ChemicalBook > CAS DataBase List > ANTI-HAP1
ANTI-HAP1
- Product Name
- ANTI-HAP1
- Chemical Name
- ANTI-HAP1
- Synonyms
- ANTI-APE;Anti-GIV;Anti-APX;ANTI-APEX;ANTI-APE1;ANTI-AP L;ANTI-APEN;ANTI-HAP1;Anti-GRDN;ANTI-REF-1
- CBNumber
- CB5752436
- Formula Weight
- 0
- MOL File
- Mol file
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ANTI-HAP1 Property
- storage temp.
- −20°C
- form
- buffered aqueous solution
- biological source
- rabbit
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- HPA038102
- Product name
- Anti-CCDC88A antibody produced in rabbit
- Purity
- Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
- Packaging
- 100μL
- Price
- $580
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- HPA002564
- Product name
- Anti-APEX1 antibody produced in rabbit
- Purity
- Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
- Packaging
- 100μL
- Price
- $514
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- HPA038102
- Product name
- Anti-CCDC88A antibody produced in rabbit
- Purity
- Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
- Packaging
- 25μL
- Price
- $282
- Updated
- 2023/06/20
Sigma-Aldrich
- Product number
- HPA002564
- Product name
- Anti-APEX1 antibody produced in rabbit
- Purity
- Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
- Packaging
- 25μL
- Price
- $282
- Updated
- 2023/06/20
Sigma-Aldrich
- Product number
- SAB3500436
- Product name
- Anti-HAP1 antibody produced in rabbit
- Purity
- affinity isolated antibody, buffered aqueous solution
- Packaging
- 100μG
- Price
- $507
- Updated
- 2023/01/07
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ANTI-HAP1 Chemical Properties,Usage,Production
Biological Activity
The gene HAP1 (huntingtin-associated protein 1) is a bifunctional enzyme th at functions as a DNA repair enzyme as well as in redox activation of transcription factors. It binds to the Huntingtonμs disease (HD) protein huntingtin in a polyglutamine length-dependent manner. It associates with huntingtin via the cytoskeletal proteins dynactin and pericentriolar autoantigen protein 1 forming coiled-coils. It plays a role in vesicle trafficking by facilitating interactions among cytoskeletal, vesicular and motor proteins. It is an apurinic/apyrimidinic (AP) site-specific DNA repair endonuclease th at removes the AP sites produced naturally or by cytotoxic drugs and radiation. It also has RNAse H activity and controls the redox state of certain proto-oncogene products, such as the transcription factor c-Jun. The HAP1 protein is a candidate for pathology associated with HD.
ANTI-HAP1 Preparation Products And Raw materials
Raw materials
Preparation Products
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ANTI-HAP1 Suppliers
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