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METHYL6-METHOXY-2-PYRAZINECARBOXYLATE

Product Name
METHYL6-METHOXY-2-PYRAZINECARBOXYLATE
CAS No.
23813-24-3
Chemical Name
METHYL6-METHOXY-2-PYRAZINECARBOXYLATE
Synonyms
6-Methoxy-2-Methoxycarbonylpyrazine;METHYL6-METHOXY-2-PYRAZINECARBOXYLATE;ethyl 6-methoxypyrazine-2-carboxylate;Methyl 6-Methoxypyrazine-2-carboxylate;6-Methoxypyrazine-2-carboxylic acid methyl ester;6-Methoxy-2-pyrazinecarboxylic acid methyl ester;2-Methoxy-6-pyrazinecarboxylic acid methyl ester;2-Pyrazinecarboxylic acid, 6-methoxy-, methyl ester
CBNumber
CB61111662
Molecular Formula
C7H8N2O3
Formula Weight
168.15
MOL File
23813-24-3.mol
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METHYL6-METHOXY-2-PYRAZINECARBOXYLATE Property

Melting point:
81.5-82℃
Boiling point:
249.9±35.0℃ (760 Torr)
Density 
1.220±0.06 g/cm3 (20 ºC 760 Torr)
Flash point:
105.0±25.9℃
storage temp. 
2-8°C
pka
-1.36±0.10(Predicted)
Appearance
Off-white to yellow Solid
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Safety

HS Code 
2933119000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
M223335
Product name
Methyl6-Methoxy-2-pyrazinecarboxylate
Packaging
10mg
Price
$45
Updated
2021/12/16
TRC
Product number
M223335
Product name
Methyl6-Methoxy-2-pyrazinecarboxylate
Packaging
100mg
Price
$240
Updated
2021/12/16
ChemScene
Product number
CS-0035570
Product name
Methyl6-methoxypyrazine-2-carboxylate
Purity
99.51%
Packaging
10g
Price
$313
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0078239
Product name
METHYL 6-METHOXY-2-PYRAZINECARBOXYLATE
Purity
95.00%
Packaging
1G
Price
$469.35
Updated
2021/12/16
Matrix Scientific
Product number
121969
Product name
Methyl6-methoxypyrazine-2-carboxylate
Purity
>95%
Packaging
1g
Price
$532
Updated
2021/12/16
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METHYL6-METHOXY-2-PYRAZINECARBOXYLATE Chemical Properties,Usage,Production

Synthesis

13924-99-7

23813-24-3

Example 68. General procedure for the synthesis of methyl 6-methoxy-2-pyrazinecarboxylate from 6-oxo-1,6-dihydropyrazine-2-carboxylic acid: 4 mL (0.030 mol) of trimethylsilyl chloride was added to 0.42 g (0.003 mol) of 6-hydroxypyrazine-2-carboxylic acid suspended in 10 mL of anhydrous methanol. The reaction mixture was stirred at room temperature for 48 h. A gradual transformation of the suspension into a clarified solution was observed. This method is suitable for the conversion of 6-hydroxypyrazine-2-carboxylic acid to the corresponding 6-alkoxypyrazine-2-carboxylic acid ester by selecting a suitable alcohol; if the alcohol used is non-liquid, an inert solvent, such as tetrahydrofuran (THF), can be used as the reaction medium. After completion of the reaction, the solvent and excess trimethylchlorosilane were removed by rotary evaporator under reduced pressure. The crude product was purified by silica gel column chromatography with gradient elution of hexane-ethyl acetate to give 0.11 g (22% yield) of the target product, methyl 6-methoxypyrazine-2-carboxylate.

References

[1] Patent: US5643912, 1997, A

METHYL6-METHOXY-2-PYRAZINECARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL6-METHOXY-2-PYRAZINECARBOXYLATE Suppliers

PharmaBlock Sciences (Nanjing),Inc.
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23813-24-3, METHYL6-METHOXY-2-PYRAZINECARBOXYLATERelated Search:


  • METHYL6-METHOXY-2-PYRAZINECARBOXYLATE
  • 2-Methoxy-6-pyrazinecarboxylic acid methyl ester
  • 6-Methoxy-2-pyrazinecarboxylic acid methyl ester
  • 6-Methoxypyrazine-2-carboxylic acid methyl ester
  • 6-Methoxy-2-Methoxycarbonylpyrazine
  • Methyl 6-Methoxypyrazine-2-carboxylate
  • ethyl 6-methoxypyrazine-2-carboxylate
  • 2-Pyrazinecarboxylic acid, 6-methoxy-, methyl ester
  • 23813-24-3