ChemicalBook > CAS DataBase List > Boc-C1-PEG3-C4-OBn
Boc-C1-PEG3-C4-OBn
- Product Name
- Boc-C1-PEG3-C4-OBn
- CAS No.
- 2381196-81-0
- Chemical Name
- Boc-C1-PEG3-C4-OBn
- Synonyms
- Boc-C1-PEG3-C4-OBn;tert-butyl 2-[2-[2-(6-benzyloxyhexoxy)ethoxy]ethoxy]acetate;3,6,9,16-Tetraoxaheptadecanoic acid, 17-phenyl-, 1,1-dimethylethyl ester
- CBNumber
- CB58054684
- Molecular Formula
- C23H38O6
- Formula Weight
- 410.54
- MOL File
- 2381196-81-0.mol
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Boc-C1-PEG3-C4-OBn Property
- Boiling point:
- 486.9±40.0 °C(Predicted)
- Density
- 1.029±0.06 g/cm3(Predicted)
- solubility
- Soluble in DMSO
- form
- Liquid
- color
- Light yellow to yellow
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Boc-C1-PEG3-C4-OBn Chemical Properties,Usage,Production
Biological Activity
Boc-C1-PEG3-C4-OBn (PROTAC Linker 15) is a PROTAC linker, which refers to the PEG composition. Boc-C1-PEG3-C4-OBn can be used in the synthesis of a series of PROTACs, such as PROTAC SGK3 degrader-1. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTACDegrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.
Boc-C1-PEG3-C4-OBn Preparation Products And Raw materials
Raw materials
Preparation Products
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Boc-C1-PEG3-C4-OBn Suppliers
- Tel
- +1-781-999-5354 +1-00000000000
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- Country
- United States
- ProdList
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