ChemicalBook > CAS DataBase List > 4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER
4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER
- Product Name
- 4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER
- CAS No.
- 191102-87-1
- Chemical Name
- 4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER
- Synonyms
- GGTI-2147;GGTI-2147 (GGTI2147);TUQRZGWNDBXSNP-SANMLTNESA-N;Geranylgeranyl transferase inhibitor-2147;4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER;L-Leucine, N-[4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester
- CBNumber
- CB5766770
- Molecular Formula
- C28H30N4O3
- Formula Weight
- 470.56
- MOL File
- Mol file
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4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Property
- Boiling point:
- 710.6±60.0 °C(Predicted)
- Density
- 1.224±0.06 g/cm3(Predicted)
- solubility
- Soluble in DMSO
- pka
- 13.22±0.46(Predicted)
- form
- Solid
- Sensitive
- Light Sensitive & Hygroscopic
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 345885
- Product name
- GGTI-2147 - CAS 191102-87-1 - Calbiochem
- Purity
- A cell-permeable non-thiol peptidomimetic that acts as a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I).
- Packaging
- 250μG
- Price
- $245
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- J65022
- Product name
- GGTI-2147
- Packaging
- 100microg
- Price
- $591
- Updated
- 2021/12/16
TRC
- Product number
- G368900
- Product name
- GGTI-2147
- Packaging
- 5mg
- Price
- $1470
- Updated
- 2021/12/16
TRC
- Product number
- G368900
- Product name
- GGTI-2147
- Packaging
- 0.1mg
- Price
- $115
- Updated
- 2021/12/16
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4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Chemical Properties,Usage,Production
Uses
GGTI-2147 is an inhibitors of protein geranylgeranyltransferase-I and protein prenylation. Increases prelamin A accumulation by inhibiting ZMPSTE24 protein in human fibroblast and increases cytosolic accumulation of Rac1 and elicites significant inhibition of GSIS from INS 832/13 cells.
4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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