3-Methylpicolinonitrile
- Product Name
- 3-Methylpicolinonitrile
- CAS No.
- 20970-75-6
- Chemical Name
- 3-Methylpicolinonitrile
- Synonyms
- 2-CYANO-3-METHYLPYRIDINE;2-CYANO-3-PICOLINE;3-METHYL-2-PYRIDINECARBONITRILE;2-Cyanopicoline;2-Cyano-3-methyL;2-Cyano-B-picoline;3-Methylpicolinonitr;Cyano-3-methylpyridine;3-METHYLPICOLINONITRILE;2-cyno,3-Methyl pyridine
- CBNumber
- CB6256294
- Molecular Formula
- C7H6N2
- Formula Weight
- 118.14
- MOL File
- 20970-75-6.mol
3-Methylpicolinonitrile Property
- Melting point:
- 83-87 °C(lit.)
- Boiling point:
- 141°C 38mm
- Density
- 1.1151 (rough estimate)
- refractive index
- 1.5500 (estimate)
- Flash point:
- 115°C
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- -0.03±0.10(Predicted)
- form
- Crystalline Powder
- color
- Light beige
- BRN
- 112001
- CAS DataBase Reference
- 20970-75-6(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-36/37
- RIDADR
- 3439
- WGK Germany
- 3
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29333999
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H301Toxic if swalloed
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 512737
- Product name
- 3-Methylpicolinonitrile
- Purity
- 98%
- Packaging
- 5g
- Price
- $49.7
- Updated
- 2023/01/07
- Product number
- C1410
- Product name
- 2-Cyano-3-methylpyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $16
- Updated
- 2025/07/31
- Product number
- C1410
- Product name
- 2-Cyano-3-methylpyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $37
- Updated
- 2025/07/31
- Product number
- M332970
- Product name
- 3-Methylpicolinonitrile
- Packaging
- 5g
- Price
- $45
- Updated
- 2021/12/16
- Product number
- JK243599
- Product name
- 2-Cyano-3-methylpyridine
- Purity
- 98%
- Packaging
- 5g
- Price
- $46
- Updated
- 2021/12/16
3-Methylpicolinonitrile Chemical Properties,Usage,Production
Chemical Properties
light beige crystalline powder
Uses
3-Methylpicolinonitrile is a useful chemical reagent. It has been used in the synthesis of, triazolo[1,5-c]pyrimidines as potential antiasthma agents; ?s-tetrazine derivatives as anti-tumor agents.
Synthesis
1003-73-2
20970-75-6
II-1-1: Synthesis of 2-cyano-3-methylpyridine 10.9 g (0.1 mol) of 3-methylpyridine-N-oxide was mixed with 12.6 g (0.1 mol) of dimethyl sulfate and the reaction was stirred at 70-75°C for 2 hours. Subsequently, a solution prepared from 13.0 g (0.2 mol) potassium cyanide dissolved in 10-40 mL of water was slowly added dropwise to the reaction system while maintaining stirring. After the dropwise addition was completed, the reaction mixture was continued to be stirred at the same temperature for 1 hour and then at room temperature for another 1 hour. Upon completion of the reaction, it was diluted with 150 mL of water and extracted with dichloromethane. The organic phases were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure. The resulting crude product was purified by silica gel column chromatography (eluent ratio: ethyl acetate/hexane = 2:8 to 3:7, 2:8 for the second time), and finally recrystallized from hexane to give 2.20 g of colorless solid product in 18.6% yield. The melting point of the product was 82.5-83.5 °C. IR (KBr, cm-1): 2210, 1560.
References
[1] Patent: US5219847, 1993, A
[2] Chemical and Pharmaceutical Bulletin, 1959, vol. 7, p. 925,928
3-Methylpicolinonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
3-Methylpicolinonitrile Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 400-0066400 13621662912
- Fax
- 021-55660885
- sales@jonln.com
- Country
- China
- ProdList
- 1995
- Advantage
- 65
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- +86 351 7031519
- Fax
- +86 351 7031519
- sales@RHFChem.com
- Country
- China
- ProdList
- 2338
- Advantage
- 56
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 0311-89250318 031166536426
- Fax
- 4000311741
- master@sjzsdyn.com
- Country
- China
- ProdList
- 2807
- Advantage
- 65
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
View Lastest Price from 3-Methylpicolinonitrile manufacturers
- Product
- 3-Methylpicolinonitrile 20970-75-6
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-12-02
- Product
- 3-Methylpicolinonitrile 20970-75-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-13
- Product
- 2-Cyano-3-methylpyridine 20970-75-6
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99.1%
- Supply Ability
- 100 tons
- Release date
- 2022-01-26