pimagedine

Product Name: pimagedine
CAS No.: 79-17-4
Chemical Name: pimagedine
Synonyms: pimagedine;Aids030897;Aids-030897;Aminate base;1-Aminoguanidine;N-Aminoguanidine;Monoaminoguanidine;Aminoguanidine (ag);Ribavirin Impurity S;Aminoguanidine mordant
CBNumber: CB5875700
Molecular Formula: CH6N4
Formula Weight: 74.09
MOL File: 79-17-4.mol

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pimagedine Property

Melting point:: 182-185 °C (decomp)
Boiling point:: 159.5±23.0 °C(Predicted)
Density: 1.72±0.1 g/cm3(Predicted)
refractive index: 1.6660 (estimate)
pka: 11.08±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: P445105
Product name: Pimagedinehydrochloride
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 18895
Product name: Pimagedine
Purity: 98%
Packaging: 5mg
Price: $950
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0000371
Product name: AMINOGUANIDINE
Purity: 95.00%
Packaging: 25G
Price: $1146.05
Updated: 2021/12/16

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pimagedine Chemical Properties,Usage,Production

Chemical Properties

Aminoguanidine is prepared from hydrazine and aqueous cyanamide solution. Processes based on the reduction of nitroguanidine have no industrial significance.

Chemical Properties

Aminoguanidine [CAS: 79-17-4], CH6N4, Mr 74.09, is a base that forms salts with both inorganic and organic acids. It is soluble in water and ethanol. Free aminoguanidine is stable for only a short time; therefore, it is marketed in the form of its stable salts. Commercially, aminoguanidine is offered as the bicarbonate salt [2582-30-1], a white powder of usually 99 % assay. The water solubility at room temperature is low (< 5 g/L). It is offered by most world-scale hydrazine producers (→Hydrazine). Other salts can be prepared from the bicarbonate by reaction with acid.

Uses

Inhibitor (advanced glycosylation end-product formation).

Definition

ChEBI: Aminoguanidine is a one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor and an EC 1.14.13.39 (nitric oxide synthase) inhibitor. It is a member of guanidines and a one-carbon compound.

Enzyme inhibitor

This substituted hydrazine (FWhydrochloride = 110.55 g/mol; CAS 79-17-4), also named pimagedine, is a strong inhibitor of diamine oxidases as well as nitric oxide synthase. Note that aminoguanidine also inhibits the formation of advanced glycosylation end-products, reportedly by reacting with and trapping Amadori rearrangement-derived fragmentation products in solution. In view of this property, aminoguanidine has often been used to treat complications associated with chronic diabetes. Target(s): amine oxidase (copper-containing), or diamine oxidase; methylamine dehydrogenase; tryptophan tryptophylquinone enzymes; nitric-oxide synthase; b-fructofuranosidase, or invertase; monoamine oxidase, or amine oxidase; histidine decarboxylase; aldose reductase; catalase; formation of advanced glycosylation end products; adenosylmethionine decarboxylase; arginine deaminase; arginine kinase; aspartate aminotransferase; histamine N-methyltransferase.

pimagedine Preparation Products And Raw materials

Raw materials

Preparation Products

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pimagedine Suppliers

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79-17-4, pimagedineRelated Search:

Nitroguanidine Aminoguanidinium nitrate 1,3-Diaminoguanidine monohydrochloride Aminoguanidinium Carbonate N'-Nitro-L-arginine 1-Methyl-3-nitro-1-nitrosoguanidine Z-ARG(NO2)-OH NITRON 2-HYDRAZINO-2-IMIDAZOLINE HYDROBROMIDE Nα-Boc-Nω-nitro-D-arginine 1-Methyl-3-nitroguanidine AMINOGUANIDINE HEMISULFATE GUANABENZ CHROMOTROPIC ACID DISODIUM SALT N'-NITRO-N-NITROSO-N-PROPYLGUANIDINE 1-BUTYL-3-NITRO-1-NITROSOGUANIDINE 1-(3-phenylpropylamino)guanidine hydrochloride METHYL GAG DIHYDROCHLORIDE

Ribavirin Impurity S

pimagedine

1-Aminoguanidine

Aminate base

Amino(imino)methylhydrazine

N-Aminoguanidine

Aids030897

Aids-030897

Aminoguanidine (ag)

Hydrazinecarboximidamide(9CI)

Aminoguanidine mordant

HYDRAZINECARBOXIMIDAMIDE (BASE)

Monoaminoguanidine

79-17-4

HNCNH2NHNH2H2CO3

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