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SULFURETIN

Product Name: SULFURETIN
CAS No.: 120-05-8
Chemical Name: SULFURETIN
Synonyms: SULFURETIN;SULPHURETIN;SULFURETIN hplc;SULFURETIN WITH HPLC;3',4',6-TRIHYDROXYAURONE;6,3',4'-TRIHYDROXYAURONE;3',4',6-Trihydroxybenzalcoumaranone;2-(3,4-dihydroxybenzylidene)-6-hydroxy-2H-benzofuran-3-one;2-(3,4-Dihydroxybenzylidene)-6-hydroxy-3(2H)-benzofuranone;(Z)-2-(3,4-Dihydroxybenzylidene)-6-hydroxybenzofuran-3(2H)-one
CBNumber: CB5774890
Molecular Formula: C15H10O5
Formula Weight: 270.24
MOL File: 120-05-8.mol

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SULFURETIN Property

Melting point:: 295°C
storage temp.: 2-8°C
solubility: Acetone: Soluble
Chloroform: Soluble
Dichloromethane: Soluble
DMSO: SolubleEthyl Acetate: Soluble
form: Solid
color: Yellow to orange
LogP: 1.980 (est)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML3002
Product name: Sulfuretin
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $151.05
Updated: 2025/07/31

Biosynth Carbosynth

Product number: FS137768
Product name: Sulfuretin
Packaging: 1mg
Price: $225
Updated: 2021/12/16

AK Scientific

Product number: 9995AJ
Product name: Sulfurein
Packaging: 2mg
Price: $320
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FS137768
Product name: Sulfuretin
Packaging: 2mg
Price: $350
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FS137768
Product name: Sulfuretin
Packaging: 5mg
Price: $550
Updated: 2021/12/16

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SULFURETIN Chemical Properties,Usage,Production

Uses

Sulfuretin inhibits the inflammatory response by suppressing the NF-κB pathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis[1]. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC50 of 13.64 μM[2].

Definition

ChEBI: Sulfuretin is a member of 1-benzofurans.

Biological Activity

Anti-adipogenic, antineoplastic activity, antioxidative stress, Anti-Inflammatory

in vivo

Sulfuretin inhibits the inflammatory responses by suppressing the NF-κB pathway in type 1 diabetes models. Sulfuretin (40 μg/kg; single intraperitoneal injection 2 h after the last OVA challenge) suppresses ovalbumin (OVA)-induced chemotaxis and airway inflammation^[1].

Animal Model:	Pathogen-free male BALB/c mice (7-8 weeks old)^[1]
Dosage:	40 μg/kg
Administration:	A single intraperitoneal injection was administered 2 h after the last OVA challenge
Result:	Suppressed OVA-induced chemotaxis and airway inflammation.

References

[1] Mi-Young Song, et al. Sulfuretin attenuates allergic airway inflammation in mice. Biochem Biophys Res Commun. 2010 Sep 10;400(1):83-8. DOI:10.1016/j.bbrc.2010.08.014
[2] Chen, H., et al. Isolation of sulfuretin and butin from Rhus verniciflua Stokes using medium-pressure liquid chromatography and their tyrosinase inhibitory effects. BioRes. 11(1), 759-771.
[3] SO YOUNG KANG Myung J O Ji Young Kang. Antiviral activities of flavonoids isolated from the bark of Rhus verniciflua stokes against fish pathogenic viruses In Vitro.[J]. Journal of Microbiology, 2012, 50 2: 293-300. DOI: 10.1007/s12275-012-2068-7

SULFURETIN Preparation Products And Raw materials

Raw materials

Preparation Products

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120-05-8, SULFURETINRelated Search:

AKOS BBS-00006136 AKOS BBS-00006112 AKOS BBS-00006130 MARITIMEIN RENGASIN-4'-O-GLUCOSIDE AKOS BBS-00006134 AKOS BBS-00006157 AUREUSIDIN-4-METHYL ETHER SULFURETIN AURORA 20031 AUREUSIDIN(RG) RENGASIN-3'-O-GLUCOSIDE

SULFURETIN

6,3',4'-TRIHYDROXYAURONE

3',4',6-TRIHYDROXYAURONE

2-(3,4-dihydroxybenzylidene)-6-hydroxy-2H-benzofuran-3-one

(Z)-2-[(3,4-dihydroxyphenyl)methylene]-6-hydroxy-2H-benzofuran-3-one

SULPHURETIN

SULFURETIN WITH HPLC

SULFURETIN hplc

(Z)-2-[(3,4-Dihydroxyphenyl)methylene]-6-hydroxy-3(2H)-benzofuranone

2-[(Z)-(3,4-Dihydroxyphenyl)methylene]-6-hydroxybenzofuran-3(2H)-one

2-(3,4-Dihydroxybenzylidene)-6-hydroxy-3(2H)-benzofuranone

3',4',6-Trihydroxybenzalcoumaranone

3(2H)-Benzofuranone, 2-[(3,4-dihydroxyphenyl)methylene]-6-hydroxy-, (2Z)-

inflammation,platelet,Allergic,Sulfuretin,Nuclear factor-kappaB,Airway,Inhibitor,aggregation,monophenolase,diphenolase,NF-κB,mutagenesis,oxidative,Nuclear factor-κB,stress,Asthma,inhibit

(Z)-2-(3,4-Dihydroxybenzylidene)-6-hydroxybenzofuran-3(2H)-one

(Z)-2-(3,4-Dihydroxybenzylidene)-6-hydroxybenzofuran-3(2H)-one , Sulfuretin

120-05-8

Aurones