ChemicalBook > CAS DataBase List > 2-CYANO-4-METHYLPYRIDINE

2-CYANO-4-METHYLPYRIDINE

Product Name
2-CYANO-4-METHYLPYRIDINE
CAS No.
1620-76-4
Chemical Name
2-CYANO-4-METHYLPYRIDINE
Synonyms
4-Methylpicolinonitrile;2-CYANO-4-PICOLINE;2-CYANO-4-METHYLPYRIDINE;2-Cyano-4-methylpyridine >2-Cyano-4-methylpyridine ,98%;4-Methylpyridin-2-carbonitrile;4-METHYL-2-PYRIDINECARBONITRILE;4-METHYLPYRIDINE-2-CARBONITRILE;2-Pyridinecarbonitrile, 4-methyl-;4-Methylpyridine-2-carbonitrile 97%
CBNumber
CB8707644
Molecular Formula
C7H6N2
Formula Weight
118.14
MOL File
1620-76-4.mol
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2-CYANO-4-METHYLPYRIDINE Property

Melting point:
83-87 °C
Boiling point:
145-148°C 38mm
Density 
1.08±0.1 g/cm3(Predicted)
Flash point:
145-148°C/38mm
storage temp. 
Inert atmosphere,Room Temperature
pka
0.35±0.10(Predicted)
form 
powder to crystal
color 
White to Gray to Brown
Water Solubility 
Slightly soluble in water.
BRN 
110753
InChI
InChI=1S/C7H6N2/c1-6-2-3-9-7(4-6)5-8/h2-4H,1H3
InChIKey
LQAWSWUFSHYCHP-UHFFFAOYSA-N
SMILES
C1(C#N)=NC=CC(C)=C1
CAS DataBase Reference
1620-76-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
20/21/22-41-37/38-22-36/37/38
Safety Statements 
22-36/37-39-26-36
RIDADR 
3276
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
III
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
673463
Product name
4-Methyl-2-pyridinecarbonitrile
Purity
97%
Packaging
1g
Price
$153
Updated
2023/06/20
Sigma-Aldrich
Product number
673463
Product name
4-Methyl-2-pyridinecarbonitrile
Purity
97%
Packaging
5g
Price
$500
Updated
2023/06/20
TCI Chemical
Product number
C2603
Product name
2-Cyano-4-methylpyridine
Purity
>98.0%(GC)
Packaging
5g
Price
$79
Updated
2025/07/31
TCI Chemical
Product number
C2603
Product name
2-Cyano-4-methylpyridine
Purity
>98.0%(GC)
Packaging
25g
Price
$328
Updated
2025/07/31
TRC
Product number
M333075
Product name
4-Methylpicolinonitrile
Packaging
500mg
Price
$75
Updated
2021/12/16
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2-CYANO-4-METHYLPYRIDINE Chemical Properties,Usage,Production

Chemical Properties

White to brown solid

Uses

2-Cyano-4-methylpyridine can react to produce C7H7NO2.ClH. This reaction will need reagent 6 NHCl.

Synthesis

1003-67-4

7677-24-9

1620-76-4

4-Methylpyridine-N-oxide (2.0 g, 18.3 mmol) was used as starting material and dissolved in nitroethane (25 mL). Subsequently, trimethylcyanosilane (2.0 g, 20.2 mmol) and N,N-dimethylcarbamoyl chloride (1.7 mL, 18.5 mmol) were added sequentially to this solution. The reaction mixture was stirred at room temperature for 5 days. Upon completion of the reaction, the mixture was concentrated under reduced pressure, combined with saturated aqueous sodium bicarbonate solution and extracted with ethyl acetate. The organic phases were combined and the solvent was removed by evaporation under reduced pressure. The resulting crystals were collected by filtration, washed with diisopropyl ether and dried to afford the target product 2-cyano-4-methylpyridine (0.91 g, 42% yield). The product was characterized by 1H-NMR (CDCl3), δ: 2.43 (3H, s), 7.33 (1H, d, J = 5.1 Hz), 7.53 (1H, s), 8.57 (1H, d, J = 4.8 Hz).

