Alclometasone
- Product Name
- Alclometasone
- CAS No.
- 67452-97-5
- Chemical Name
- Alclometasone
- Synonyms
- Vaderm;Alclometasone;AlcloMethasone;ALCLOMETHASONE DIPROPIONATE;7α-Chloro-16α-methylprednisolone;7α-Chloro-16α-methyl Prednisolone;7α-Chloro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione;(7α,11β,16α)-7-Chloro-11,17,21-trihydroxy-16-Methylpregna-1,4-diene-3,20-dione;Pregna-1,4-diene-3,20-dione, 7-chloro-11,17,21-trihydroxy-16-methyl-, (7α,11β,16α)-
- CBNumber
- CB5875588
- Molecular Formula
- C22H29ClO5
- Formula Weight
- 408.919
- MOL File
- 67452-97-5.mol
Alclometasone Property
- Melting point:
- 176-179°
- alpha
- D26 +47.5° (c = 0.3 in DMF)
- Boiling point:
- 607.1±55.0 °C(Predicted)
- Density
- 1.34±0.1 g/cm3(Predicted)
- pka
- 12.30±0.70(Predicted)
N-Bromosuccinimide Price
- Product number
- C369475
- Product name
- 7α-Chloro-16α-methylPrednisolone
- Packaging
- 25mg
- Price
- $1980
- Updated
- 2021/12/16
- Product number
- API0005896
- Product name
- ALCLOMETASONE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $15303.75
- Updated
- 2021/12/16
Alclometasone Chemical Properties,Usage,Production
Uses
A metabolite of Alclometasone dipropionate (A514580); a synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive agent.
Uses
As a metabolite of Alclometasone dipropionate; Alclometasone can be used as a synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive agent.
Definition
ChEBI: A prednisolone compound having an alpha-chloro substituent at the 7-position and an alpha-methyl substituent at the 16-position.
brand name
Aclovate (GlaxoSmithKline).
in vivo
The prodrug of alclometasone is alclometasone dipropionate[2].Alclometasone dipropionate (subcutaneous injection; 1 % (w/v) arabic gum; 2 weeks) inhibits the activity of androgen-dependent cytochrome P450 and O-depropylation activity as a dose-dependent manner in male Slc-Wistar strain rats. However, it has no effects on hepatic drug metabolism in female rats or DS strain mice[2].
Alclometasone Preparation Products And Raw materials
Raw materials
Preparation Products
Alclometasone Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 15402
- Advantage
- 60
- Tel
- 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 9923
- Advantage
- 65
- Tel
- 86 512-62572107 62962707
- Fax
- 86 512-62922078
- Country
- China
- ProdList
- 800
- Advantage
- 58
- Tel
- sales@njromanme.com
- Country
- China
- ProdList
- 4529
- Advantage
- 58
- Tel
- 027-87466105 15377573527
- 2678564200@qq.com
- Country
- China
- ProdList
- 17987
- Advantage
- 58
- Tel
- 15971444841
- Fax
- 18327183813
- amber@biochempartner.com
- Country
- China
- ProdList
- 3061
- Advantage
- 58
- Tel
- +86-400-002-6226 +86-13028896684;
- sales@rrkchem.com
- Country
- China
- ProdList
- 57422
- Advantage
- 58
- Tel
- +8615255079626
- eric@witopchemical.com
- Country
- China
- ProdList
- 23541
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58