ChemicalBook > CAS DataBase List > 3,4-DICHLOROPHENACYL BROMIDE

3,4-DICHLOROPHENACYL BROMIDE

Product Name
3,4-DICHLOROPHENACYL BROMIDE
CAS No.
2632-10-2
Chemical Name
3,4-DICHLOROPHENACYL BROMIDE
Synonyms
2-BROMO-1-(3,4-DICHLOROPHENYL)ETHAN-1-ONE;AKOS BBS-00003984;2-Bromo-3',4'-dichL;3,4-DICHLOROPHECYL BROMIDE;3,4-DICHLOROPHENACYL BROMIDE;α-Bromo-3,4-dichloroacetophenone;2-Bromo-3',4'-dichloroacetophenone;2-Bromo-3',4'-dichloroacetophenone;ALPHA-BROMO-3,4-DICHLOROACETOPHENONE;2-Bromo-3',4'-dichloroacetophenone 97%
CBNumber
CB5744543
Molecular Formula
C8H5BrCl2O
Formula Weight
267.93
MOL File
2632-10-2.mol
More
Less

3,4-DICHLOROPHENACYL BROMIDE Property

Melting point:
54 °C
Boiling point:
339℃
Density 
1.695
Flash point:
159℃
storage temp. 
2-8°C
form 
powder to crystal
color 
White to Light yellow
BRN 
511981
InChI
InChI=1S/C8H5BrCl2O/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3H,4H2
InChIKey
PAKFHEFMTRCFAU-UHFFFAOYSA-N
SMILES
C(=O)(C1=CC=C(Cl)C(Cl)=C1)CBr
CAS DataBase Reference
2632-10-2(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi,T
Risk Statements 
20/21/22-34-36/37-36/37/38-36-25
Safety Statements 
26-27-36/37/39-36-45
RIDADR 
1759
WGK Germany 
3
HazardClass 
8
PackingGroup 
III
HS Code 
29147000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
663174
Product name
2-Bromo-3′,4′-dichloroacetophenone
Purity
97%
Packaging
5g
Price
$69.6
Updated
2025/07/31
Sigma-Aldrich
Product number
663174
Product name
2-Bromo-3′,4′-dichloroacetophenone
Purity
97%
Packaging
25g
Price
$216
Updated
2025/07/31
TCI Chemical
Product number
B2837
Product name
3,4-Dichlorophenacyl Bromide
Purity
>98.0%(GC)
Packaging
5g
Price
$64
Updated
2025/07/31
TCI Chemical
Product number
B2837
Product name
3,4-Dichlorophenacyl Bromide
Purity
>98.0%(GC)
Packaging
25g
Price
$261
Updated
2025/07/31
TRC
Product number
B683355
Product name
2-Bromo-3'',4''-dichloroacetophenone
Packaging
25g
Price
$350
Updated
2021/12/16
More
Less

3,4-DICHLOROPHENACYL BROMIDE Chemical Properties,Usage,Production

Uses

2-Bromo-3',4'-dichloroacetophenone is a chemical ragent used in the synthesis of 2-aroylbenzoxazoles. As well, it is used in the synthesis of aminoarylthiazole derivatives as correctors of chloride transport defect in cystic fibrosis patients.

Synthesis

2642-63-9

2632-10-2

General procedure for the synthesis of alpha-bromo-3,4-dichloroacetophenone from 3,4-dichloroacetophenone: to a solution of 3,4-dichloroacetophenone (18.8 g, 0.1 mol, 1.0 eq.) in acetonitrile (100 ml) was added p-toluenesulfonic acid (25.8 g, 0.15 mol, 1.5 eq.) and N-bromosuccinimide (17.7 g, 0.1 mol. 1.0 equiv). The reaction mixture was refluxed at 80 °C for 5 hours. After completion of the reaction, the organic phase was extracted and concentrated, and purified by silica gel column chromatography to afford α-bromo-3,4-dichloroacetophenone (95% yield).

References

[1] Russian Journal of Organic Chemistry, 1994, vol. 30, # 6.1, p. 881 - 887
[2] Zhurnal Organicheskoi Khimii, 1994, vol. 30, # 6, p. 827 - 832
[3] Patent: CN107266388, 2017, A. Location in patent: Paragraph 0098; 0099; 0100
[4] ChemMedChem, 2018, vol. 13, # 11, p. 1102 - 1114
[5] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 21, p. 7146 - 7153

3,4-DICHLOROPHENACYL BROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3,4-DICHLOROPHENACYL BROMIDE Suppliers

