ChemicalBook > CAS DataBase List > (6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE

(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE

Product Name
(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE
CAS No.
1227675-51-5
Chemical Name
(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE
Synonyms
SCH 39166 HYDROBROMIDE;(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE
CBNumber
CB5828599
Molecular Formula
C19H21BrClNO
Formula Weight
394.74
MOL File
Mol file
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(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE Property

storage temp. 
Desiccate at RT
solubility 
DMSO: Slightly Soluble; Methanol: Slightly Soluble; Water: Slightly Soluble
form 
A solid
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2591
Product name
SCH-39166 hydrobromide
Purity
≥98% (HPLC)
Packaging
5MG
Price
$123
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2591
Product name
SCH-39166 hydrobromide
Purity
≥98% (HPLC)
Packaging
25MG
Price
$495
Updated
2024/03/01
Cayman Chemical
Product number
25331
Product name
SCH 39166 (hydrobromide)
Purity
≥98%
Packaging
1mg
Price
$40
Updated
2024/03/01
Cayman Chemical
Product number
25331
Product name
SCH 39166 (hydrobromide)
Purity
≥98%
Packaging
5mg
Price
$158
Updated
2024/03/01
Cayman Chemical
Product number
25331
Product name
SCH 39166 (hydrobromide)
Purity
≥98%
Packaging
10mg
Price
$276
Updated
2024/03/01
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(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE Chemical Properties,Usage,Production

Description

SCH 39166 is a dopamine D1 receptor antagonist (Ki = 5 nM). It is selective for D1 over D2-4 receptors (Kis = 3,751, >1,000, and 5,934 nM, respectively), however, it also binds to D5 receptors (Ki = 4.4 nM). SCH 39166 inhibits food intake in a dose-dependent manner in rats (ED50 = 0.84 mg/kg). It reduces ethanol intake in Sardinian alcohol-preferring rats and sucrose intake in water-deprived and water-sated rats without affecting food or total fluid intake. SCH 39166 also suppresses cocaine-induced arrhythmias in anesthetized dogs.

Uses

SCH 39166 is a dopamine D1/D5 receptor antagonist used in the treatment of schizophrenia, cocaine addiction and obesity.

storage

Desiccate at RT

(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE Suppliers

China 8 United Kingdom 1 United States 4 USA 1 Global 14
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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86-21-50328109
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3bsc@sina.com
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China
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
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400-400-6206333 18521732826
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021-50323701
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market@aladdin-e.com
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China
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25003
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767
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Energy Chemical
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marketing1@energy-chemical.com
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MedBioPharmaceutical Technology Inc
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021-69568360 18916172912
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order@med-bio.cn
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LEAPCHEM CO., LTD.
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+86-852-30606658
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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1227675-51-5, (6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDERelated Search:


  • SCH 39166 HYDROBROMIDE
  • (6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE
  • 1227675-51-5
  • C19H20ClNOHBr
  • Dopamine receptor