6-Methylpyridine-2-carbonitrile

Product Name: 6-Methylpyridine-2-carbonitrile
CAS No.: 1620-75-3
Chemical Name: 6-Methylpyridine-2-carbonitrile
Synonyms: NSC 26022;6-Cyanopicoline;6-Cyano-2-picoline;Cyano-6-Methylpyrid;6-Methyl-2-cyanopyridine;2-Methyl-6-cyanopyridine;6-Cyano-2-methylpyridine;2-Cyano-6-methlypyridine;2-CYANO-6-METHYLPYRIDINE;6-METHYL PICOLINONITRILE
CBNumber: CB6682721
Molecular Formula: C7H6N2
Formula Weight: 118.14
MOL File: 1620-75-3.mol

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6-Methylpyridine-2-carbonitrile Property

Melting point:: 70-74 °C(lit.)
Boiling point:: 0°C
Density: 1.08±0.1 g/cm3(Predicted)
Flash point:: 0°C
storage temp.: Inert atmosphere,Room Temperature
solubility: Dichloromethane, Hexane
pka: 0.40±0.10(Predicted)
form: Solid
color: Off-white
InChI: 1S/C7H6N2/c1-6-3-2-4-7(5-8)9-6/h2-4H,1H3
InChIKey: CMADFEQMYFNYCF-UHFFFAOYSA-N
SMILES: Cc1cccc(n1)C#N
CAS DataBase Reference: 1620-75-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
RIDADR: UN 3439 6.1/PG III
WGK Germany: 3
HazardClass: 6.1
PackingGroup: III
HS Code: 29333990
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 125385
Product name: 6-Methyl-2-pyridinecarbonitrile
Purity: 97%
Packaging: 5g
Price: $114
Updated: 2023/06/20

TCI Chemical

Product number: C3025
Product name: 2-Cyano-6-methylpyridine
Purity: >98.0%(GC)
Packaging: 1g
Price: $44
Updated: 2026/03/19

TCI Chemical

Product number: C3025
Product name: 2-Cyano-6-methylpyridine
Purity: >98.0%(GC)
Packaging: 5g
Price: $172
Updated: 2026/03/19

TRC

Product number: C981945
Product name: 6-Cyano-2-methylpyridine
Packaging: 25g
Price: $215
Updated: 2021/12/16

AK Scientific

Product number: X7088
Product name: 2-Cyano-6-methylpyridine
Packaging: 1g
Price: $14
Updated: 2021/12/16

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6-Methylpyridine-2-carbonitrile Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

6-Methyl-2-pyridinecarbonitrile was used in the synthesis of zinc complexes bearing N,N′-bidentate entiopure ligands.

Uses

Intermediate in the preparation of selective cyclooxygenase-2 inhibitors and calcium antagonists

Synthesis Reference(s)

The Journal of Organic Chemistry, 48, p. 1375, 1983 DOI: 10.1021/jo00156a053

Synthesis

Steps in the preparation of 6-methyl-2-pyridinecarbonitrile:

Mix hydrobromic acid and 2-amino-6-methylpyridine under stirring conditions, keep warm; then cool the solution, add bromine Br2 to the solution, and then keep this reaction at a low temperature; then add aqueous sodium nitrite to the solution at this low temperature, and then react; at the end of the reaction cool the reaction solution down, adjust the pH with alkali, and then distill by water vapor distillation to obtain 2-bromo-6-methylpyridine; add cuprous cyanide and Lithium bromide was added to DMF with a mass of 2-5 times the mass of 2-bromo-6-methylpyridine, and then the solution was heated, and the reaction was kept warm after the addition of 2-bromo-6-methylpyridine; at the end of the reaction, the solution was cooled down, water was added, and then the product was obtained by water vapor distillation.

6-Methylpyridine-2-carbonitrile Preparation Products And Raw materials

Raw materials

Copper(I) Cyanide N,N-Dimethylformamide 2-Amino-6-methylpyridine Ferric chloride Sodium nitrite Hydrogen bromide Bromine Sodium hydroxide

Preparation Products

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6-Methylpyridine-2-carbonitrile Suppliers

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View Lastest Price from 6-Methylpyridine-2-carbonitrile manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 6-Methylpicolinonitrile 1620-75-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-02-17

Henan Fengda Chemical Co., Ltd

Product: 6-Methylpyridine-2-carbonitrile 1620-75-3
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-08

Career Henan Chemical Co

Product: 6-Methylpyridine-2-carbonitrile 1620-75-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg;10kg;100kg
Release date: 2019-08-29

1620-75-3, 6-Methylpyridine-2-carbonitrileRelated Search:

Azamethiphos 5-Amino-2-methylpyridine 2-CYANO-4-METHYLPYRIDINE 3-Methylpicolinonitrile 2,5-Dimethylpyridine 4-Methylpyridine 3-CYANO-5-METHYLPYRIDINE 2-Cyanopyridine 2,6-Lutidine 2-Chloro-5-chloromethylpyridine 5-Bromo-2-pyridinecarbonitrile 4-Bromomethyl-2-cyanobiphenyl 2-Cyano-5-methylpyridine 5-Bromo-6-methyl-2-pyridinecarbonitrile 4-CHLORO-PYRIDINE-2-CARBONITRILE 2-Cyano-4-fluoropyridine 2-Cyano-5-fluoropyridine 3-Bromo-2-cyanopyridine

2-CYANO-6-METHYLPYRIDINE (2-CYANO-6-PICOLINE)

2-Cyano-6-methylpyridine, 2-Methyl-6-cyanopyridine, 6-Methylpicolinonitrile

6-Methyl-2-pyridinecarbonitrile ,98%

2-Cyano-6-methlypyridine

6-Cyano-2-methylpyridine

2-Methyl-6-cyanopyridine

6-Methyl-2-cyanopyridine

NSC 26022

6-METHYL-PYRIDINE-2-CARBONITRILE

6-METHYL PICOLINONITRILE

2-CYANO-6-METHYLPYRIDINE

Cyano-6-Methylpyrid

2-Cyano-5-methly pyridine

6-methyl-2-pyridinecarbonitrile

2-Cyano-6-methylpyridine, 6-Methylpicolinonitrile

6-Methyl-pyridine-2-carbonitrile，6-Cyanopicoline，6-Methyl-2-pyridinecarbonitrile，2-Cyano-6-methylpyridine

2-CYANO-6-METHYLPYRIDINE / 6-METHYL-2-PYRIDINECARBONITRILE

2-CYANO-6-METHYLPYRIDINE 6-METHYL-PYRIDINE-2-CARBONITRILE

6-Methylpyridine-2-carbonitrile 97%

2-Pyridinecarbonitrile, 6-methyl-

2-Methoxy-5-Nitro-7-Picoline

6-Cyano-2-picoline

6-Methylpyridine-2-carbonitrile ISO 9001：2015 REACH

6-Cyanopicoline

6-methyl-2-pyridinitrile

1620-75-3

C7 and C8

Building Blocks

Pyridines

Heterocyclic Building Blocks

Heterocycle-Pyridine series

Aromatics

Heterocycles

Intermediates

Pyridine series