ETHYL 2-CYANOPYRIDINE-3-CARBOXYLATE

Product Name: ETHYL 2-CYANOPYRIDINE-3-CARBOXYLATE
CAS No.: 75358-90-6
Chemical Name: ETHYL 2-CYANOPYRIDINE-3-CARBOXYLATE
Synonyms: ethyl 2-cyanonicotinate;Ethyl 2-cyanonicotinate 97+%;2-Cyano-nicotinic acid ethyl ester;ETHYL 2-CYANOPYRIDINE-3-CARBOXYLATE;Ethyl 2-cyanopyridine-3-carboxylate 97%;3-(Ethoxycarbonyl)-2-pyridinecarbonitrile;2-cyano-3-pyridinecarboxylic acid ethyl ester;2-Cyanopyridine-3-carboxylic acid ethyl ester;3-Pyridinecarboxylic acid, 2-cyano-, ethyl ester
CBNumber: CB5770771
Molecular Formula: C9H8N2O2
Formula Weight: 176.17
MOL File: 75358-90-6.mol

More

Less

ETHYL 2-CYANOPYRIDINE-3-CARBOXYLATE Property

Melting point:: 35-40°C
Boiling point:: 185-195 °C(Press: 12 Torr)
Density: 1.21
storage temp.: 2-8°C
pka: -2.25±0.10(Predicted)
form: solid
Appearance: Off-white to light yellow Solid

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 36/37/39
WGK Germany: 3
HS Code: 2933399990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 791237
Product name: Ethyl 2-cyanopyridine-3-carboxylate
Purity: 97%
Packaging: 250mg
Price: $72.3
Updated: 2023/06/20

TRC

Product number: B126370
Product name: ethyl2-cyanonicotinate
Packaging: 50mg
Price: $60
Updated: 2021/12/16

AK Scientific

Product number: W8273
Product name: Ethyl2-cyanonicotinate
Packaging: 250mg
Price: $120
Updated: 2021/12/16

Activate Scientific

Product number: AS16238
Product name: Ethyl2-cyanonicotinate
Purity: 97+%
Packaging: 5G
Price: $420
Updated: 2021/12/16

Matrix Scientific

Product number: 139109
Product name: Ethyl 2-cyanonicotinate
Purity: 95%+
Packaging: 5g
Price: $1174
Updated: 2021/12/16

More

Less

ETHYL 2-CYANOPYRIDINE-3-CARBOXYLATE Chemical Properties,Usage,Production

Synthesis

557-21-1

1452-94-4

75358-90-6

To a solution of ethyl 2-chloropyridine-3-carboxylate (15.0 g, 81 mmol) in anhydrous N,N-dimethylacetamide (75 mL) was added zinc cyanide (5.71 g, 48.6 mmol), tris(dibenzylideneacetone)dipalladium (742 mg, 0.81 mmol), zinc powder (636 mg, 9.72 mmol), and 1,1'-bis(diphenylphosphinyl ) ferrocene (898 mg, 1.62 mmol). The reaction mixture was heated and stirred at 120 °C for 1 hour. After completion of the reaction, the mixture was cooled to room temperature and then partitioned between water (300 mL) and ether (150 mL). The organic and aqueous phases were separated by Celite filtration of the mixture. The aqueous phase was further extracted with ether (2 x 100 mL), all ether layers were combined, washed with saturated sodium chloride solution, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give ethyl 2-cyanonicotinate (14.26 g, 100% yield).

References

[1] Patent: WO2004/46133, 2004, A1. Location in patent: Page 31

ETHYL 2-CYANOPYRIDINE-3-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

ETHYL 2-CYANOPYRIDINE-3-CARBOXYLATE Suppliers

China 45 India 1 Switzerland 1 United Kingdom 2 United States 10 Global 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 7247
Advantage: 62

Shanghai potentpharm CO.,Ltd

Tel: 13524892556
Fax: (86) 21 51969655， QQ： 263541193
Email: sales-cn@potentpharm.com
Country: China
ProdList: 1011
Advantage: 55

SynAsst Chemical.

Tel: 021-60343070
Fax: 021-35122006
Country: China
ProdList: 12740
Advantage: 55

ShangHai AmK Pharmaceutical Technology Co., Ltd.

Tel: 微信 17321281695 18019252918
Fax: 17321281695
Email: sale@amkchem.com
Country: China
ProdList: 15136
Advantage: 55

Shanghai Yongye Biotechnology Co., Ltd.

Tel: 86-021-61559134 15921386130
Fax: 021-55068248
Email: 3423497944@qq.com
Country: China
ProdList: 8144
Advantage: 55

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 16679
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

NovoChemy Ltd.

Tel: 86-(0)21-31261262 373522135
Fax: 86-(0)21-33250524
Email: sales@novochemy.com
Country: China
ProdList: 6498
Advantage: 58

ShangHai Movin Pharmaceutical Co., Ltd.

Tel: 13681854265
Email: info@moenpharm.com
Country: China
ProdList: 480
Advantage: 55

75358-90-6, ETHYL 2-CYANOPYRIDINE-3-CARBOXYLATERelated Search:

ETHYL STEARATE ETHYL 3-CYANOPYRIDINE-2-CARBOXYLATE Ethyl 2-cyanopyridine-4-carboxylate ,97%,ETHYL 2-CYANOPYRIDINE-4-CARBOXYLATE ethyl 6-cyanopyridine-3-carboxylate ethyl 6-cyanopyridine-2-carboxylate 3-(HYDROXYMETHYL)-2-PYRIDINECARBONITRILE TERT-BUTYL-2-CYANONICOTINATE 3-Methylpicolinonitrile 2-CYANO-3-PYRIDINECARBOXYLIC ACID METHYL ESTER ETHYL 2-CYANOPYRIDINE-3-CARBOXYLATE 2-CYANOPYRIDINE-3-CARBOXYLIC ACID 3-FORMYL-2-PYRIDINECARBONITRILE

ethyl 2-cyanonicotinate

3-(Ethoxycarbonyl)-2-pyridinecarbonitrile

2-Cyanopyridine-3-carboxylic acid ethyl ester

2-cyano-3-pyridinecarboxylic acid ethyl ester

ETHYL 2-CYANOPYRIDINE-3-CARBOXYLATE

Ethyl 2-cyanonicotinate 97+%

2-Cyano-nicotinic acid ethyl ester

3-Pyridinecarboxylic acid, 2-cyano-, ethyl ester

Ethyl 2-cyanopyridine-3-carboxylate 97%

75358-90-6