ChemicalBook > CAS DataBase List > (+)-5,6-O-Isopropylidene-L-ascorbic acid

(+)-5,6-O-Isopropylidene-L-ascorbic acid

Product Name: (+)-5,6-O-Isopropylidene-L-ascorbic acid
CAS No.: 15042-01-0
Chemical Name: (+)-5,6-O-Isopropylidene-L-ascorbic acid
Synonyms: 5,6-ISOPROPYLIDENE-L-ASCORBIC ACID;5,6-O-ISOPROPYLIDENE-L-ASCORBIC ACID;(R)-5-((S)-2,2-Dimethyl-1,3-dioxolan-4-yl)-3,4-dihydroxyfuran-2(5H)-one;Iasa;NSC 252042;(+)-5,6-O-Isopropyli;L-Ascorbicacidacetonide;ASCORBIC ACID ACETONIDE;Isopropylidene ascorbic acid;5,5-ISOPROPYLIDENE-L-ASCORBIC ACID
CBNumber: CB5783467
Molecular Formula: C9H12O6
Formula Weight: 216.19
MOL File: 15042-01-0.mol

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(+)-5,6-O-Isopropylidene-L-ascorbic acid Property

Melting point:: 217 °C (dec.)
Boiling point:: 395.2±42.0 °C(Predicted)
alpha: 10.5 º (c=5%, MeOH)
Density: 1.518±0.06 g/cm3(Predicted)
refractive index: 10 ° (C=5, MeOH)
storage temp.: 2-8°C
solubility: Acetone, DMSO, Ethanol, Methanol
form: Solid
pka: 3.99±0.10(Predicted)
color: Off-White
optical activity: [α]19/D +25.3°, c = 1 in H2O
BRN: 86893
InChI: InChI=1S/C9H12O6/c1-9(2)13-3-4(15-9)7-5(10)6(11)8(12)14-7/h4,7,10-11H,3H2,1-2H3/t4-,7+/m0/s1
InChIKey: POXUQBFHDHCZAD-MHTLYPKNSA-N
SMILES: OC1=C(O)C(=O)O[C@@H]1[C@@H]1COC(O1)(C)C
CAS DataBase Reference: 15042-01-0(CAS DataBase Reference)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 10-21
HS Code: 2932990090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 301361
Product name: 5,6-Isopropylidene-L-ascorbic acid
Purity: 98%
Packaging: 5g
Price: $53.62
Updated: 2025/07/31

TCI Chemical

Product number: I0507
Product name: (+)-5,6-O-Isopropylidene-L-ascorbic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $145
Updated: 2025/07/31

TCI Chemical

Product number: I0507
Product name: (+)-5,6-O-Isopropylidene-L-ascorbic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $577
Updated: 2025/07/31

TRC

Product number: A787000
Product name: AscorbicAcidAcetonide
Packaging: 5g
Price: $60
Updated: 2021/12/16

Usbiological

Product number: A3774-90
Product name: Ascorbic Acid Acetonide
Packaging: 10g
Price: $355
Updated: 2021/12/16

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(+)-5,6-O-Isopropylidene-L-ascorbic acid Chemical Properties,Usage,Production

Chemical Properties

White Powder

Uses

5,6-O-Isopropylidene-L-ascorbic acid (L-Ascorbic acid 5,6-acetonide) is an organic compound. 5,6-O-Isopropylidene-L-ascorbic acid is a derivative of L-Ascorbic acid (vitamin C). Ascorbic acid has antioxidant properties.

