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NF449

Product Name
NF449
CAS No.
389142-38-5
Chemical Name
NF449
Synonyms
NF449;NF449 OCTASODIUM SALT;NF449 - CAS 389142-38-5 - Calbiochem;1,3-Benzenedisulfonic acid, 4,4',4'',4'''-[carbonylbis[imino-5,1,3-benzenetriylbis(carbonylimino)]]tetrakis-;4,4',4'',4'''-(Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino)))tetrakis-1,3-benzenedisulfonicacid,octasodium;4,4',4'',4'''-[CARBONYL-BIS[IMINO-5,1,3-BENZENETRIYL BIS-(CARBONYLIMINO)]]TETRAKIS-(BENZENE-1,3-DISULFONIC ACID, 8NA);4,4',4'',4'''-[Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino))]tetrakis-1,3-benzenedisulfonic acid octasodium salt;4,4',4'',4'''-[CARBONYLBIS(IMINO-5,1,3-BENZENETRIYL-BIS(CARBONYLIMINO))]TETRAKIS-1,3-BENZENEDISULFONIC ACID, OCTASODIUM SALT;4,4μ,4,4μ-[Carbonylbis[imino-5,1,3-benzenetriyl bis(carbonyl-imino)]]tetrakis(benzene-1,3-disulfonic acid) octasodium salt;4,4',4'',4'''-[CARBONYL-BIS[IMINO-5,1,3-BENZENETRIYL BIS-(CARBONYL-IMINO)]]TETRAKIS(BENZENE-1,3-DISULFONIC ACID) OCTASODIUM SALT
CBNumber
CB5764453
Molecular Formula
C41H32N6O29S8
Formula Weight
1329.24
MOL File
389142-38-5.mol
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NF449 Property

Melting point:
>300°C
Density 
1.991±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
H2O: soluble
form 
solid
pka
-2.03±0.50(Predicted)
color 
white
Stability:
Hygroscopic
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
480420
Product name
NF449
Packaging
10mg
Price
$227.55
Updated
2021/12/16
Tocris
Product number
1391
Product name
NF449
Packaging
10
Price
$236
Updated
2021/12/16
Tocris
Product number
1391
Product name
NF449
Packaging
50
Price
$992
Updated
2021/12/16
Usbiological
Product number
165610
Product name
NF449
Packaging
10mg
Price
$403
Updated
2021/12/16
Usbiological
Product number
255975
Product name
NF 449
Packaging
10mg
Price
$489
Updated
2021/12/16
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NF449 Chemical Properties,Usage,Production

Uses

NF449 is a known P2X1 receptor antagonist used to regulate the intravascular platelet aggregation commonly seen in systematic thromboembolism.

Biological Activity

Potent purinergic receptor antagonist that displays high selectivity for P2X 1 (IC 50 values are 0.28, 0.69, 120, 1820, 47000 and > 300000 nM for rP2X 1 , rP2X 1+5 , rP2X 2+3 , rP2X 3 , rP2X 2 and P2X 4 receptors respectively). Provides antithrombotic protection in vivo . Also acts as a G s α -selective antagonist.

NF449 Preparation Products And Raw materials

Raw materials

Preparation Products

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NF449 Suppliers

Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77
VWR International
Tel
--
Fax
--
Email
solutions@vwr.com
Country
United Kingdom
ProdList
6548
Advantage
82

389142-38-5, NF449Related Search:


  • 4,4',4'',4'''-[CARBONYLBIS(IMINO-5,1,3-BENZENETRIYL-BIS(CARBONYLIMINO))]TETRAKIS-1,3-BENZENEDISULFONIC ACID, OCTASODIUM SALT
  • 4,4',4'',4'''-[CARBONYL-BIS[IMINO-5,1,3-BENZENETRIYL BIS-(CARBONYL-IMINO)]]TETRAKIS(BENZENE-1,3-DISULFONIC ACID) OCTASODIUM SALT
  • 4,4',4'',4'''-[CARBONYL-BIS[IMINO-5,1,3-BENZENETRIYL BIS-(CARBONYLIMINO)]]TETRAKIS-(BENZENE-1,3-DISULFONIC ACID, 8NA)
  • NF449
  • NF449 OCTASODIUM SALT
  • 4,4',4'',4'''-(Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino)))tetrakis-1,3-benzenedisulfonicacid,octasodium
  • 4,4μ,4,4μ-[Carbonylbis[imino-5,1,3-benzenetriyl bis(carbonyl-imino)]]tetrakis(benzene-1,3-disulfonic acid) octasodium salt
  • NF449 - CAS 389142-38-5 - Calbiochem
  • 4,4',4'',4'''-[Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino))]tetrakis-1,3-benzenedisulfonic acid octasodium salt
  • 1,3-Benzenedisulfonic acid, 4,4',4'',4'''-[carbonylbis[imino-5,1,3-benzenetriylbis(carbonylimino)]]tetrakis-
  • 389142-38-5
  • C41H24N6Na8O29S8
  • Purinergics P2 receptor