ChemicalBook > CAS DataBase List > 1,2,3-BENZOTRIAZIN-4(3H)-ONE

1,2,3-BENZOTRIAZIN-4(3H)-ONE

Product Name
1,2,3-BENZOTRIAZIN-4(3H)-ONE
CAS No.
90-16-4
Chemical Name
1,2,3-BENZOTRIAZIN-4(3H)-ONE
Synonyms
benzo[d][1,2,3]triazin-4(3H)-one;usafma-2;NSC 13563;NSC 20121;USAF Ma-2;BENZAZIMIDE;Benzazimidone;BenzotriazinHone;Benzoketotriazine;4-KETOBENZTRIAZINE
CBNumber
CB5747711
Molecular Formula
C7H5N3O
Formula Weight
147.13
MOL File
90-16-4.mol
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1,2,3-BENZOTRIAZIN-4(3H)-ONE Property

Melting point:
216-218 °C (lit.)
Boiling point:
282℃
Density 
1.47
refractive index 
1.5500 (estimate)
Flash point:
125℃
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Soluble in most organic solvents.
pka
-4.67±0.20(Predicted)
form 
Solid
color 
Needles from cyclohexane
BRN 
124996
InChI
InChI=1S/C7H5N3O/c11-7-5-3-1-2-4-6(5)8-10-9-7/h1-4H,(H,8,9,11)
InChIKey
DMSSTTLDFWKBSX-UHFFFAOYSA-N
SMILES
N1C2=CC=CC=C2C(=O)NN=1
CAS DataBase Reference
90-16-4(CAS DataBase Reference)
EPA Substance Registry System
1,2,3-Benzotriazin-4(1H)-one (90-16-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
RTECS 
DM0800000
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
2933698090
Hazardous Substances Data
90-16-4(Hazardous Substances Data)
Toxicity
LD50 ipr-mus: 50 mg/kg NTIS** AD277-689
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
340545
Product name
1,2,3-Benzotriazin-4(3H)-one
Purity
98%
Packaging
5g
Price
$95.5
Updated
2023/06/20
TCI Chemical
Product number
K0003
Product name
3,4-Dihydro-4-oxo-1,2,3-benzotriazine
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$30
Updated
2025/07/31
TCI Chemical
Product number
K0003
Product name
3,4-Dihydro-4-oxo-1,2,3-benzotriazine
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$82
Updated
2025/07/31
TRC
Product number
B206930
Product name
1,2,3-Benzotriazin-4(3H)-one
Packaging
100g
Price
$745
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0017124
Product name
1,2,3-BENZOTRIAZIN-4(3H)-ONE
Purity
95.00%
Packaging
5G
Price
$808.96
Updated
2021/12/16
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1,2,3-BENZOTRIAZIN-4(3H)-ONE Chemical Properties,Usage,Production

Chemical Properties

Tan powder. Soluble in alkaline solutions and organic bases.

Uses

Organic synthesis.

Uses

1,2,3-Benzotriazin-4(3H)one is used to prepare 3-methoxymethyl-3H-benzo[d][1,2,3]triazin-4-one by reacting with dimethoxymethane. Further, it undergoes thermal condensation with alfa-amino acids to give 3H-1,4-benzodiazepin-(1H,4H)-2,5-diones. In addition to this, it is employed as a reagent to synthesize 1,2,3-bBenzotriazin-4-one-arylpiperazine derivatives.

Uses

1,2,3-Benzotriazin-4(3H)-one is part of a group of compounds that exhibit antimicrobial activity. 1,2,3-Benzotriazin-4(3H)-one is also used as a reagent to synthesize 1,2,3-Benzotriazin-4-one-arylpiperazine derivatives, compounds that act as Serotonin (HCl: S274980) receptor ligands.

Definition

Bicyclic.

General Description

1,2,3-Benzotriazin-4(3H)-one is an 1,2,3-benzotriazine derivative. 1,2,3-Benzotriazin-4(3H)-one undergoes thermal condensation with α-amino acids to yield 3H-1,4-benzodiazepin-(1H,4H)-2,5-diones. 1,2,3-benzotriazin-4(3H)-one on thermolysis yields quinazolino[3,2-c][1,2,3]benzotriazin-8-one.

