ChemicalBook > CAS DataBase List > (6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE
(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE
- Product Name
- (6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE
- CAS No.
- 1227675-51-5
- Chemical Name
- (6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE
- Synonyms
- SCH 39166 HYDROBROMIDE;(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE
- CBNumber
- CB5828599
- Molecular Formula
- C19H21BrClNO
- Formula Weight
- 394.74
- MOL File
- Mol file
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(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE Property
- storage temp.
- Desiccate at RT
- solubility
- DMSO: Slightly Soluble; Methanol: Slightly Soluble; Water: Slightly Soluble
- form
- A solid
- Stability:
- Hygroscopic
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML2591
- Product name
- SCH-39166 hydrobromide
- Purity
- ≥98% (HPLC)
- Packaging
- 5MG
- Price
- $123
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- SML2591
- Product name
- SCH-39166 hydrobromide
- Purity
- ≥98% (HPLC)
- Packaging
- 25MG
- Price
- $495
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 25331
- Product name
- SCH 39166 (hydrobromide)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $40
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 25331
- Product name
- SCH 39166 (hydrobromide)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $158
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 25331
- Product name
- SCH 39166 (hydrobromide)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $276
- Updated
- 2024/03/01
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(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE Chemical Properties,Usage,Production
Description
SCH 39166 is a dopamine D1 receptor antagonist (Ki = 5 nM). It is selective for D1 over D2-4 receptors (Kis = 3,751, >1,000, and 5,934 nM, respectively), however, it also binds to D5 receptors (Ki = 4.4 nM). SCH 39166 inhibits food intake in a dose-dependent manner in rats (ED50 = 0.84 mg/kg). It reduces ethanol intake in Sardinian alcohol-preferring rats and sucrose intake in water-deprived and water-sated rats without affecting food or total fluid intake. SCH 39166 also suppresses cocaine-induced arrhythmias in anesthetized dogs.
Uses
SCH 39166 is a dopamine D1/D5 receptor antagonist used in the treatment of schizophrenia, cocaine addiction and obesity.
storage
Desiccate at RT
(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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