Azido-PEG12-NHS ester

Product Name: Azido-PEG12-NHS ester
CAS No.: 2363756-50-5
Chemical Name: Azido-PEG12-NHS ester
Synonyms: N3-PEG12-CH2CH2COONHS;Azido-PEG12-NHS eater;Azido PEG12 NHS ester,Azido-PEG-12-NHS ester,PROTAC Linkers,Inhibitor,AzidoPEG12NHS ester,inhibit
CBNumber: CB58054664
Molecular Formula: C31H56N4O16
Formula Weight: 740.8
MOL File: 2363756-50-5.mol

More

Less

Azido-PEG12-NHS ester Property

storage temp.: -20°C, sealed storage, away from moisture
solubility: Soluble in DMSO, DCM, DMF
form: Solid-Liquid Mixture
color: White to off-white

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

Azido-PEG12-NHS ester Chemical Properties,Usage,Production

Description

Azido-PEG12-NHS ester is a aqueous soluble crosslinker containing an azide group and an NHS ester. Ne azide can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Uses

Azido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG12-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azido-PEG12-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Azido-PEG12-NHS ester Suppliers

China 23 United States 2 Global 25

Chengdu Pukang Biotechnology Co., Ltd

Tel: +86-028-82550498 +86-19102685862
Fax: 086-28-82550468
Email: sales@pu-kang.com
Country: China
ProdList: 497
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 55000
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-80514535 19917294565
Email: et@chemextension.com
Country: China
ProdList: 5061
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Shanghai Easy CDMO Co.,Ltd

Tel: 021-61734564 13854185395;
Email: info@easycdmo.com
Country: China
ProdList: 10024
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
Advantage: 58

Xinyanpomei

Tel: 15850660754
Email: 15850660754@163.com
Country: China
ProdList: 847
Advantage: 58

Shandong fen Boyu Biotechnology Co.,LTD

Tel: 13356310019 13356310019;
Email: boyu2024@163.com
Country: China
ProdList: 3247
Advantage: 58

Chengdu Hanwei Biotechnology Co., Ltd

Tel: 17360178904 18217049878
Email: zengzongwen@pegtide.com
Country: China
ProdList: 1222
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: 400-6206333 13167063860
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 48457
Advantage: 58

Changsha Morning Shine Co., Ltd.

Tel: 189-75832125 13397510867
Email: BD@csmspharm.com
Country: China
ProdList: 399
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: 18143011203
Email: ET-market@chemextension.com
Country: China
ProdList: 32050
Advantage: 58

Shanghai Yanfen Biochemical Technology Co.,LTD

Tel: 17721070236 15002190549;
Email: yanfen2023@126.com
Country: China
ProdList: 1837
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd

Tel: 025-58851090 17714375163
Email: 2881759498@qq.com
Country: China
ProdList: 13011
Advantage: 58

Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6710
Advantage: 58

Changsha Morning Shine Co., Ltd.

Tel: +8613751227286
Email: chenkaijie@csmspharm.com
Country: China
ProdList: 300
Advantage: 58

Xian confluore Biological Technology Co., Ltd.

Tel: +86-15680926068
Email: 1924344760@confluore.cn
Country: China
ProdList: 2997
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: +undefined18143011203
Email: info@chemextension.com
Country: China
ProdList: 42056
Advantage: 58

Absin Bioscience Inc.

Tel: --
Fax: --
Email: chenjw@absin.cn
Country: CHINA
ProdList: 6208
Advantage: 58

Proteintech China

Tel: --
Fax: --
Email: Proteintech-CN@ptglab.com
Country: CHINA
ProdList: 6290
Advantage: 58

More

Less

View Lastest Price from Azido-PEG12-NHS ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: azido-PEG12-NHS ester 2363756-50-5
Price: US $0.00/g
Min. Order: 1g
Purity: >95.00%
Supply Ability: 1g
Release date: 2024-03-23

2363756-50-5, Azido-PEG12-NHS esterRelated Search:

N3-PEG12-N3 Azido-PEG12-Br Azide-PEG12-Tos N3-PEG12-OH N3-PEG12-Hydrazide N3-PEG12-CH2CH2COOH Azido-PEG12-NHBoc Azido-PEG12-Amine Azido-PEG12-t-butyl ester

Azido PEG12 NHS ester,Azido-PEG-12-NHS ester,PROTAC Linkers,Inhibitor,AzidoPEG12NHS ester,inhibit

Azido-PEG12-NHS eater

N3-PEG12-CH2CH2COONHS

2363756-50-5