4-Iodo-1-methyl-1H-imidazole
- Product Name
- 4-Iodo-1-methyl-1H-imidazole
- CAS No.
- 71759-87-0
- Chemical Name
- 4-Iodo-1-methyl-1H-imidazole
- Synonyms
- 4-IODO-1-METHYLIMIDAZOLE;EOS-60756;1-Methyl-4-iodoimidazole;4-Iodine-1-methylimidazole;4(5)-IODO-1-METHYLIMIDAZOLE;4-Iodo-1-Methyl-1H-iMidaz...;4-IODO-1-METHYL-1H-IMIDAZOLE;1H-IMIDAZOLE, 4-IODO-1-METHYL-;4-Iodo-1-methyl-1H-imidazole 98%min
- CBNumber
- CB5754223
- Molecular Formula
- C4H5IN2
- Formula Weight
- 208
- MOL File
- 71759-87-0.mol
4-Iodo-1-methyl-1H-imidazole Property
- Melting point:
- 51-54°C
- Boiling point:
- 299.0±13.0 °C(Predicted)
- Density
- 2.07±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- solubility
- Dichlomethane (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 4.46±0.61(Predicted)
- color
- Pale Beige
- InChI
- InChI=1S/C4H5IN2/c1-7-2-4(5)6-3-7/h2-3H,1H3
- InChIKey
- HUQSHNLGOKQVHA-UHFFFAOYSA-N
- SMILES
- C1N(C)C=C(I)N=1
- CAS DataBase Reference
- 71759-87-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- Hazard Note
- Irritant
- HS Code
- 2933299090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- I708450
- Product name
- 4-Iodo-1-methylimidazole
- Packaging
- 10g
- Price
- $475
- Updated
- 2021/12/16
- Product number
- 96112
- Product name
- 4-Iodo-1-methylimidazole
- Packaging
- 1g
- Price
- $435
- Updated
- 2021/12/16
- Product number
- 3H32-H-X1
- Product name
- 4-Iodo-1-methyl-1H-imidazole
- Packaging
- 10g
- Price
- $261
- Updated
- 2021/12/16
- Product number
- 96112
- Product name
- 4-Iodo-1-methylimidazole
- Packaging
- 250mg
- Price
- $365
- Updated
- 2021/12/16
- Product number
- AK-29464
- Product name
- 4-Iodo-1-methyl-1H-imidazole
- Purity
- 98%
- Packaging
- 25g
- Price
- $371
- Updated
- 2021/12/16
4-Iodo-1-methyl-1H-imidazole Chemical Properties,Usage,Production
Uses
4-Iodo-1-methylimidazole is a chemical reagent used in the synthesis of PET (positron emission tomography) tracers for imaging brain enzymes.
Synthesis
37067-96-2
71759-87-0
General procedure for the synthesis of 4-iodo-1-methyl-1H-imidazole from 4,5-diiodo-1-methyl-1H-imidazole: At room temperature, EtMgBr (3.0 M ether solution, 11.00 mL, 32.9 mmol) was slowly added dropwise to 4,5-diiodo-1-methyl-1H-imidazole (10.00 g, 29.9 mmol) in anhydrous CH2Cl2 ( 150 mL) solution for more than 15 minutes dropwise. The reaction mixture was then stirred for 20 minutes. After confirming complete consumption of the feedstock by TLC monitoring, the reaction was quenched by adding water (20 mL) to the reaction mixture. The organic and aqueous layers were separated and the aqueous layer was extracted with CH2Cl2 (3 x 50 mL). All organic layers were combined, dried with anhydrous Na2SO4 and concentrated under reduced pressure to afford 4-iodo-1-methylimidazole (15) as a light brown oil (5.86 g, 94% yield).
References
[1] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 5, p. 1608 - 1621
[2] Journal of Organometallic Chemistry, 2012, vol. 697, # 1, p. 33 - 40
[3] Heterocycles, 2003, vol. 60, # 1, p. 1 - 7
[4] Polish Journal of Chemistry, 1981, vol. 55, # 7/8, p. 1659 - 1665
[5] Journal of Organic Chemistry, 2007, vol. 72, # 10, p. 3741 - 3749
4-Iodo-1-methyl-1H-imidazole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Iodo-1-methyl-1H-imidazole manufacturers
- Product
- 4-Iodo-1-methyl-1H-imidazole 71759-87-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 2000
- Release date
- 2025-09-10
- Product
- 4-Iodo-1-methyl-1H-imidazole 71759-87-0
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-08-21
- Product
- 4-Iodo-1-methyl-1H-imidazole 71759-87-0
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2018-12-17