METHYL 4-FLUOROBENZOYLACETATE

Product Name: METHYL 4-FLUOROBENZOYLACETATE
CAS No.: 63131-29-3
Chemical Name: METHYL 4-FLUOROBENZOYLACETATE
Synonyms: METHYL 4-FLUOROBENZOYLACETATE;Methyle4-fluorobenzoylacetate;Methyl 4'-fluorobenzoylacetate;methyl 4'-fluorobenzoylacetates;Methyl4-Fluorobenzoylacetate>Methyl4-fluorobenzoylacetate,95%;Methyl 4-fluorobenzoylacetate,99%;Methyl4- fluorobenzoylacetic acid;Methyl-2-(4-fluorobenzoyl)acetate;Methyl p-fluorobenzoylacetate, 99%
CBNumber: CB5774360
Molecular Formula: C10H9FO3
Formula Weight: 196.18
MOL File: 63131-29-3.mol

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METHYL 4-FLUOROBENZOYLACETATE Property

Boiling point:: 91°C/5mm
Density: 1.228 g/mL at 25 °C (lit.)
refractive index: n20/D 1.521(lit.)
Flash point:: >230 °F
storage temp.: Sealed in dry,Room Temperature
pka: 9.80±0.25(Predicted)
form: Liquid
color: Clear colorless to dark yellow
BRN: 3050469
InChI: 1S/C10H9FO3/c1-14-10(13)6-9(12)7-2-4-8(11)5-3-7/h2-5H,6H2,1H3
InChIKey: HGLVYXXPRSNKQN-UHFFFAOYSA-N
SMILES: COC(=O)CC(=O)c1ccc(F)cc1
CAS DataBase Reference: 63131-29-3(CAS DataBase Reference)

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Safety

Safety Statements: 23-24/25
WGK Germany: 3
HS Code: 29183000
Storage Class: 10 - Combustible liquids

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 213063
Product name: Methyl 4-fluorobenzoylacetate
Purity: 95%
Packaging: 10g
Price: $232
Updated: 2023/01/07

TCI Chemical

Product number: F0472
Product name: Methyl (4-Fluorobenzoyl)acetate
Purity: >98.0%(GC)
Packaging: 1g
Price: $66
Updated: 2025/07/31

TCI Chemical

Product number: F0472
Product name: Methyl (4-Fluorobenzoyl)acetate
Purity: >98.0%(GC)
Packaging: 5g
Price: $197
Updated: 2025/07/31

TRC

Product number: M305505
Product name: Methyl (4-Fluorobenzoyl)acetate
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: M305505
Product name: Methyl (4-Fluorobenzoyl)acetate
Packaging: 1g
Price: $75
Updated: 2021/12/16

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METHYL 4-FLUOROBENZOYLACETATE Chemical Properties,Usage,Production

Chemical Properties

clear yellow liquid

Uses

Methyl 4-fluorobenzoylacetate was used in the synthesis of:

3-amino-4-(-4-fluoro-phenyl)furazan
series of substituted coumarin derivatives, potential 5-lipoxygenase inhibitors

Synthesis

Anhydrous tetrahydrofuran (540 mL), dimethyl carbonate (235.2 g, 2.61 mol) and sodium hydrogen (130.5 g, 3.263 mol, 60%) were added to a dry reaction flask then the mixture was heated to reflux, and a solution of anhydrous tetrahydrofuran (180 mL) of p-fluoroacetophenone (180.3 g, 1.305 mol) was slowly added dropwise, the dropwise addition process was titrated over a period of 4 hours. Refluxing of the reaction solution was continued for another 0.5 h. The reaction was monitored by TLC (ethyl acetate:petroleum ether v/v=1:6, Rf=0.3) and the reaction solution was cooled to 0??C. Excess sodium hydroxide was quenched dropwise by addition of a mixture of 90 ml of methanol and 270 ml of tetrahydrofuran. The reaction solution was poured into a mixture of saturated ammonium chloride and ice, hydrochloric acid adjusted pH = 3,ethyl acetate, respectively, washed with water, saline, drying, concentrated under reduced pressure to obtain the crude product (292.9 g.100%) oil.

