2-methoxy-6-methylpyrazine

Product Name: 2-methoxy-6-methylpyrazine
CAS No.: 2882-21-5
Chemical Name: 2-methoxy-6-methylpyrazine
Synonyms: 2-methoxy-6-methylpyrazine;2-METHOXYL-6-METHYLPYRAZINE;Pyrazine, 2-methoxy-6-methyl-;2-methoxy-6-methyl pyrazine USP/EP/BP
CBNumber: CB5882737
Molecular Formula: C6H8N2O
Formula Weight: 124.14
MOL File: 2882-21-5.mol

More

Less

2-methoxy-6-methylpyrazine Property

Boiling point:: 48-50 °C(Press: 15 Torr)
Density: 1.068±0.06 g/cm3(Predicted)
FEMA: 3183 | 2,5 OR 6-METHOXY-3-METHYLPYRAZINE (MIXTURE OF ISOMERS)
pka: 1.32±0.10(Predicted)
Odor: at 0.10 % in propylene glycol. roasted hazelnut almond peanut
Odor Type: nutty
JECFA Number: 788
LogP: 1.21
EPA Substance Registry System: Pyrazine, 2-methoxy-6-methyl- (2882-21-5)

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: M336538
Product name: 2-Methoxy-6-methylpyrazine
Packaging: 500mg
Price: $300
Updated: 2021/12/16

AK Scientific

Product number: 2865AB
Product name: 2-Methoxy-6-methylpyrazine
Packaging: 1g
Price: $239
Updated: 2021/12/16

Ambeed

Product number: A178189
Product name: 2-Methoxy-6-methylpyrazine
Purity: 97%
Packaging: 100mg
Price: $130
Updated: 2021/12/16

Ambeed

Product number: A178189
Product name: 2-Methoxy-6-methylpyrazine
Purity: 97%
Packaging: 250mg
Price: $225
Updated: 2021/12/16

Chemenu

Product number: CM168036
Product name: 2-methoxy-6-methylpyrazine
Purity: 95%
Packaging: 5g
Price: $421
Updated: 2021/12/16

More

Less

2-methoxy-6-methylpyrazine Chemical Properties,Usage,Production

Chemical Properties

2 or 5 or 6-Methoxy-3-methylpyrazine has an aroma reminiscent of hazelnut, almond and peanut. The methyl methoxy pyrazines are used as nut-like flavoring agents for foods and beverages. The 2-methoxy-3-methyl derivative is used as a coffee aroma enhancing agent.

Occurrence

Reported found in sherry and krill.

Uses

2-Methoxy-6-methylpyrazine can be used for drug storage package storing antiviral and antibacterial.

Definition

ChEBI: 2-Methoxy-6-methylpyrazine is a member of pyrazines and an aromatic ether.

Preparation

From 2-methylpyrazine by various routes.

Aroma threshold values

Detection: 3 to 7 ppb

Synthesis

38557-71-0

2882-21-5

General procedure for the synthesis of 2-methoxy-6-methylpyrazine from 2-chloro-6-methylpyrazine: 2-chloro-6-methylpyrazine (24 g, 186.7 mmol) was suspended in anhydrous methanol (240 mL) under the protection of nitrogen followed by the addition of sodium methanolate (12.1 g, 224 mmol). The reaction mixture was stirred at 60-70°C for 16 hours. After completion of the reaction, the mixture was cooled to room temperature and filtered to remove insoluble material. The filtrate was concentrated under reduced pressure to give 2-methoxy-6-methylpyrazine (22 g, 95% yield). The product was characterized by 1H NMR (CDCl3, 400 MHz): δ 7.98 (s, 1H), 7.94 (s, 1H), 3.91 (s, 3H), 3.40 (s, 3H). LC-MS analysis showed a retention time tR = 1.47 min (Method 14) and a mass-to-charge ratio of m/z = 124.8 [M + H]+.

References

[1] Patent: WO2016/174188, 2016, A1. Location in patent: Page/Page column 47; 48

2-methoxy-6-methylpyrazine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-methoxy-6-methylpyrazine Suppliers

China 41 Germany 1 United Kingdom 2 United States 2 USA 1 Global 47

ChemShuttle, Inc.

Tel: 0510-83588313-811 18800520310
Email: sales@chemshuttle.com
Country: China
ProdList: 2999
Advantage: 62

Shanghai ZaiQi Bio-Tech Co., Ltd.

Tel: 021-54824098, 021-37212705 021-37212706, 13391256916
Fax: 021-54824069
Email: sales@chemzq.com
Country: China
ProdList: 570
Advantage: 55

Chiba Pharmaceutical Science and technology Co, Ltd.

Tel: 0531-81313138 13066006660
Fax: QQ: 3366077777
Email: chibapharm@foxmail.com
Country: China
ProdList: 3991
Advantage: 55

Chemfun Medical Technology(Shanghai) Co., Ltd.

Tel: 021-67220633 021-54824098
Fax: +86-21-54824069
Email: chemfun@chemfun.net
Country: China
ProdList: 491
Advantage: 58

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 0512-0512-52358471 17715136450
Fax: 05125235 6881
Email: sales@shiyabiopharm.com
Country: China
ProdList: 12127
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Sichuan BaiPeng Biotechnology Co., Ltd.

Tel: 028-65791793 18140026355
Fax: QQ568470422
Email: 568470422@qq.com
Country: China
ProdList: 9997
Advantage: 58

Shijiazhuang Jing Kang Technology Co.Ltd.

Tel: 13933818572
Fax: 0311-82870388
Email: 1519554262@qq.com
Country: China
ProdList: 1785
Advantage: 58

Aikon International Limited

Tel: 025-66061636 18013972705
Fax: (3)02557626880
Email: qqyang@aikonchem.com
Country: China
ProdList: 15814
Advantage: 58

Suzhou Nuoouman Biological Technology Co., Ltd.

Tel: 15026866316
Email: 180642609@qq.com
Country: China
ProdList: 4967
Advantage: 58

2882-21-5, 2-methoxy-6-methylpyrazineRelated Search:

Pyrazinecarbothioamide, 6-methoxy- (9CI) 2-METHYL-6-PROPOXYPYRAZINE 2-Methoxy-6-isopropylpyrazine METHYL6-METHOXY-2-PYRAZINECARBOXYLATE 6-Methoxy-pyrazinecarboxylicacid 2-ethoxy-6-methylpyrazine 2-methoxy-6-methylpyrazine 2-(3-bromophenoxy)-6-methylpyrazine 3-[(6-Methylpyrazin-2-yl)oxy]aniline 6-METHOXYPYRAZINECARBOXIMIDIC ACID METHYL ESTER SPECS AC-907/25005335 Pyrazine, 2-methoxy-6-(1-methylpropyl)- RARECHEM BG FB 0153 5,6-DIMETHOXY-2,3-PYRAZINEDICARBONITRILE RARECHEM BG FB 0010 RARECHEM BG FB 0152 RARECHEM BG FB 0154 5-(3,4-DIMETHOXYPHENYL)-3-METHOXY-2-PYRAZINECARBONITRILE

2-methoxy-6-methylpyrazine

Pyrazine, 2-methoxy-6-methyl-

2-METHOXYL-6-METHYLPYRAZINE

2-methoxy-6-methyl pyrazine USP/EP/BP

2882-21-5