4-DIFLUOROMETHOXY-3-METHOXY-BENZALDEHYDE
- Product Name
- 4-DIFLUOROMETHOXY-3-METHOXY-BENZALDEHYDE
- CAS No.
- 162401-70-9
- Chemical Name
- 4-DIFLUOROMETHOXY-3-METHOXY-BENZALDEHYDE
- Synonyms
- AKOS B014002;AKOS BBS-00006582;TIMTEC-BB SBB009330;ART-CHEM-BB B014002;ASINEX-REAG BAS 11524503;4-DIFLUOROMETHOXY-3-METHOXY-BENZALDEHYDE;3-Methoxy-4-(difluoromethoxy)benzaldehyde;Benzaldehyde,4-(difluoroMethoxy)-3-Methoxy-;4-(DIFLUOROMETHOXY)-3-METHOXYBENZALDEHYDE, 98% MIN.
- CBNumber
- CB5767515
- Molecular Formula
- C9H8F2O3
- Formula Weight
- 202.15
- MOL File
- 162401-70-9.mol
4-DIFLUOROMETHOXY-3-METHOXY-BENZALDEHYDE Property
- Boiling point:
- 105-106°C 1mm
- Density
- 1.260±0.06 g/cm3(Predicted)
- refractive index
- 1.5155
- storage temp.
- Inert atmosphere,2-8°C
- form
- liquid
- color
- Clear, light orange
- Sensitive
- Air Sensitive
- InChI
- InChI=1S/C9H8F2O3/c1-13-8-4-6(5-12)2-3-7(8)14-9(10)11/h2-5,9H,1H3
- InChIKey
- KGPOVKAYCXTCQS-UHFFFAOYSA-N
- SMILES
- C(=O)C1=CC=C(OC(F)F)C(OC)=C1
- CAS DataBase Reference
- 162401-70-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- HazardClass
- IRRITANT
- HS Code
- 2913000090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- D445208
- Product name
- 4-(Difluoromethoxy)-3-methoxybenzaldehyde
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- D445208
- Product name
- 4-(Difluoromethoxy)-3-methoxybenzaldehyde
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- J96783
- Product name
- 4-Difluoromethoxy-3-methoxybenzaldehyde
- Packaging
- 1g
- Price
- $22
- Updated
- 2021/12/16
- Product number
- 2615-3-11
- Product name
- 4-(Difluoromethoxy)-3-methoxybenzaldehyde
- Purity
- 98%
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- J96783
- Product name
- 4-Difluoromethoxy-3-methoxybenzaldehyde
- Packaging
- 10g
- Price
- $102
- Updated
- 2021/12/16
4-DIFLUOROMETHOXY-3-METHOXY-BENZALDEHYDE Chemical Properties,Usage,Production
Synthesis
75-45-6
121-33-5
162401-70-9
1. DMF (450 mL), vanillin (30.0 g, 0.2 mol) and sodium hydroxide (13.0 g, 0.325 mol) were added to a reaction flask. 2. The reaction system was warmed to 90 °C with continuous stirring for 2 hours. 3. Monochlorodifluoromethane gas was introduced into the reaction system and the reaction progress was monitored by TLC until the vanillin was completely consumed. 4. Upon completion of the reaction, the heating was stopped and the reaction system was cooled to room temperature. 5. The reaction was quenched by addition of water (450 mL) and the reaction mixture was extracted with dichloromethane. 6. The organic phase was washed sequentially with saturated sodium carbonate solution and saturated brine, then dried over anhydrous sodium sulfate. 7. Concentrate the organic phase under pressure to obtain a light yellow oil 3-methoxy-4-(difluoromethoxy)benzaldehyde (31.9 g, 80% yield, 99.2% purity, HPLC chromatogram in Fig. 1), which can be used in subsequent steps without further purification.
References
[1] Chinese Chemical Letters, 2013, vol. 24, # 8, p. 727 - 730
[2] Patent: CN106883118, 2017, A. Location in patent: Paragraph 0038-0042
4-DIFLUOROMETHOXY-3-METHOXY-BENZALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-DIFLUOROMETHOXY-3-METHOXY-BENZALDEHYDE manufacturers
- Product
- 4-DIFLUOROMETHOXY-3-METHOXY-BENZALDEHYDE 162401-70-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-09
- Product
- 4-Difluoromethoxy-3-Methoxy-Benzaldehyde 162401-70-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99.4%
- Supply Ability
- 100 tons
- Release date
- 2022-01-14
- Product
- 4-DIFLUOROMETHOXY-3-METHOXY-BENZALDEHYDE 162401-70-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-25