METHYL 4-FLUOROBENZOYLACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL 4-FLUOROBENZOYLACETATE Suppliers

Americas 1 Austria 1 Belgium 2 China 137 Egypt 1 Europe 1 Germany 6 India 8 Japan 3 Slovakia 1 Switzerland 3 United Kingdom 12 United States 32 Global 208

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View Lastest Price from METHYL 4-FLUOROBENZOYLACETATE manufacturers

Career Henan Chemical Co

Product: METHYL 4-FLUOROBENZOYLACETATE 63131-29-3
Price: US $2.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-24

63131-29-3, METHYL 4-FLUOROBENZOYLACETATERelated Search:

Methyl 4-fluorobenzoate Methyl 4-ethoxybenzoate Methyl 4-cyanobenzoate Ethyl 3-(4-fluorophenyl)-3-oxopropanoate Ethyl (pentafluorobenzoyl)acetate Ethyl 2,3,4,5-tetrafluorobenzoyl acetate Ethyl 1-ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate METHYL 4-FLUOROBENZOYLACETATE Ethyl 2,4,5-trifluorobenzoylacetate 3-(3,4-DIFLUOROPHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester 4-Fluorophenylacetic acid PHENOXYACETIC ACID Methyl phenylacetate Methyl acetate ETHYL 2,4-DIFLUOROBENZOYLACETATE Ethyl 6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate 3-OXO-3-(2,4,5-TRIFLUORO-3-METHOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER

3-(4-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID METHYL ESTER

4-FLUOROBENZOYLACETIC ACID METHYL ESTER

METHYL 4-FLUOROBENZOYLACETATE

METHYL 3-(4-FLUOROPHENYL)-3-OXOPROPIONATE

Methyl4-fluorobenzoylacetate,95%

3-(4-fluorophenyl)-3-oxopropionic aicd methyl ester

3-(4-Fluorophenyl)propionic acid methyl ester

Methyl 3-(4-fluorophenyl)-3-oxopropanoate

Methyl 3-(4-fluorophenyl)-3-oxopropanoate 98+%

methyl 4'-fluorobenzoylacetates

Methyl p-fluorobenzoylacetate, 99%

3-(p-Fluorophenyl)-3-oxopropionic acid methyl ester

3-Oxo-3-(4-fluorophenyl)propanoic acid methyl ester

3-Oxo-3-(4-fluorophenyl)propionic acid methyl ester

β-Oxo-4-fluorobenzenepropionic acid methyl ester

Methyl 4-fluorobenzoylacetate,99%

3-(4-fluorophenyl)-2-Methyl-3-oxopropanoate

Methyl4- fluorobenzoylacetic acid

3-(4-fluorophenyl)-3-keto-propionic acid methyl ester

3-(4-fluorophenyl)-3-oxopropanoic acid methyl ester

Benzenepropanoic acid, 4-fluoro-b-oxo-, Methyl ester

Methyl 4-fluorobenzoylacetate, 99% 10GR

Methyl 4-fluorobenzoylacetate, 98.5%

Methyl (4-fluorobenzoyl)acetate, Methyl 3-(4-fluorophenyl)-3-oxopropionate

Benzenepropanoic acid, 4-fluoro-.beta.-oxo-, methyl ester

Methyle4-fluorobenzoylacetate

Methyl4-Fluorobenzoylacetate&gt

Benzenepropanoic acid, 4-fluoro-β-oxo-, methyl ester

Benzenepropanoicacid,4-fluoro-β-oxo-,methylester

Methyl 4-fluoro-β-oxobenzenepropanoate

Methyl 4'-fluorobenzoylacetate

Methyl-2-(4-fluorobenzoyl)acetate

63131-29-3

FC6H4COCH2CO2CH3

ACETATE

Organic Building Blocks

Esters

C10 to C11

Carbonyl Compounds

Building Blocks

Acetics acid and esters

API intermediates

Acids and Derivatives

Carbonyl Compounds