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TUFTSIN

Product Name
TUFTSIN
CAS No.
9063-57-4
Chemical Name
TUFTSIN
Synonyms
Taftsin;TUFTSIN;Tuftsin(3TFA);THR-LYS-PRO-ARG;TUFTSIN 2ACOH 4H2O;H-Thr-Lys-Pro-Arg-OH;THR-LYS-PRO-ARG 2ACOH 4H2O;L-Thr-L-Lys-L-Pro-L-Arg-OH;Tuftsin hydrate acetate salt;Tuftsin Tuftsin acetate salt hydrate
CBNumber
CB5769625
Molecular Formula
C21H40N8O6
Formula Weight
500.59
MOL File
9063-57-4.mol
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TUFTSIN Property

Density 
1.48±0.1 g/cm3(Predicted)
storage temp. 
−20°C
pka
3.60±0.21(Predicted)
Water Solubility 
Water : ≥ 160 mg/mL (319.62 mM)
Sequence
H-Thr-Lys-Pro-Arg-OH
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-7100
Product name
Tuftsin
Purity
98.40%
Packaging
5mg
Price
$60
Updated
2021/12/16
ChemScene
Product number
CS-7100
Product name
Tuftsin
Purity
98.40%
Packaging
10mg
Price
$84
Updated
2021/12/16
ChemScene
Product number
CS-7100
Product name
Tuftsin
Purity
98.40%
Packaging
25mg
Price
$114
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0003512
Product name
TUFTSIN
Purity
95.00%
Packaging
5MG
Price
$570
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0003512
Product name
TUFTSIN
Purity
95.00%
Packaging
10MG
Price
$689
Updated
2021/12/16
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TUFTSIN Chemical Properties,Usage,Production

Uses

Tuftsin is an immunostimulatory agent that induces bactericidal and tumoricidal activity by promoting phagocytosis, antigen presentation and cell migration.

Biological Activity

Tuftsin is a tetrapeptide and a macrophage/microglia activator.

in vitro

Tuftsin is a tetrapeptide, Thr-Lys-Pro-Arg, which resides in the Fc-domain of the heavy chain of immunoglobulin G. Tuftsin possesses a broad spectrum of activities related primarily to the immune system function and exerts on phagocytic cells, notably on macrophages. Tuftsin's capacity to augment cellular activation is mediated by specific receptors that are identified, characterized, and recently isolated from rabbit peritoneal granulocytes. Tuftsin, a macrophage/microglial activator, dramatically improves the clinical course of experimental autoimmune encephalomyelitis (EAE), a well-established animal model for MS. Tuftsin administration correlates with upregulation of the immunosuppressive Helper-2 Tcell (Th2) cytokine transcription factor GATA-3. Tuftsin promotes phagocytic activity for cells of monocytic origin, such as neutrophils, macrophages and microglia, all of which are thought to express Tuftsin receptors.

target

Human Endogenous Metabolite

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TUFTSIN Preparation Products And Raw materials

Raw materials

Preparation Products

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TUFTSIN Suppliers

MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
Creative Peptides
Tel
Email
info@creative-peptides.com
Country
United States
ProdList
6084
Advantage
56
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19743
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52927
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354
Email
support@targetmol.com
Country
United States
ProdList
19973
Advantage
58
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View Lastest Price from TUFTSIN manufacturers

Career Henan Chemical Co
Product
TUFTSIN 9063-57-4
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2020-03-05

9063-57-4, TUFTSINRelated Search:


  • TUFTSIN
  • TUFTSIN 2ACOH 4H2O
  • THR-LYS-PRO-ARG
  • THR-LYS-PRO-ARG 2ACOH 4H2O
  • Tuftsin hydrate acetate salt
  • L-Thr-L-Lys-L-Pro-L-Arg-OH
  • Taftsin
  • Tuftsin Tuftsin acetate salt hydrate
  • H-Thr-Lys-Pro-Arg-OH
  • Tuftsin Tuftsin acetate salt hydrate, ≥97% (HPLC)
  • Tuftsin(3TFA)
  • L-Arginine, L-threonyl-L-lysyl-L-prolyl-
  • 9063-57-4
  • C21H40N8O6
  • Peptide