Synthesis

50-81-7

15042-01-0

General procedure for the synthesis of 5,6-O-isopropylidene-L-ascorbic acid from vitamin C: Vitamin C (1.76 g, 10 mmol) and acetone (9 mL) were added to a reaction flask fitted with a magnetic stirrer and stirred until dissolved. Subsequently, phosphoryl chloride (0.5 mL) was added slowly and dropwise to the above solution. The reaction mixture was stirred continuously for 4 hours at room temperature. After completion of the reaction, the mixture was filtered, and the filter cake was washed with cold acetone-water (volume ratio adjusted according to the actual situation), and finally dried under vacuum to obtain the target compound 5,6-O-isopropylidene-L-ascorbic acid (1.92 g, 89% yield) as a colorless granular solid. The product was detected by IR (KBr press method) and the main absorption peaks were: νmax 3242.6, 2993.3, 2907.6, 2741.6, 1755.5, 1665.4 cm-1. 1H NMR (600 MHz, CD3COCD3) data: δ 4.71-4.73 (m, 1H, C4-H), 4.37-4.39 ( m, 1H, C5-H), 4.16-4.21 (m, 1H, C6-H), 3.99-4.03 (m, 1H, C6-H), 1.29 (s, 6H, Me).

References

[1] Pappenberger G, et al. Industrial production of L-ascorbic Acid (vitamin C) and D-isoascorbic acid. Adv Biochem Eng Biotechnol. 2014;143:143-88. DOI:10.1007/10_2013_243

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Raw materials

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View Lastest Price from (+)-5,6-O-Isopropylidene-L-ascorbic acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: (+)-5,6-O-Isopropylidene-L-ascorbic acid 15042-01-0
Price: US $0.00/G
Min. Order: 10G
Purity: 98%min
Supply Ability: 30kg/month
Release date: 2023-02-14

Zhuozhou Wenxi import and Export Co., Ltd

Product: (+)-5,6-O-Isopropylidene-L-ascorbic acid 15042-01-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: (+)-5,6-O-Isopropylidene-L-ascorbic acid 15042-01-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000KGS
Release date: 2020-01-02

15042-01-0, (+)-5,6-O-Isopropylidene-L-ascorbic acidRelated Search:

2,2-Dimethyl-1,3-dioxolane-4-methanol Sodium ascorbate Calcium ascorbate dihydrate ISOPROPYLMAGNESIUM CHLORIDE Sodium erythorbate Ascorbic Acid Ascoric Acid 2-ETHOXYETHYL ACRYLATE 1-ETHOXY-2-PROPYL ACETATE 2(5H)-Furanone 2-METHYL-1,3-DIOXOLANE (2-ISOPROPOXYETHYL) ACETATE 2,4-DIMETHYL, 1,3-DIOXALONE 2-Hydroxyethyl acrylate DL-ascorbic acid (S)-(-)HYDROXYMETHYL-3(2H)-FURANONE 4-Hydroxy-2(5H)-furanone (2-Propenyloxy)propanol

(+)-5,6-O-Isopropyli

NSC 252042

5,6-O-ISOPROPYLIDENE-L-ASCORBIC ACID

5,6-ISOPROPYLIDENE-L-ASCORBIC ACID

5,5-ISOPROPYLIDENE-L-ASCORBIC ACID

(R)-5-((S)-2,2-Dimethyl-1,3-dioxolan-4-yl)-3,4-dihydroxyfuran-2(5H)-one

5,6-Isopropylidene-L-ascorbic acid 98%

ASCORBIC ACID ACETONIDE

5,6-0,0-ISOPROPYLIDENE-L-ASCORBIC ACID

L-Ascorbicacidacetonide

L-Ascorbic acid, 5,6-O-(1-methylethylidene)-

(+)-5,6-O-ISOPROPYLIDENE-L-ASCORBIC ACID 99+%

5-O,6-O-Isopropylidene-L-ascorbic acid

Iasa

Isopropylidene ascorbic acid

5,6-Isopropylidene-L-ascorbic acid,(+)-5,6-O-Isopropylidene-L-ascorbic acid

5,6-isopropyridene-L-ascorbic acid

2-(2,2-dimethyl-1,3-dioxolan-4-yl)-4,5-dihydroxy-3-furanone

(+)-5,6-O-Isopropylidene-L-ascorbicAcid&gt

(+)-5,6-O-Isopropylidene-L-ascorbic acid

(2R)-2-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-3,4-dihydroxy-2H-furan-5-one

5,6-Isopropylidene-<sc>L</sc>-ascorbic acid

15042-01-0

15042-01-07

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