ChemicalBook > CAS DataBase List > Azide-PEG12-Tos

Azide-PEG12-Tos

Product Name
Azide-PEG12-Tos
CAS No.
1821464-56-5
Chemical Name
Azide-PEG12-Tos
Synonyms
N3-PEG12-Tos;Azide-PEG12-Tos;Azido-PEG12-Tos;Azide PEG12 Tos,AzidePEG12Tos,Inhibitor,Azide-PEG-12-Tos,PROTAC Linkers,inhibit;35-azido-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontyl 4-methylbenzenesulfonate;N3-PEG12-Tos/3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontan-1-ol, 35-azido-, 1-(4-methylbenzenesulfonate);2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
CBNumber
CB53162854
Molecular Formula
C31H55N3O14S
Formula Weight
725.85
MOL File
1821464-56-5.mol
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Azide-PEG12-Tos Property

solubility 
Soluble in DMSO, DCM, DMF
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23149
Product name
Azide-PEG12-Tos
Purity
98%
Packaging
250mg
Price
$430
Updated
2021/12/16
Activate Scientific
Product number
AS107799
Product name
N3-PEG12-Tos
Purity
97%
Packaging
1g
Price
$1126
Updated
2021/12/16
Acrotein
Product number
B-1430
Product name
N3-PEG12-Tos
Purity
97%
Packaging
0.25g
Price
$366.67
Updated
2021/12/16
Acrotein
Product number
B-1430
Product name
N3-PEG12-Tos
Purity
97%
Packaging
0.5g
Price
$550
Updated
2021/12/16
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Azide-PEG12-Tos Chemical Properties,Usage,Production

Description

Azide-PEG12-Tos is a monodisperse PEG reagent containing an azide group and a tosyl group. Long PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The tosyl group is a good leaving group for nucleophilic reactions.

Uses

Azide-PEG12-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG12-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azide-PEG12-Tos Preparation Products And Raw materials

Raw materials

Preparation Products

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Azide-PEG12-Tos Suppliers

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-80534353 19917294565
Email
et@chemextension.com
Country
China
ProdList
3828
Advantage
55
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28772
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
Alpha Biopharmaceuticals Co., Ltd
Tel
0411-39042497
Fax
0411-39042693
Email
sales@alphabiopharm.com
Country
China
ProdList
1951
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
Advantage
58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19908
Advantage
58
Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
Tel
13892832556
Email
2440688701@qq.com
Country
China
ProdList
1995
Advantage
58
Xiamen Sinopeg Biotech Co., Ltd.
Tel
400-9189898 17359873007
Email
sales@sinopeg.com
Country
China
ProdList
1000
Advantage
58
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View Lastest Price from Azide-PEG12-Tos manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
N3-PEG12-Tos 1821464-56-5
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2026-02-04
Xian confluore Biological Technology Co., Ltd.
Product
Azido-PEG12-Tos 1821464-56-5
Price
US $0.00/g
Min. Order
1g
Purity
>95.00%
Supply Ability
1g
Release date
2024-03-23

1821464-56-5, Azide-PEG12-TosRelated Search:


  • Azide-PEG12-Tos
  • N3-PEG12-Tos
  • 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
  • Azido-PEG12-Tos
  • Azide PEG12 Tos,AzidePEG12Tos,Inhibitor,Azide-PEG-12-Tos,PROTAC Linkers,inhibit
  • N3-PEG12-Tos/3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontan-1-ol, 35-azido-, 1-(4-methylbenzenesulfonate)
  • 35-azido-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontyl 4-methylbenzenesulfonate
  • 1821464-56-5
  • C31H55N3O14S