ChemicalBook > CAS DataBase List > 4-(3-HYDROXY-PROPYL)-BENZONITRILE

4-(3-HYDROXY-PROPYL)-BENZONITRILE

Product Name
4-(3-HYDROXY-PROPYL)-BENZONITRILE
CAS No.
83101-12-6
Chemical Name
4-(3-HYDROXY-PROPYL)-BENZONITRILE
Synonyms
4-(3-HYDROXY-PROPYL)-BENZONITRILE;Benzonitrile, 4-(3-hydroxypropyl)-
CBNumber
CB5840948
Molecular Formula
C10H11NO
Formula Weight
161.2
MOL File
83101-12-6.mol
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4-(3-HYDROXY-PROPYL)-BENZONITRILE Property

storage temp. 
2-8°C
Appearance
Colorless to light yellow Liquid
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Safety

HS Code 
2926907090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A425510
Product name
4-(3-Hydroxypropyl)benzonitrile
Packaging
50mg
Price
$110
Updated
2021/12/16
TRC
Product number
A425510
Product name
4-(3-Hydroxypropyl)benzonitrile
Packaging
100mg
Price
$175
Updated
2021/12/16
AK Scientific
Product number
Z5162
Product name
4-(3-Hydroxypropyl)benzonitrile
Packaging
1g
Price
$386
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0138377
Product name
4-(3-HYDROXYPROPYL)BENZONITRILE
Purity
95.00%
Packaging
1G
Price
$918.06
Updated
2021/12/16
Alichem
Product number
83101126
Product name
4-(3-Hydroxypropyl)benzonitrile
Packaging
500mg
Price
$980
Updated
2021/12/16
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4-(3-HYDROXY-PROPYL)-BENZONITRILE Chemical Properties,Usage,Production

Synthesis

42287-94-5

83101-12-6

4) Synthesis of 3-(4-cyanophenyl)propanol Borane-tetrahydrofuran complex (1.0 M, 33.0 mL, 33.0 mmol, dissolved in tetrahydrofuran) was slowly added dropwise to a stirred tetrahydrofuran solution (50 mL) of 3-(4-cyanophenyl)propanoic acid (4.40 g, 25.1 mmol). The reaction mixture was stirred continuously for 14 hours at room temperature. Upon completion of the reaction, water (50 mL) and potassium carbonate (10.0 g, 72.4 mmol) were added to the mixture. Subsequently, the mixture was extracted with ethyl acetate, and the combined organic phases were washed with saturated brine, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure to afford 3-(4-cyanophenyl)propanol as a yellow oil (3.20 g, 79% yield). 1H-NMR (200 MHz, CDCl3) δ: 7.58 (2H, d, J = 8.2 Hz), 7.31 (2H, d, J = 8.2 Hz), 3.68 (2H, t, J = 6.2 Hz), 2.79 (2H, t, J = 7.8 Hz), 2.00-1.75 (2H, m). IR (pure): 3319, 2943, 2229, 1608, 1505, 1415, 1054, 854, 817 cm-1.

References

[1] Patent: US6235731, 2001, B1

4-(3-HYDROXY-PROPYL)-BENZONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(3-HYDROXY-PROPYL)-BENZONITRILE Suppliers

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