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TUFTSIN

Product Name
TUFTSIN
CAS No.
9063-57-4
Chemical Name
TUFTSIN
Synonyms
Taftsin;TUFTSIN;Tuftsin(3TFA);THR-LYS-PRO-ARG;TUFTSIN 2ACOH 4H2O;H-Thr-Lys-Pro-Arg-OH;THR-LYS-PRO-ARG 2ACOH 4H2O;L-Thr-L-Lys-L-Pro-L-Arg-OH;Tuftsin hydrate acetate salt;Tuftsin Tuftsin acetate salt hydrate
CBNumber
CB5769625
Molecular Formula
C21H40N8O6
Formula Weight
500.59
MOL File
9063-57-4.mol
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TUFTSIN Property

Density 
1.48±0.1 g/cm3(Predicted)
storage temp. 
−20°C
form 
Solid
pka
3.60±0.21(Predicted)
color 
White to off-white
Water Solubility 
Water : ≥ 160 mg/mL (319.62 mM)
Sequence
H-Thr-Lys-Pro-Arg-OH
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-7100
Product name
Tuftsin
Purity
98.40%
Packaging
5mg
Price
$60
Updated
2021/12/16
ChemScene
Product number
CS-7100
Product name
Tuftsin
Purity
98.40%
Packaging
10mg
Price
$84
Updated
2021/12/16
ChemScene
Product number
CS-7100
Product name
Tuftsin
Purity
98.40%
Packaging
25mg
Price
$114
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0003512
Product name
TUFTSIN
Purity
95.00%
Packaging
5MG
Price
$570
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0003512
Product name
TUFTSIN
Purity
95.00%
Packaging
10MG
Price
$689
Updated
2021/12/16
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TUFTSIN Chemical Properties,Usage,Production

Uses

Tuftsin is an immunostimulatory agent that induces bactericidal and tumoricidal activity by promoting phagocytosis, antigen presentation and cell migration.

Biological Activity

Tuftsin is a tetrapeptide and a macrophage/microglia activator.

in vitro

Tuftsin is a tetrapeptide, Thr-Lys-Pro-Arg, which resides in the Fc-domain of the heavy chain of immunoglobulin G. Tuftsin possesses a broad spectrum of activities related primarily to the immune system function and exerts on phagocytic cells, notably on macrophages. Tuftsin's capacity to augment cellular activation is mediated by specific receptors that are identified, characterized, and recently isolated from rabbit peritoneal granulocytes. Tuftsin, a macrophage/microglial activator, dramatically improves the clinical course of experimental autoimmune encephalomyelitis (EAE), a well-established animal model for MS. Tuftsin administration correlates with upregulation of the immunosuppressive Helper-2 Tcell (Th2) cytokine transcription factor GATA-3. Tuftsin promotes phagocytic activity for cells of monocytic origin, such as neutrophils, macrophages and microglia, all of which are thought to express Tuftsin receptors.

target

Human Endogenous Metabolite

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TUFTSIN Preparation Products And Raw materials

Raw materials

Preparation Products

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TUFTSIN Suppliers

China 101 Germany 3 Japan 3 Switzerland 1 United Kingdom 1 United States 13 Global 122
CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
--
Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
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View Lastest Price from TUFTSIN manufacturers

Career Henan Chemical Co
Product
TUFTSIN 9063-57-4
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2020-03-05

9063-57-4, TUFTSINRelated Search:

(3,4-DEHYDRO-PRO3)-TUFTSIN (LYS(Z)2)-TUFTSIN TUFTSIN P-AMINOPHENYLACETYL-THR-LYS-PRO-ARG TUFTSIN ACETATE SALT

  • TUFTSIN
  • TUFTSIN 2ACOH 4H2O
  • THR-LYS-PRO-ARG
  • THR-LYS-PRO-ARG 2ACOH 4H2O
  • Tuftsin hydrate acetate salt
  • L-Thr-L-Lys-L-Pro-L-Arg-OH
  • Taftsin
  • Tuftsin Tuftsin acetate salt hydrate
  • H-Thr-Lys-Pro-Arg-OH
  • Tuftsin Tuftsin acetate salt hydrate, ≥97% (HPLC)
  • Tuftsin(3TFA)
  • L-Arginine, L-threonyl-L-lysyl-L-prolyl-
  • 9063-57-4
  • C21H40N8O6
  • Peptide