References

[1] Journal of Organic Chemistry, 1983, vol. 48, # 8, p. 1375 - 1377
[2] Journal of Organic Chemistry, 2013, vol. 78, # 16, p. 8054 - 8064
[3] Synthesis, 1983, # 4, p. 316 - 319
[4] Advanced Synthesis and Catalysis, 2013, vol. 355, # 5, p. 947 - 956
[5] Journal of the American Chemical Society, 1990, vol. 112, # 17, p. 6248 - 6254

2-CYANO-4-METHYLPYRIDINE Preparation Products And Raw materials

Raw materials

4-Methylpyridine Hydrogen peroxide Acetic acid POTASSIUM CYANIDE Dimethyl sulfate

Preparation Products

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2-CYANO-4-METHYLPYRIDINE Suppliers

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View Lastest Price from 2-CYANO-4-METHYLPYRIDINE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-CYANO-4-METHYLPYRIDINE 1620-76-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-05-29
Shaanxi Dideu Medichem Co. Ltd
Product
2-CYANO-4-METHYLPYRIDINE 1620-76-4
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-13
Henan Fengda Chemical Co., Ltd
Product
2-CYANO-4-METHYLPYRIDINE 1620-76-4
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08

1620-76-4, 2-CYANO-4-METHYLPYRIDINERelated Search:

6-Methylpyridine-2-carbonitrile 2-CYANO-5-METHYLPYRIDINE,2-CYANO-5-METHYLPYRIDINE (2-CYANO-5-PICOLINE) 5-Bromo-2-pyridinecarbonitrile 4-Bromomethyl-2-cyanobiphenyl 5-Bromo-6-methyl-2-pyridinecarbonitrile 4-CHLORO-PYRIDINE-2-CARBONITRILE 2-Cyano-4-fluoropyridine 2-Cyano-5-fluoropyridine 3-Bromo-2-cyanopyridine (5-TRIFLUOROMETHYL-PYRIDIN-2-YL)-ACETONITRILE 2-Cyano-5-nitropyridine 5-Chloro-2-cyanopyridine 5-BROMO-4-METHYL-PYRIDINE-2-CARBONITRILE 2-CHLORO-3-CYANO-6-METHYLPYRIDINE,2-CHLORO-3-CYANO-6-METHYLPYRIDINE 99% 3-CYANO-5-METHYLPYRIDINE 3-Methylpicolinonitrile 2-Chloro-4-methylpyridine-3-carbonitrile 2,6-DIHYDROXY-3-CYANO-4-METHYLPYRIDINE

  • 2-CYANO-4-METHYLPYRIDINE
  • 2-CYANO-4-PICOLINE
  • 4-METHYLPYRIDINE-2-CARBONITRILE
  • 4-METHYL-2-PYRIDINECARBONITRILE
  • 4-Methylpicolinonitrile
  • 2-CYANO-4-METHYLPYRIDINE (2-CYANO-4-PICOLINE)
  • 2-Cyano-4-methylpyridine, 4-Methyl-2-cyanopyridine
  • 2-Cyano-4-methylpyridine ,98%
  • 4-Methylpyridine-2-carbonitrile 97%
  • 2-Cyano-4-methylpyridine, 4-Methylpicolinonitrile
  • 2-Cyano-4-methylpyridine &gt
  • 2-Pyridinecarbonitrile, 4-methyl-
  • 2-CYANO-4-METHYLPYRIDINE ISO 9001：2015 REACH
  • 4-Methylpyridin-2-carbonitrile
  • 1620-76-4
  • Building Blocks
  • C7 and C8
  • Heterocyclic Building Blocks
  • Pyridines
  • Heterocycle-Pyridine series
  • Pyridines
  • Heterocyclic Compounds