Safety Profile

Poison by intraperitoneal route.Experimental reproductive effects. When heated todecomposition it emits toxic fumes of NOx.

1,2,3-BENZOTRIAZIN-4(3H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,2,3-BENZOTRIAZIN-4(3H)-ONE Suppliers

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View Lastest Price from 1,2,3-BENZOTRIAZIN-4(3H)-ONE manufacturers

Career Henan Chemical Co
Product
1,2,3-BENZOTRIAZIN-4(3H)-ONE 90-16-4
Price
US $9.80/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg -1000kg
Release date
2020-01-02

90-16-4, 1,2,3-BENZOTRIAZIN-4(3H)-ONERelated Search:

Fmoc-O-tert-Butyl-L-serine 3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl ester DEPBT 3-Hydroxy-1,2,3-benzotriazin-4(3H)-one AZINPHOS-ETHYL AZINPHOS-METHYL 1,2,3-BENZOTRIAZIN-4(3H)-ONE N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)uronium tetrafluoroborate Razinodil FMOC-THR(TBU)-ODHBT 3-(hydroxymethyl)-4-ketobenz-1,2,3-triazine Fmoc-Glu(OBut)-ODhbt Fmoc-Gly-ODhbt AZINPHOS-METHYL OXON Fmoc-Asp(OBut)-ODhbt 1,2,3-BENZOTRIAZIN-4(3H)-ONE, 6-BROMO- Molinazone 3-(4-BROMOBENZYL)-1,2,3-BENZOTRIAZIN-4(3H)-ONE 3-(1-Phenyl-1H-pyrazol-5-yl)-1,2,3-benzotriazin-4(3H)-one

  • 1,2,3-Benzotriazin-4(3H)-one 98%
  • 1,2,3-benzotriazin-4-(1h)-one
  • 1,2,3-benzotriazin-4(1h)-one
  • 1,2,3-Benzotriazin-4-ol
  • 1,2,3-benzotriazin-4-one
  • 3H-1,2,3-Benzotriazin-4-one
  • 4-keto-(3h)-1,2,3-benzotriazine
  • 4-Ketobenz-1,2,3-triazine
  • 1,2,3-Benzotriazine-4(3H)-one 4-Ketobenzotriazine
  • benzo[d][1,2,3]triazin-4(3H)-one
  • 1H-1,2,3-benzotriazin-4-one
  • BENZAZIMIDE
  • BENZO-1,2,3-TRIAZIN-4(3H)-ONE
  • 4-Ketobenzo-1,2,3(3H)-triazine
  • BenzotriazinHone
  • 3,4-Dihydro-1,2,3-benzotriazin-4-one
  • 3,4-DIHYDRO-4-OXO-1,2,3-BENZOTRIAZINE 98+%
  • 1,2,3-BENZOTRIAZINE-4(3H)-ONE
  • 1,2,3-BENZOTRIAZIN-4(3H)-ONE
  • 1,2,3-Triazanaphthalene-4(3H)-one
  • NSC 13563
  • NSC 20121
  • 4-Ketobenzotriazene
  • Benzazimidone
  • Benzoketotriazine
  • ceto-4benzotriazine-1,2,3
  • USAF Ma-2
  • usafma-2
  • 4-KETO-3H-1,2,3-BENZOTRIAZENE
  • 4-KETO(3H)-3,4-DIHYDRO-1,2,3-BENZTRIAZINE
  • 4-KETOBENZOTRIAZINE
  • 4-KETOBENZTRIAZINE
  • 3,4-DIHYDRO-4-OXO-1,2,3-BENZOTRIAZINE
  • 3,4-Dihydro-4-oxo-1,2,3-benzotriazine&gt
  • 1,2,3-Benzotriazin-4(3<i>H</i>)-one
  • 90-16-4
  • Building Blocks
  • Heterocyclic Building Blocks
  • Triazines
  • pharmacetical
  • Heterocyclic Compounds
  • Building Blocks
  • Heterocyclic Building Blocks
  • Triazines