2-CYANO-4-METHYLPYRIDINE

Product Name: 2-CYANO-4-METHYLPYRIDINE
CAS No.: 1620-76-4
Chemical Name: 2-CYANO-4-METHYLPYRIDINE
Synonyms: 4-Methylpicolinonitrile;2-CYANO-4-PICOLINE;2-CYANO-4-METHYLPYRIDINE;2-Cyano-4-methylpyridine >2-Cyano-4-methylpyridine ,98%;4-Methylpyridin-2-carbonitrile;4-METHYL-2-PYRIDINECARBONITRILE;4-METHYLPYRIDINE-2-CARBONITRILE;2-Pyridinecarbonitrile, 4-methyl-;4-Methylpyridine-2-carbonitrile 97%
CBNumber: CB8707644
Molecular Formula: C7H6N2
Formula Weight: 118.14
MOL File: 1620-76-4.mol

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2-CYANO-4-METHYLPYRIDINE Property

Melting point:: 83-87 °C
Boiling point:: 145-148°C 38mm
Density: 1.08±0.1 g/cm3(Predicted)
Flash point:: 145-148°C/38mm
storage temp.: Inert atmosphere,Room Temperature
pka: 0.35±0.10(Predicted)
form: powder to crystal
color: White to Gray to Brown
Water Solubility: Slightly soluble in water.
BRN: 110753
InChI: InChI=1S/C7H6N2/c1-6-2-3-9-7(4-6)5-8/h2-4H,1H3
InChIKey: LQAWSWUFSHYCHP-UHFFFAOYSA-N
SMILES: C1(C#N)=NC=CC(C)=C1
CAS DataBase Reference: 1620-76-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 20/21/22-41-37/38-22-36/37/38
Safety Statements: 22-36/37-39-26-36
RIDADR: 3276
WGK Germany: 3
HazardClass: 6.1
PackingGroup: III
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 673463
Product name: 4-Methyl-2-pyridinecarbonitrile
Purity: 97%
Packaging: 1g
Price: $153
Updated: 2023/06/20

Sigma-Aldrich

Product number: 673463
Product name: 4-Methyl-2-pyridinecarbonitrile
Purity: 97%
Packaging: 5g
Price: $500
Updated: 2023/06/20

TCI Chemical

Product number: C2603
Product name: 2-Cyano-4-methylpyridine
Purity: >98.0%(GC)
Packaging: 5g
Price: $79
Updated: 2025/07/31

TCI Chemical

Product number: C2603
Product name: 2-Cyano-4-methylpyridine
Purity: >98.0%(GC)
Packaging: 25g
Price: $328
Updated: 2025/07/31

TRC

Product number: M333075
Product name: 4-Methylpicolinonitrile
Packaging: 500mg
Price: $75
Updated: 2021/12/16

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2-CYANO-4-METHYLPYRIDINE Chemical Properties,Usage,Production

Chemical Properties

White to brown solid

Uses

2-Cyano-4-methylpyridine can react to produce C7H7NO2.ClH. This reaction will need reagent 6 NHCl.

Synthesis

1003-67-4

7677-24-9

1620-76-4

4-Methylpyridine-N-oxide (2.0 g, 18.3 mmol) was used as starting material and dissolved in nitroethane (25 mL). Subsequently, trimethylcyanosilane (2.0 g, 20.2 mmol) and N,N-dimethylcarbamoyl chloride (1.7 mL, 18.5 mmol) were added sequentially to this solution. The reaction mixture was stirred at room temperature for 5 days. Upon completion of the reaction, the mixture was concentrated under reduced pressure, combined with saturated aqueous sodium bicarbonate solution and extracted with ethyl acetate. The organic phases were combined and the solvent was removed by evaporation under reduced pressure. The resulting crystals were collected by filtration, washed with diisopropyl ether and dried to afford the target product 2-cyano-4-methylpyridine (0.91 g, 42% yield). The product was characterized by 1H-NMR (CDCl3), δ: 2.43 (3H, s), 7.33 (1H, d, J = 5.1 Hz), 7.53 (1H, s), 8.57 (1H, d, J = 4.8 Hz).