Americas 1 Belgium 1 China 99 Europe 3 France 1 Germany 4 India 8 Japan 2 Slovakia 1 Switzerland 1 Ukraine 1 United Kingdom 10 United States 22 Global 154
Alchemist-pharm chemical Technology Co. Ltd.
Tel
0371-67991738 13783628208
Fax
QQ 412703949
Email
carl@alchemist-pharm.com
Country
China
ProdList
43
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
18515581800 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9400
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Nanjing Norris-Pharm Technology Co., Ltd
Tel
18652989687
Fax
+86-25-52131256
Email
sales@norris-pharm.com
Country
China
ProdList
8878
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Nanjing ShengSai Chemical Co., Ltd.
Tel
025-85205967 13951876367
Fax
025-85205967
Email
shengsaichem@163.com
Country
China
ProdList
818
Advantage
58
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9979
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
14912
Advantage
59
Nanjing Duolong Bio-tech Co.,Ltd.
Tel
18905173768
Fax
025-83263139
Email
52513593@qq.com
Country
China
ProdList
2331
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Changzhou Anxuan Chemical, Co., Ltd.
Tel
13912302692 13912302692;
Fax
0519-88064678
Email
sales@anxuanchem.com
Country
China
ProdList
4828
Advantage
58
NovoChemy Ltd.
Tel
86-(0)21-31261262 373522135
Fax
86-(0)21-33250524
Email
sales@novochemy.com
Country
China
ProdList
6498
Advantage
58
Shanghai Send Pharmaceutical Technology Co., Ltd.
Tel
021-58088081 Q2635253576
Fax
QQ3382968513
Email
hailey@shsendpharm.com
Country
China
ProdList
2081
Advantage
55
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7991
Advantage
55
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
6687
Advantage
55
Shanghai Qiao Chemical Science Co., Ltd
Tel
021-58892003
Email
info@qiaochem.com
Country
China
ProdList
6059
Advantage
65
Shanghai Xilong Biochemical Technology Co., Ltd.
Tel
021-52907766-8042
Fax
021-52906523
Country
China
ProdList
9941
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Chengdu Huachun Technology Co., Ltd
Tel
400-1166-196 15982826727
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Grader reagent
Tel
18221735425
Email
sales@xinpingchem.com
Country
China
ProdList
9942
Advantage
58
Shanghai CR Corporation Limited
Tel
13062833949; 4006653949 4006653949
Fax
QQ: 2136646215
Email
fred.wen@crcorporation.cn
Country
China
ProdList
9757
Advantage
58
Shanghai BaiShun Biological Technology Co., Ltd
Tel
021-37581181
Fax
021-57456066
Email
sales@chem-mall.com
Country
China
ProdList
10330
Advantage
58
Shanghai Zhen Li Biological Technology Co., Ltd
Tel
021-16621358918; 18516310516
Fax
13045646768
Email
zhenlipharma888@163.com
Country
China
ProdList
19035
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6039 18920764717
Email
sales@heowns.com
Country
China
ProdList
23771
Advantage
60
Alchemist-pharm chemical Technology Co. Ltd.
Tel
0371-67991738 13783628208
Fax
QQ 412703949
Email
carl@alchemist-pharm.com
Country
China
ProdList
1872
Advantage
58
3A Chemicals
Tel
400-668-9898
Fax
010-51582189
Email
service@3achem.com
Country
China
ProdList
20557
Advantage
58
Shanghai SPAR pharmaceutical technology co., LTD
Tel
021-000000 13917643586;
Email
admin@jingshipharmatech.com
Country
China
ProdList
9856
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Cool Pharm, Ltd
Tel
021-58581007 18019463053
Fax
021-50966098
Email
sales@coolpharm.com
Country
China
ProdList
12878
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418671 +8618949823763
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34563
Advantage
58
sgtlifesciences pvt ltd
Tel
+8617013299288
Email
dj@sgtlifesciences.com
Country
China
ProdList
12373
Advantage
58
Hubei Ipure Biology Co., Ltd
Tel
+8613367258412
Fax
18062427325
Email
ada@ipurechemical.com
Country
China
ProdList
10237
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Win-Win chemical CO., Limited
Tel
+86-0086-577-64498589 +86-15355981851
Fax
0086-577-56994596
Email
sales@win-winchemical.com
Country
China
ProdList
14359
Advantage
58
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Email
chemwill_asia@126.com
Country
CHINA
ProdList
23912
Advantage
58
Wuhan Chemwish Technology Co., Ltd
Tel
027-67849912
Email
sales@chemwish.com
Country
CHINA
ProdList
10821
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29798
Advantage
58
More
Less

View Lastest Price from 3,4-DICHLOROPHENACYL BROMIDE manufacturers

Career Henan Chemical Co
Product
3,4-DICHLOROPHENACYL BROMIDE 2632-10-2
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
1ton
Release date
2019-12-31

2632-10-2, 3,4-DICHLOROPHENACYL BROMIDERelated Search:

3',4'-DICHLOROACETOPHENONE 4-(2,2-DICHLORO-1-METHYL-CYCLOPROPYL)-PHENYLAMINE 3,4-DICHLOROPHENACYL BROMIDE 2,2-DICHLORO-1-PHENYL-CYCLOPROPANECARBALDEHYDE METHYL 3,3-DICHLORO-2-[(2,2-DICHLORO-1-PHENYLCYCLOPROPYL)METHYL]ACRYLATE CYCLOPROTHRIN

  • 2-Bromo-3′,4′-dichloroacetophenone,3,4-Dichlorophenacyl bromide
  • 1-(3,4-Dichlorophenyl)-2-bromoethan-1-one
  • 2-Bromo-1-(3,4-dichlorophenyl)ethan-1-one, 2-Bromo-3',4'-dichloroacetophenone
  • 2-Bromo-3',4'-dichloroacetophenone 97%
  • 3,4-DICHLOROPHECYL BROMIDE
  • 2-BROMO-1-(3,4-DICHLOROPHENYL)ETHAN-1-ONE
  • 2-BROMO-1-(3,4-DICHLOROPHENYL)ETHANONE
  • AKOS BBS-00003984
  • ALPHA-BROMO-3,4-DICHLOROACETOPHENONE
  • 3,4-DICHLOROPHENACYL BROMIDE
  • α-Bromo-3,4-dichloroacetophenone
  • 2-Bromo-3',4'-dichL
  • Ethanone, 2-bromo-1-(3,4-dichlorophenyl)-
  • 2-Bromo-3',4'-dichloroacetophenone
  • 2-Bromo-3′,4′-dichloroacetophenone, CAS 2632-10-2
  • 2-Bromo-3',4'-dichloroacetophenone
  • 2632-10-2
  • 2362-10-2
  • 2632-10-02
  • C8H5BrCl2O
  • C8H5BrCI2O
  • C7 to C8
  • Carbonyl Compounds
  • Building Blocks
  • Organic Building Blocks
  • Ketones