ChemicalBook > CAS DataBase List > Relatlimab
Relatlimab
- Product Name
- Relatlimab
- CAS No.
- 1673516-98-7
- Chemical Name
- Relatlimab
- Synonyms
- ONO-4482;BMS986016;BMS-986016;Relatlimab;Relatlimab (DHD30403);Relatlimab (anti-LAG-3);Research Grade Relatlimab;Relatlimab (anti-LAG-3/CD223);Research Grade Relatlimab(DHD30403)
- CBNumber
- CB58081066
- Formula Weight
- 0
- MOL File
- Mol file
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Relatlimab Property
- form
- Liquid
- color
- Colorless to light yellow
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Relatlimab Chemical Properties,Usage,Production
Uses
Relatlimab (BMS-986016) is a human monoclonal antibody anti-LAG-3 antibody generated by immunization of transgenic mice bearing human immunoglobulin miniloci with recombinant LAG-3 protein. Relatlimab blocks LAG-3/MHC II interaction with an IC50 value of 0.67 nM and LAG-3/FGL1 interaction with an IC50 value of 0.019 nM. Relatlimab can be used in research of cancer[1].
References
[1] Thudium K, et, al. Preclinical Characterization of Relatlimab, a Human LAG-3-Blocking Antibody, Alone or in Combination with Nivolumab. Cancer Immunol Res. 2022 Aug 18:CIR-22-0057. DOI:10.1158/2326-6066.CIR-22-0057
Relatlimab Preparation Products And Raw materials
Raw materials
Preparation Products
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