References

[1] Journal of Organic Chemistry, 1983, vol. 48, # 8, p. 1375 - 1377
[2] Journal of Organic Chemistry, 2013, vol. 78, # 16, p. 8054 - 8064
[3] Synthesis, 1983, # 4, p. 316 - 319
[4] Advanced Synthesis and Catalysis, 2013, vol. 355, # 5, p. 947 - 956
[5] Journal of the American Chemical Society, 1990, vol. 112, # 17, p. 6248 - 6254

2-CYANO-4-METHYLPYRIDINE Preparation Products And Raw materials

Raw materials

4-Methylpyridine Hydrogen peroxide Acetic acid POTASSIUM CYANIDE Dimethyl sulfate

Preparation Products

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2-CYANO-4-METHYLPYRIDINE Suppliers

Americas 1 Canada 1 China 178 Europe 1 France 1 Germany 7 India 17 Japan 2 Switzerland 1 United Kingdom 12 United States 35 Global 256

Jinan LuoHe PharmaTech Co., Ltd.

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View Lastest Price from 2-CYANO-4-METHYLPYRIDINE manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2-CYANO-4-METHYLPYRIDINE 1620-76-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-05-29

Shaanxi Dideu Medichem Co. Ltd

Product: 2-CYANO-4-METHYLPYRIDINE 1620-76-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-13

Henan Fengda Chemical Co., Ltd

Product: 2-CYANO-4-METHYLPYRIDINE 1620-76-4
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-08

1620-76-4, 2-CYANO-4-METHYLPYRIDINERelated Search:

6-Methylpyridine-2-carbonitrile 2-CYANO-5-METHYLPYRIDINE,2-CYANO-5-METHYLPYRIDINE (2-CYANO-5-PICOLINE) 5-Bromo-2-pyridinecarbonitrile 4-Bromomethyl-2-cyanobiphenyl 5-Bromo-6-methyl-2-pyridinecarbonitrile 4-CHLORO-PYRIDINE-2-CARBONITRILE 2-Cyano-4-fluoropyridine 2-Cyano-5-fluoropyridine 3-Bromo-2-cyanopyridine (5-TRIFLUOROMETHYL-PYRIDIN-2-YL)-ACETONITRILE 2-Cyano-5-nitropyridine 5-Chloro-2-cyanopyridine 5-BROMO-4-METHYL-PYRIDINE-2-CARBONITRILE 2-CHLORO-3-CYANO-6-METHYLPYRIDINE,2-CHLORO-3-CYANO-6-METHYLPYRIDINE 99% 3-CYANO-5-METHYLPYRIDINE 3-Methylpicolinonitrile 2-Chloro-4-methylpyridine-3-carbonitrile 2,6-DIHYDROXY-3-CYANO-4-METHYLPYRIDINE

2-CYANO-4-METHYLPYRIDINE

2-CYANO-4-PICOLINE

4-METHYLPYRIDINE-2-CARBONITRILE

4-METHYL-2-PYRIDINECARBONITRILE

4-Methylpicolinonitrile

2-CYANO-4-METHYLPYRIDINE (2-CYANO-4-PICOLINE)

2-Cyano-4-methylpyridine, 4-Methyl-2-cyanopyridine

2-Cyano-4-methylpyridine ,98%

4-Methylpyridine-2-carbonitrile 97%

2-Cyano-4-methylpyridine, 4-Methylpicolinonitrile

2-Cyano-4-methylpyridine &gt

2-Pyridinecarbonitrile, 4-methyl-

2-CYANO-4-METHYLPYRIDINE ISO 9001：2015 REACH

4-Methylpyridin-2-carbonitrile

1620-76-4

Building Blocks

C7 and C8

Heterocyclic Building Blocks

Pyridines

Heterocycle-Pyridine series

Pyridines

Heterocyclic Compounds