Emapalumab

Product Name: Emapalumab
CAS No.: 1709815-23-5
Chemical Name: Emapalumab
Synonyms: NI-0501;Emapalumab;Emapalumab (anti-IFNγ);Research Grade Emapalumab;Research Grade Emapalumab(DHB95401)
CBNumber: CB58081011
Formula Weight: 0
MOL File: Mol file

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Emapalumab Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Emapalumab Chemical Properties,Usage,Production

Uses

Emapalumab (NI-0501) is a human monoclonal IgG1 antibody that noncompetitively inhibits IFN-γ. Emapalumab binds with high affinity (Kd= 1.4 pM) to both free IFN-γ as well as IFN-γ bound to its receptor. Emapalumab can be used in research of hemophagocytic lymphohistiocytosis (HLH)[1].

References

[1] Vallurupalli M, et, al. Emapalumab for the treatment of relapsed/refractory hemophagocytic lymphohistiocytosis. Blood. 2019 Nov 21;134(21):1783-1786. DOI:10.1182/blood.2019002289

Emapalumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Emapalumab Suppliers

China 18 United States 2 Global 20

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Emapalumab

Research Grade Emapalumab(DHB95401)

Emapalumab (anti-IFNγ)

NI-0501

Research Grade Emapalumab

1709815-23-5