 8 Japan 2 Slovakia 1 Switzerland 1 Ukraine 1 United Kingdom 10 United States 22 Global 154

Alchemist-pharm chemical Technology Co. Ltd.

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Thermo Fisher Scientific

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View Lastest Price from 3,4-DICHLOROPHENACYL BROMIDE manufacturers

Career Henan Chemical Co

Product: 3,4-DICHLOROPHENACYL BROMIDE 2632-10-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 1ton
Release date: 2019-12-31

2632-10-2, 3,4-DICHLOROPHENACYL BROMIDERelated Search:

3',4'-DICHLOROACETOPHENONE 4-(2,2-DICHLORO-1-METHYL-CYCLOPROPYL)-PHENYLAMINE 3,4-DICHLOROPHENACYL BROMIDE 2,2-DICHLORO-1-PHENYL-CYCLOPROPANECARBALDEHYDE METHYL 3,3-DICHLORO-2-[(2,2-DICHLORO-1-PHENYLCYCLOPROPYL)METHYL]ACRYLATE CYCLOPROTHRIN

2-Bromo-3′,4′-dichloroacetophenone,3,4-Dichlorophenacyl bromide

1-(3,4-Dichlorophenyl)-2-bromoethan-1-one

2-Bromo-1-(3,4-dichlorophenyl)ethan-1-one, 2-Bromo-3',4'-dichloroacetophenone

2-Bromo-3',4'-dichloroacetophenone 97%

3,4-DICHLOROPHECYL BROMIDE

2-BROMO-1-(3,4-DICHLOROPHENYL)ETHAN-1-ONE

2-BROMO-1-(3,4-DICHLOROPHENYL)ETHANONE

AKOS BBS-00003984

ALPHA-BROMO-3,4-DICHLOROACETOPHENONE

3,4-DICHLOROPHENACYL BROMIDE

α-Bromo-3,4-dichloroacetophenone

2-Bromo-3',4'-dichL

Ethanone, 2-bromo-1-(3,4-dichlorophenyl)-

2-Bromo-3',4'-dichloroacetophenone

2-Bromo-3′,4′-dichloroacetophenone, CAS 2632-10-2

2-Bromo-3',4'-dichloroacetophenone

2632-10-2

2362-10-2

2632-10-02

C8H5BrCl2O

C8H5BrCI2O

C7 to C8

Carbonyl Compounds

Building Blocks

Organic Building Blocks

Ketones