3-(tert-Butyl)-6-(ethylthio)-1,3,5-triazine-2,4(1H,3H)-dione

Product Name: 3-(tert-Butyl)-6-(ethylthio)-1,3,5-triazine-2,4(1H,3H)-dione
CAS No.: 1360105-53-8
Chemical Name: 3-(tert-Butyl)-6-(ethylthio)-1,3,5-triazine-2,4(1H,3H)-dione
Synonyms: 3-tert-butyl-6-(ethylthio)-1,3,5-triazine-2,4(1H,3H)-dione;3-(1,1-DIMETHYLETHYL)-6-(ETHYLTHIO)-1,3,5-TRIAZINE-2,4(1H,3H)-DIONE;6-(ethylthio)-3-t-butyl-1,3,5-triazine-2,4(1H,3H)-dion;3-TERT-BUTYL-6-ETHYLSULFANYL-1H-1,3,5-TRIAZINE-2,4-DIONE;1,3,5-Triazine-2,4(1H,3H)-dione, 3-(1,1-dimethylethyl)-6;3-Sanchoyl-6-(sulfide)-1,3,5-Sanji - 2,4 (1H, 3H) - Niket;1,3,5-Triazine-2,4(1H,3H)-dione, 3-(1,1-dimethylethyl)-6-(ethylthio)-
CBNumber: CB58093139
Molecular Formula: C9H15N3O2S
Formula Weight: 229.3
MOL File: 1360105-53-8.mol

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3-(tert-Butyl)-6-(ethylthio)-1,3,5-triazine-2,4(1H,3H)-dione Property

Density: 1.27±0.1 g/cm3(Predicted)
pka: 5.15±0.70(Predicted)
InChI: InChI=1S/C9H15N3O2S/c1-5-15-6-10-7(13)12(8(14)11-6)9(2,3)4/h5H2,1-4H3,(H,10,11,13,14)
InChIKey: BDGLMLJBANMNCP-UHFFFAOYSA-N
SMILES: N1C(SCC)=NC(=O)N(C(C)(C)C)C1=O

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Hazard and Precautionary Statements (GHS)

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3-(tert-Butyl)-6-(ethylthio)-1,3,5-triazine-2,4(1H,3H)-dione Chemical Properties,Usage,Production

Uses

3-(tert-Butyl)-6-(ethylthio)-1,3,5-triazine-2,4(1H,3H)-dione is used as Ensitrelvir intermediates.

Acquired resistance

T-Butyl isocyanate (1.2 mL, 10.5 mmol) and DBU (1.9 mL, 12.8 mmol) were added to mixture of S-ethylthiourea hydrobromate (1.85 g, 10 mmol) and DMF (9.3 mL) under ice-cooling, and the resulting mixture was stirred for 6 hours. 1,1′-Carbonyldiimidazole (1.95 g, 12 mmol) and DBU (1.9 mL, 12.8 mmol) were added to the reaction mixture under ice-cooling, and the mixture was stirred for 2 hours. 2 mol/L Hydrochloric acid (80 mL) was added to the reaction mixture under ice-cooling over 50 minutes, and the generated powder was collected by filtration. The powder was dissolved in ethyl acetate, dried over anhydrous magnesium sulfate, and concentrated in vacuo to give 3-(tert-Butyl)-6-(ethylthio)-1,3,5-triazine-2,4(1H,3H)-dione (1.15 g, yield: 50%) as pale brown powder.

Synthesis

T-Butyl isocyanate (1.2 mL, 10.5 mmol) and DBU (1.9 mL, 12.8 mmol) were added to mixture of S-ethylthiourea hydrobromate (1.85 g, 10 mmol) and DMF (9.3 mL) under ice-cooling, and the resulting mixture was stirred for 6 hours. 1,1′-Carbonyldiimidazole (1.95 g, 12 mmol) and DBU (1.9 mL, 12.8 mmol) were added to the reaction mixture under ice-cooling, and the mixture was stirred for 2 hours. 2 mol/L Hydrochloric acid (80 mL) was added to the reaction mixture under ice-cooling over 50 minutes, and the generated powder was collected by filtration. The powder was dissolved in ethyl acetate, dried over anhydrous magnesium sulfate, and concentrated in vacuo to give 3-(tert-Butyl)-6-(ethylthio)-1,3,5-triazine-2,4(1H,3H)-dione (1.15 g, yield: 50%) as pale brown powder.

3-(tert-Butyl)-6-(ethylthio)-1,3,5-triazine-2,4(1H,3H)-dione Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(tert-Butyl)-6-(ethylthio)-1,3,5-triazine-2,4(1H,3H)-dione Suppliers

China 167 India 2 Global 169

Jinan XuanDe Chemical Co., Ltd.

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Energy Chemical

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View Lastest Price from 3-(tert-Butyl)-6-(ethylthio)-1,3,5-triazine-2,4(1H,3H)-dione manufacturers

Wuhan Cell Pharmaceutical Co., Ltd

Product: 1,3,5-Triazine-2,4(1H,3H)-dione, 3-(1,1-dimethylethyl)-6-(ethylthio)- 1360105-53-8
Price: US $9.90-9.90/g
Min. Order: 1g
Purity: 99%
Supply Ability: 10kg
Release date: 2023-03-30

Wuhan Cell Pharmaceutical Co., Ltd

Product: 1,3,5-Triazine-2,4(1H,3H)-dione, 3-(1,1-dimethylethyl)-6-(ethylthio)- 1360105-53-8
Price: US $9.90-9.90/g
Min. Order: 1g
Purity: 99%
Supply Ability: 10kg
Release date: 2023-03-30

Anhui Yiao New Material Technology Co., Ltd

Product: 1,3,5-Triazine-2,4(1H,3H)-dione, 3-(1,1-dimethylethyl)-6-(ethylthio)- 1360105-53-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1 ton
Release date: 2023-11-02

1360105-53-8, 3-(tert-Butyl)-6-(ethylthio)-1,3,5-triazine-2,4(1H,3H)-dioneRelated Search:

1,3,5-Triazine-2,4(1H,3H)-dione, 3-(1,1-dimethylethyl)-6-(ethylthio)-

3-tert-butyl-6-(ethylthio)-1,3,5-triazine-2,4(1H,3H)-dione

3-(1,1-DIMETHYLETHYL)-6-(ETHYLTHIO)-1,3,5-TRIAZINE-2,4(1H,3H)-DIONE

3-Sanchoyl-6-(sulfide)-1,3,5-Sanji - 2,4 (1H, 3H) - Niket

1,3,5-Triazine-2,4(1H,3H)-dione, 3-(1,1-dimethylethyl)-6

6-(ethylthio)-3-t-butyl-1,3,5-triazine-2,4(1H,3H)-dion

3-TERT-BUTYL-6-ETHYLSULFANYL-1H-1,3,5-TRIAZINE-2,4-DIONE

1360105-53-8

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S-217622

1360105-53-8