ChemicalBook > CAS DataBase List > Fomc-Gly-Gly-Phe-Gly-OH

Fomc-Gly-Gly-Phe-Gly-OH

Product Name
Fomc-Gly-Gly-Phe-Gly-OH
CAS No.
1817857-75-2
Chemical Name
Fomc-Gly-Gly-Phe-Gly-OH
Synonyms
Fmoc-GGFG;Fmoc-GGFG-OH;Fomc-Gly-Gly-Phe-Gly;Fomc-Gly-Gly-Phe-Gly-OH;(((9H-Fluoren-9-yl)methoxy)carbonyl)glycylglycyl-L-phenylalanylglycine;Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycylglycyl-L-phenylalanyl-;(S)-2-[2-[2-[2-(Fmoc-amino)acetamido]acetamido]-3-phenylpropanamido]acetic Acid
CBNumber
CB58110012
Molecular Formula
C30H30N4O7
Formula Weight
558.58
MOL File
1817857-75-2.mol
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Fomc-Gly-Gly-Phe-Gly-OH Property

Boiling point:
980.0±65.0 °C(Predicted)
Density 
1.329±0.06 g/cm3(Predicted)
pka
3.32±0.10(Predicted)
form 
Solid
color 
White to off-white
InChIKey
LCOCGQVZUSLQJD-VWLOTQADSA-N
SMILES
C(O)(=O)CNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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Fomc-Gly-Gly-Phe-Gly-OH Chemical Properties,Usage,Production

Uses

Fomc-Gly-Gly-Phe-Gly-OH, also known as FMOC-GGFG-OH or 2-[[(2S)-2-[[2-[[2-(9H-fluoren-9-ylmethoxycarbonylamino)acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]acetic acid, can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit

Definition

Fomc-gly-gly-ph-gly-OH contains several functional groups. The Fmoc group is a commonly used protective group in peptide synthesis and is often used to protect N-terminal amino groups. Gly-Gly-Phe-Gly is glycyl-glycyl-phenylalanyl-glycine (GGFG) peptide which can be linked to other groups (drug) through cysteine residues. This tetrapeptide linker is protease-cleavable.

Fomc-Gly-Gly-Phe-Gly-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Fomc-Gly-Gly-Phe-Gly-OH Suppliers

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1817857-75-2, Fomc-Gly-Gly-Phe-Gly-OHRelated Search:


  • Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycylglycyl-L-phenylalanyl-
  • (((9H-Fluoren-9-yl)methoxy)carbonyl)glycylglycyl-L-phenylalanylglycine
  • Fmoc-GGFG
  • Fmoc-GGFG-OH
  • (S)-2-[2-[2-[2-(Fmoc-amino)acetamido]acetamido]-3-phenylpropanamido]acetic Acid
  • Fomc-Gly-Gly-Phe-Gly
  • Fomc-Gly-Gly-Phe-Gly-OH
  • 1817857-75-2
  • C30H30N4O7