Fomc-Gly-Gly-Phe-Gly-OH
- Product Name
- Fomc-Gly-Gly-Phe-Gly-OH
- CAS No.
- 1817857-75-2
- Chemical Name
- Fomc-Gly-Gly-Phe-Gly-OH
- Synonyms
- Fmoc-GGFG;Fmoc-GGFG-OH;Fomc-Gly-Gly-Phe-Gly;Fomc-Gly-Gly-Phe-Gly-OH;(((9H-Fluoren-9-yl)methoxy)carbonyl)glycylglycyl-L-phenylalanylglycine;Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycylglycyl-L-phenylalanyl-;(S)-2-[2-[2-[2-(Fmoc-amino)acetamido]acetamido]-3-phenylpropanamido]acetic Acid
- CBNumber
- CB58110012
- Molecular Formula
- C30H30N4O7
- Formula Weight
- 558.58
- MOL File
- 1817857-75-2.mol
Fomc-Gly-Gly-Phe-Gly-OH Property
- Boiling point:
- 980.0±65.0 °C(Predicted)
- Density
- 1.329±0.06 g/cm3(Predicted)
- pka
- 3.32±0.10(Predicted)
- form
- Solid
- color
- White to off-white
- InChIKey
- LCOCGQVZUSLQJD-VWLOTQADSA-N
- SMILES
- C(O)(=O)CNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Fomc-Gly-Gly-Phe-Gly-OH Chemical Properties,Usage,Production
Uses
Fomc-Gly-Gly-Phe-Gly-OH, also known as FMOC-GGFG-OH or 2-[[(2S)-2-[[2-[[2-(9H-fluoren-9-ylmethoxycarbonylamino)acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]acetic acid, can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit
Definition
Fomc-gly-gly-ph-gly-OH contains several functional groups. The Fmoc group is a commonly used protective group in peptide synthesis and is often used to protect N-terminal amino groups. Gly-Gly-Phe-Gly is glycyl-glycyl-phenylalanyl-glycine (GGFG) peptide which can be linked to other groups (drug) through cysteine residues. This tetrapeptide linker is protease-cleavable.
Fomc-Gly-Gly-Phe-Gly-OH Preparation Products And Raw materials
Raw materials
Preparation Products
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