6-TRIFLUOROMETHOXY-PYRIDIN-3-YLAMINE

Product Name: 6-TRIFLUOROMETHOXY-PYRIDIN-3-YLAMINE
CAS No.: 135900-33-3
Chemical Name: 6-TRIFLUOROMETHOXY-PYRIDIN-3-YLAMINE
Synonyms: 6-TRIFLUOROMETHOXY-PYRIDIN-3-Y;6-(Trifluoromethoxy)3-pyridinamine;6-(trifluoroMethoxy)pyridin-3-aMine;3-Amino-6-(trifluoromethoxy)pyridine;5-Amino-2-(trifluoromethoxy)pyridine;6-TRIFLUOROMETHOXY-PYRIDIN-3-YLAMINE;3-PyridinaMine, 6-(trifluoroMethoxy)-;3-Amino-6-(trifluoromethoxy)pyridine 95%;6-(trifluoromethoxy)pyridin-3-amine hydrochloride
CBNumber: CB5819533
Molecular Formula: C6H5F3N2O
Formula Weight: 178.11
MOL File: 135900-33-3.mol

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6-TRIFLUOROMETHOXY-PYRIDIN-3-YLAMINE Property

Melting point:: 31-33 °C(Solv: cyclohexane (110-82-7))
Boiling point:: 203.3±35.0 °C(Predicted)
Density: 1.421±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 1.72±0.10(Predicted)
Appearance: Colorless to light pink <31°C Solid,>33°C Liquid

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: T897680
Product name: 6-(Trifluoromethoxy)pyridin-3-amine
Packaging: 2.5mg
Price: $65
Updated: 2021/12/16

TRC

Product number: T897680
Product name: 6-(Trifluoromethoxy)pyridin-3-amine
Packaging: 5mg
Price: $90
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0353652
Product name: 6-TRIFLUOROMETHOXY-PYRIDIN-3-YLAMINE
Purity: 95.00%
Packaging: 5MG
Price: $495.83
Updated: 2021/12/16

Apolloscientific

Product number: PC53248
Product name: 3-Amino-6-(trifluoromethoxy)pyridine
Purity: 95%
Packaging: 250mg
Price: $700
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-3-AH
Product name: 6-(Trifluoromethoxy)pyridin-3-amine
Packaging: 250mg
Price: $1120
Updated: 2021/12/16

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6-TRIFLUOROMETHOXY-PYRIDIN-3-YLAMINE Chemical Properties,Usage,Production

Uses

6-(Trifluoromethoxy)pyridin-3-amine can be used to study synthesis of (Trifluoromethoxy)pyridines.

Synthesis

1221172-05-9

135900-33-3

General procedure for the synthesis of 6-(trifluoromethoxy)pyridin-3-amine from compound (CAS:1221172-05-9): compound 81 (2.00 g, 9.43 mmol, 1.0 eq.), 10% Pd/C (1.0 g), and ammonium formate (1.2 g, 18.9 mmol, 2.0 eq.) were dissolved in methanol (20 mL) and heated to 55 °C for 16 hours. After completion of the reaction, the mixture was cooled to room temperature, filtered through diatomaceous earth and the filtrate was concentrated to obtain the crude product. The crude product was partitioned between ethyl acetate (100 mL) and 4% NaOH aqueous solution (30 mL) to separate the organic layer. The organic layer was washed with saturated saline, dried over anhydrous sodium sulfate, filtered and concentrated to give the target product 82 (1.50 g, 8.38 mmol, 89.4% yield) as a yellow oil.

References

[1] Patent: WO2016/144792, 2016, A1. Location in patent: Paragraph 00537
[2] Patent: WO2010/40461, 2010, A1. Location in patent: Page/Page column 49
[3] European Journal of Organic Chemistry, 2010, # 31, p. 6043 - 6066

6-TRIFLUOROMETHOXY-PYRIDIN-3-YLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-TRIFLUOROMETHOXY-PYRIDIN-3-YLAMINE Suppliers

China 47 India 1 United Kingdom 1 United States 5 Global 54

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135900-33-3, 6-TRIFLUOROMETHOXY-PYRIDIN-3-YLAMINERelated Search:

6-TRIFLUOROMETHOXY-PYRIDIN-3-YLAMINE

6-(trifluoroMethoxy)pyridin-3-aMine

3-PyridinaMine, 6-(trifluoroMethoxy)-

3-Amino-6-(trifluoromethoxy)pyridine 95%

6-(trifluoromethoxy)pyridin-3-amine hydrochloride

6-(Trifluoromethoxy)3-pyridinamine

6-TRIFLUOROMETHOXY-PYRIDIN-3-Y

5-Amino-2-(trifluoromethoxy)pyridine

3-Amino-6-(trifluoromethoxy)pyridine

135900-33-3