RS 504393

ChemicalBook > CAS DataBase List > RS 504393

Product Name: RS 504393
CAS No.: 300816-15-3
Chemical Name: RS 504393
Synonyms: RS 504393;RS-504393; RS504393;RS504393 >=98% (HPLC);6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spir...;CC chemokine receptor,RS504393,Inhibitor,RS 504393,inhibit,CCR,RS-504393;6-Methyl-1'-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidi;6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro-[benzo[d][1,3]oxazine-4,4'-piperidin];6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro-[benzo[d][1,3]oxazine-4,4'-piperidin]-2(;6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one;6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one
CBNumber: CB5837883
Molecular Formula: C25H27N3O3
Formula Weight: 417.5
MOL File: 300816-15-3.mol

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RS 504393 Property

Density: 1.28
storage temp.: 2-8°C
solubility: DMSO: soluble1mg/mL, clear (warmed)
form: powder
color: white to beige

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0711
Product name: RS504393
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $152
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0711
Product name: RS504393
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $633
Updated: 2024/03/01

Cayman Chemical

Product number: 17330
Product name: RS 504393
Purity: ≥98%
Packaging: 1mg
Price: $45
Updated: 2024/03/01

Cayman Chemical

Product number: 17330
Product name: RS 504393
Purity: ≥98%
Packaging: 5mg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 17330
Product name: RS 504393
Purity: ≥98%
Packaging: 10mg
Price: $198
Updated: 2024/03/01

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RS 504393 Chemical Properties,Usage,Production

Uses

RS 504393 is a small molecule antagonist at the CC chemokine receptor 2.

Uses

RS504393 has been used in mass spectrometry.

Definition

ChEBI: 6-methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-2-spiro[1H-3,1-benzoxazine-4,4'-piperidine]one is a member of 1,3-oxazoles.

Biological Activity

Extremely selective CCR2 chemokine receptor antagonist (IC 50 values are 98 nM and > 100 μ M for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Inhibits MCP-1 chemotaxis (IC 50 = 330 nM) and ischemia-reperfusion injury in kidneys.

Biochem/physiol Actions

RS504393 is a highly selective CCR2 chemokine receptor antagonist. RS504393 inhibits MCP-1 chemotaxis and ischemia-reperfusion injury in kidneys.

storage

Store at +4°C

RS 504393 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from RS 504393 manufacturers

Career Henan Chemical Co

Product: RS 504393 300816-15-3
Price: US $5.50/KG
Min. Order: 1IU
Purity: 98%min
Supply Ability: 1kg-100kg
Release date: 2020-01-10

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RS 504393

6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one

RS-504393; RS504393

RS504393 >=98% (HPLC)

6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spir...

CC chemokine receptor,RS504393,Inhibitor,RS 504393,inhibit,CCR,RS-504393

6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one

6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one

300816-15-3