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PTIO

Product Name
PTIO
CAS No.
18390-00-6
Chemical Name
PTIO
Synonyms
PTIO;PTIO,98%;PTIO PTIO - CAS 18390-00-6;PTIO - CAS 18390-00-6 - Calbiochem;2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-3-OXIDE-1-OXYL;2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-1-OXYL-3-OXIDE;PTIO (2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-3-OXIDE-1-OXYL);4,5-DIHYDRO-4,4,5,5-TETRAMETHYL-2-PHENYL-1H-IMIDAZOL-1-YLOXY-1-OXIDE;[[4,4,5,5-Tetramethyl-2-phenyl-2-imidazoline 3-oxide]-1-yloxy]radical
CBNumber
CB5747094
Molecular Formula
C13H17N2O2*
Formula Weight
233.29
MOL File
18390-00-6.mol
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PTIO Property

Melting point:
approximate 86℃
storage temp. 
2-8°C
solubility 
soluble in Methanol
form 
Dark blue solid
color 
Blue to Dark blue
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
2933.99.8210
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P5084
Product name
PTIO
Packaging
25mg
Price
$119.4
Updated
2024/03/01
Sigma-Aldrich
Product number
523350
Product name
PTIO
Purity
Nitric oxide radical scavenger.
Packaging
25mg
Price
$182
Updated
2024/03/01
TCI Chemical
Product number
A5440
Product name
PTIO (=2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl) [Stable free radical reagent for the simultaneous determination of NO and NO2 in the atmosphere]
Purity
>98.0%(T)
Packaging
1g
Price
$150
Updated
2024/03/01
TCI Chemical
Product number
A5440
Product name
PTIO (=2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl) [Stable free radical reagent for the simultaneous determination of NO and NO2 in the atmosphere]
Purity
>98.0%(T)
Packaging
5g
Price
$450
Updated
2024/03/01
Cayman Chemical
Product number
14982
Product name
PTIO
Purity
≥98%
Packaging
25mg
Price
$37
Updated
2024/03/01
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PTIO Chemical Properties,Usage,Production

Description

PTIO is an oxidizing reagent that reacts with nitric oxide to form nitric dioxide and corresponding imino nitroxides. It can be used to assay nitric oxide production when examining nitric oxide synthase inhibitory activity.

Chemical Properties

blue crystals

Uses

PTIO is a nitric oxide (NO) radical scavenger used to inhibit physiological effects of NO.

Uses

2-phenyl-4, 4, 5, 5,-tetramethylimidazoline-1-oxyl 3-oxide (PTIO) has been used as a nitric oxide (NO) scavenger.

Synthesis Reference(s)

Journal of the American Chemical Society, 90, p. 1078, 1968 DOI: 10.1021/ja01006a053

General Description

Nitric oxide radical scavenger. Reacts with nitric oxide in a stoichiometric manner without affecting nitric oxide synthase activity. Inhibits the enhanced vascular permeability in solid tumors.

Biochem/physiol Actions

Product does not compete with ATP.

PTIO Preparation Products And Raw materials

Raw materials

Preparation Products

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PTIO Suppliers

Americas 1 China 69 Europe 1 Germany 2 India 2 Japan 4 Switzerland 2 United Kingdom 1 United States 10 Global 92
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75

18390-00-6, PTIORelated Search:

Oxazoline 2-Phenyl-2-imidazoline PTIO 2-(4-CARBOXYPHENYL)-4,4,5,5-TETRAMETHYLIMIDAZOLINE-1-OXYL-3-OXIDE, NA 2-(4-NITROPHENYL)-4,4,5,5-TETRAMETHYLIMIDAZOLINE-3-OXIDE-1-OXYL 3,3,4,4-TETRAMETHYL-2-TRIMETHYLAMMONIOPHENYL-2-IMIDAZOLINE-3-OXIDE-1-YLOXY CHLORIDE 2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide CARBOXY-PTIO 1H-IMIDAZOL-1-YLOXY, 2-(1,3-BENZODIOXOL-5-YL)-4,5-DIHYDRO-4,4,5,5-TETRAMETHYL-, 3-OXIDE

  • 2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl)[stablefreeradicalreagentforthesimultaneousdetermin
  • 2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-1-OXYL-3-OXIDE
  • 2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-3-OXIDE-1-OXYL
  • PTIO
  • PTIO (2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-3-OXIDE-1-OXYL)
  • PTIO (=2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl) [Stable free radical reagent for the simultaneous determination of NO and NO2 in the atmosphere]
  • [(2-Phenyl-4,4,5,5-tetramethyl-3-oxylato-4,5-dihydro-1H-imidazole-3-ium)-1-yloxy]radical
  • [(4,5-Dihydro-2-phenyl-4,4,5,5-tetramethyl-1H-imidazole-3-oxide)-1-yloxy]radical
  • [[(2-Phenyl-3-oxylato-4,4,5,5-tetramethyl-1H-imidazole-3-ium)-1-yl]oxy]radical
  • [[2-Phenyl-4,4,5,5-tetramethyl-2-imidazoline 3-oxide]-1-yloxy]radical
  • [[4,4,5,5-Tetramethyl-2-phenyl-2-imidazoline 3-oxide]-1-yloxy]radical
  • PTIO,98%
  • 4,5-Dihydro-4,4,5,5-tetramethyl-2-phenyl-1H-imidazol-1-yloxy-1-oxide 2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl
  • (=2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl) [Stable free radical reagent for the simultaneous determination of NO and NO2 in the atmosphere]
  • PTIO&nbsp
  • PTIO (=2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl) [Stable free radical reagent for the simultaneous determination of NO and NO<sub>2</sub> in the atmosphere]
  • 4,5-DIHYDRO-4,4,5,5-TETRAMETHYL-2-PHENYL-1H-IMIDAZOL-1-YLOXY-1-OXIDE
  • PTIO - CAS 18390-00-6 - Calbiochem
  • PTIO（4,5-Dihydro-4,4,5,5-tetramethyl-2-phenyl-1H-imidazol-1-yloxy-1-oxide）
  • PTIO (=2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl)[Stable free radical reagent for the simultaneous determination of NO and NO2 in the atmosphere]&gt
  • PTIO - CAS 18390-00-6
  • 18390-00-6
  • C13H17N2O2
  • Nitric Oxide Metabolism
  • Enzymes, Inhibitors, and Substrates
  • Nitric Oxide Scavengers
  • BioChemical
  • Biochemicals and Reagents
  • Application Index
  • Cell Signaling Enzymes