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SULFURETIN

Product Name
SULFURETIN
CAS No.
120-05-8
Chemical Name
SULFURETIN
Synonyms
SULFURETIN;SULPHURETIN;SULFURETIN hplc;SULFURETIN WITH HPLC;3',4',6-TRIHYDROXYAURONE;6,3',4'-TRIHYDROXYAURONE;3',4',6-Trihydroxybenzalcoumaranone;2-(3,4-dihydroxybenzylidene)-6-hydroxy-2H-benzofuran-3-one;2-(3,4-Dihydroxybenzylidene)-6-hydroxy-3(2H)-benzofuranone;(Z)-2-(3,4-Dihydroxybenzylidene)-6-hydroxybenzofuran-3(2H)-one
CBNumber
CB5774890
Molecular Formula
C15H10O5
Formula Weight
270.24
MOL File
120-05-8.mol
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SULFURETIN Property

Melting point:
295°C
storage temp. 
2-8°C
solubility 
Acetone: Soluble
Chloroform: Soluble
Dichloromethane: Soluble
DMSO: SolubleEthyl Acetate: Soluble
form 
Solid
color 
Yellow to orange
LogP
1.980 (est)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3002
Product name
Sulfuretin
Purity
≥98% (HPLC)
Packaging
5MG
Price
$151.05
Updated
2025/07/31
Biosynth Carbosynth
Product number
FS137768
Product name
Sulfuretin
Packaging
1mg
Price
$225
Updated
2021/12/16
AK Scientific
Product number
9995AJ
Product name
Sulfurein
Packaging
2mg
Price
$320
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS137768
Product name
Sulfuretin
Packaging
2mg
Price
$350
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS137768
Product name
Sulfuretin
Packaging
5mg
Price
$550
Updated
2021/12/16
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SULFURETIN Chemical Properties,Usage,Production

Uses

Sulfuretin inhibits the inflammatory response by suppressing the NF-κB pathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis[1]. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC50 of 13.64 μM[2].

Definition

ChEBI: Sulfuretin is a member of 1-benzofurans.

Biological Activity

Anti-adipogenic, antineoplastic activity, antioxidative stress, Anti-Inflammatory

in vivo

Sulfuretin inhibits the inflammatory responses by suppressing the NF-κB pathway in type 1 diabetes models. Sulfuretin (40 μg/kg; single intraperitoneal injection 2 h after the last OVA challenge) suppresses ovalbumin (OVA)-induced chemotaxis and airway inflammation[1].

Animal Model:Pathogen-free male BALB/c mice (7-8 weeks old)[1]
Dosage:40 μg/kg
Administration:A single intraperitoneal injection was administered 2 h after the last OVA challenge
Result:Suppressed OVA-induced chemotaxis and airway inflammation.

References

[1] Mi-Young Song, et al. Sulfuretin attenuates allergic airway inflammation in mice. Biochem Biophys Res Commun. 2010 Sep 10;400(1):83-8. DOI:10.1016/j.bbrc.2010.08.014
[2] Chen, H., et al. Isolation of sulfuretin and butin from Rhus verniciflua Stokes using medium-pressure liquid chromatography and their tyrosinase inhibitory effects. BioRes. 11(1), 759-771.
[3] SO YOUNG KANG  Myung J O  Ji Young Kang. Antiviral activities of flavonoids isolated from the bark of Rhus verniciflua stokes against fish pathogenic viruses In Vitro.[J]. Journal of Microbiology, 2012, 50 2: 293-300. DOI: 10.1007/s12275-012-2068-7

SULFURETIN Preparation Products And Raw materials

Raw materials

Preparation Products

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SULFURETIN Suppliers

China 77 France 1 Germany 3 Japan 2 United Kingdom 5 United States 7 USA 1 Global 96
Nacalai Tesque, Inc.
Tel
--
Fax
--
Email
info-tech@nacalai.co.jp
Country
Japan
ProdList
6046
Advantage
75
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80

120-05-8, SULFURETINRelated Search:

AKOS BBS-00006136 AKOS BBS-00006112 AKOS BBS-00006130 MARITIMEIN RENGASIN-4'-O-GLUCOSIDE AKOS BBS-00006134 AKOS BBS-00006157 AUREUSIDIN-4-METHYL ETHER SULFURETIN AURORA 20031 AUREUSIDIN(RG) RENGASIN-3'-O-GLUCOSIDE

  • SULFURETIN
  • 6,3',4'-TRIHYDROXYAURONE
  • 3',4',6-TRIHYDROXYAURONE
  • 2-(3,4-dihydroxybenzylidene)-6-hydroxy-2H-benzofuran-3-one
  • (Z)-2-[(3,4-dihydroxyphenyl)methylene]-6-hydroxy-2H-benzofuran-3-one
  • SULPHURETIN
  • SULFURETIN WITH HPLC
  • SULFURETIN hplc
  • (Z)-2-[(3,4-Dihydroxyphenyl)methylene]-6-hydroxy-3(2H)-benzofuranone
  • 2-[(Z)-(3,4-Dihydroxyphenyl)methylene]-6-hydroxybenzofuran-3(2H)-one
  • 2-(3,4-Dihydroxybenzylidene)-6-hydroxy-3(2H)-benzofuranone
  • 3',4',6-Trihydroxybenzalcoumaranone
  • 3(2H)-Benzofuranone, 2-[(3,4-dihydroxyphenyl)methylene]-6-hydroxy-, (2Z)-
  • inflammation,platelet,Allergic,Sulfuretin,Nuclear factor-kappaB,Airway,Inhibitor,aggregation,monophenolase,diphenolase,NF-κB,mutagenesis,oxidative,Nuclear factor-κB,stress,Asthma,inhibit
  • (Z)-2-(3,4-Dihydroxybenzylidene)-6-hydroxybenzofuran-3(2H)-one
  • (Z)-2-(3,4-Dihydroxybenzylidene)-6-hydroxybenzofuran-3(2H)-one , Sulfuretin
  • 120-05-8
  • Aurones