ChemicalBook > CAS DataBase List > 2H-1-BENZOPYRAN-2-CARBOXYLIC ACID, 6-CHLORO-3,4-DIHYDRO-

2H-1-BENZOPYRAN-2-CARBOXYLIC ACID, 6-CHLORO-3,4-DIHYDRO-

Product Name
2H-1-BENZOPYRAN-2-CARBOXYLIC ACID, 6-CHLORO-3,4-DIHYDRO-
CAS No.
40026-24-2
Chemical Name
2H-1-BENZOPYRAN-2-CARBOXYLIC ACID, 6-CHLORO-3,4-DIHYDRO-
Synonyms
6-Chlorochroman-2-carboxylic acid;6-chlorochromane-2-carboxylic acid;2H-1-BENZOPYRAN-2-CARBOXYLIC ACID, 6-CHLORO-3,4-DIHYDRO-;(+/-)-6-chloro-2,3-dihydro-4H-1-benzopyran-2-carboxylic acid
CBNumber
CB5787728
Molecular Formula
C10H9ClO3
Formula Weight
212.63
MOL File
40026-24-2.mol
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2H-1-BENZOPYRAN-2-CARBOXYLIC ACID, 6-CHLORO-3,4-DIHYDRO- Property

Boiling point:
394.7±42.0 °C(Predicted)
Density 
1.403±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
3.01±0.20(Predicted)
Appearance
White to light yellow Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
8470DA
Product name
6-Chlorochroman-2-carboxylicacid
Packaging
100mg
Price
$234
Updated
2021/12/16
AK Scientific
Product number
8470DA
Product name
6-Chlorochroman-2-carboxylicacid
Packaging
250mg
Price
$402
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0350995
Product name
6-CHLORO-3,4-DIHYDRO-2H-1-BENZOPYRAN-2-CARBOXYLIC ACID
Purity
95.00%
Packaging
5MG
Price
$503.23
Updated
2021/12/16
Acrotein
Product number
H-3794
Product name
6-Chlorochroman-2-carboxylicacid
Purity
97%
Packaging
0.25g
Price
$293.33
Updated
2021/12/16
Ambeed
Product number
A221855
Product name
6-Chlorochroman-2-carboxylicacid
Purity
97%
Packaging
100mg
Price
$111
Updated
2021/12/16
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2H-1-BENZOPYRAN-2-CARBOXYLIC ACID, 6-CHLORO-3,4-DIHYDRO- Chemical Properties,Usage,Production

Synthesis

52011-76-4

40026-24-2

c) Synthesis of (R,S)-6-chloro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid (9c): triethylsilane (2.4 mL, 12.5 mmol) was added slowly and dropwise to a suspension of trifluoroacetic acid (5 mL) of compound 9b (1.13 g, 5 mmol) under stirring. The reaction mixture was stirred continuously at 55°C for three days. Upon completion of the reaction, it was cooled to 25°C and the excess triethylsilane and solvent were removed by distillation under reduced pressure. The residue was dissolved in 1N sodium hydroxide solution and the resulting aqueous solution was washed with ether. Subsequently, the aqueous solution was acidified to pH ~1 with 6N hydrochloric acid and extracted with ethyl acetate. The organic extracts were combined, washed sequentially with water and saturated brine, and dried with anhydrous sodium sulfate. After filtration, the organic phase was concentrated under reduced pressure and finally dried under vacuum to give 0.95 g (90% yield) of the title compound 6-chloro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid.1H NMR (300 MHz, DMSO-d6) δ 13.08 (br s, 1H), 7.15 (m, 2H), 6.86 (d, 1H), 4.83 (t , 1H), 2.82 (m, 1H), 2.76 (m, 1H), 2.11 (m, 2H).

References

[1] Tetrahedron: Asymmetry, 1995, vol. 6, # 4, p. 1001 - 1012
[2] Patent: US2005/54630, 2005, A1. Location in patent: Page/Page column 36

2H-1-BENZOPYRAN-2-CARBOXYLIC ACID, 6-CHLORO-3,4-DIHYDRO- Preparation Products And Raw materials

Raw materials

Preparation Products

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2H-1-BENZOPYRAN-2-CARBOXYLIC ACID, 6-CHLORO-3,4-DIHYDRO- Suppliers

China 22 India 1 United States 3 Global 26
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
Chemgenx, LLC
Tel
--
Fax
--
Country
United States
ProdList
852
Advantage
60
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View Lastest Price from 2H-1-BENZOPYRAN-2-CARBOXYLIC ACID, 6-CHLORO-3,4-DIHYDRO- manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
6-Chlorochroman-2-carboxylic acid 40026-24-2
Price
US $1.00-100.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
300KG
Release date
2024-08-16

40026-24-2, 2H-1-BENZOPYRAN-2-CARBOXYLIC ACID, 6-CHLORO-3,4-DIHYDRO-Related Search:

MECOPROP 2H-1-BENZOPYRAN-2-CARBOXYLIC ACID, 6-CHLORO-3,4-DIHYDRO- 2-(4-chlorophenoxy)butyric acid

  • 6-Chlorochroman-2-carboxylic acid
  • 2H-1-BENZOPYRAN-2-CARBOXYLIC ACID, 6-CHLORO-3,4-DIHYDRO-
  • (+/-)-6-chloro-2,3-dihydro-4H-1-benzopyran-2-carboxylic acid
  • 6-chlorochromane-2-carboxylic acid
  • 40026-24-2