ChemicalBook > CAS DataBase List > 2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one

2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one

Product Name
2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one
CAS No.
20348-21-4
Chemical Name
2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one
Synonyms
Einecs 243-753-2;2,2-Dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H);2,2-dimethyl-4H-pyrido[2,3-e][1,4]oxazin-3-one;2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one;2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one;2,2-DIMETHYL-2H-PYRIDO(3,2-B)(1,4)OXAZINE-3(4H)-ONE;2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 2,2-diMethyl-;2,2-diMethyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one
CBNumber
CB5909443
Molecular Formula
C9H10N2O2
Formula Weight
178.19
MOL File
20348-21-4.mol
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2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one Property

Boiling point:
352.5±37.0 °C(Predicted)
Density 
1.176±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 
Store at room temperature
pka
11.13±0.40(Predicted)
form 
solid
Appearance
White to off-white Solid
InChI
InChI=1S/C9H10N2O2/c1-9(2)8(12)11-7-6(13-9)4-3-5-10-7/h3-5H,1-2H3,(H,10,11,12)
InChIKey
DMLNXUUGRSBBBR-UHFFFAOYSA-N
SMILES
O1C(C)(C)C(=O)NC2=NC=CC=C12
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Safety

HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHB00083
Product name
2,2-Dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
Purity
AldrichCPR
Packaging
1G
Price
$201
Updated
2023/06/20
TRC
Product number
D479888
Product name
2,2-Dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
Packaging
50mg
Price
$45
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-1-MB
Product name
2,2-Dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
Packaging
1g
Price
$75
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD126905
Product name
2,2-Dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
Packaging
250mg
Price
$85
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD126905
Product name
2,2-Dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
Packaging
500mg
Price
$150
Updated
2021/12/16
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2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one Chemical Properties,Usage,Production

Synthesis

16867-03-1

600-00-0

20348-21-4

Step - (i): Synthesis of 2,2-dimethyl-2H-pyrido[3,2-B][1,4]oxazin-3(4H)-one (18.1) 2-Amino-3-hydroxypyridine (5 g, 45.45 mmol) was dissolved in acetone (50 mL) at 20-35 °C and stirred to form a solution. Subsequently K2CO3 (25.09g, 181.81mmol) was added followed by dropwise addition of ethyl 2-bromo-2-methylpropionate (13.29g, 68.18mmol). The reaction mixture was stirred at 70 °C for 16 hours. After completion of the reaction, the mixture was cooled to 20-35 °C and diluted with ice water. The resulting solid was collected by filtration and washed with water to afford the target compound as a white solid (5g, 97% yield). 1H NMR (400MHz, DMSO-d6): [specific NMR data should be added here].

References

[1] Patent: WO2015/71780, 2015, A1. Location in patent: Page/Page column 22
[2] Tetrahedron Letters, 2010, vol. 51, # 14, p. 1852 - 1855
[3] Acta Chemica Scandinavica (1947-1973), 1969, vol. 23, p. 2322 - 2324

2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one manufacturers

Shanghai Rlavie Technology Co ltd
Product
2,2-dimethyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one 20348-21-4
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
100kgs/month
Release date
2021-11-20
Career Henan Chemical Co
Product
2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one 20348-21-4
Price
US $0.00/KG
Min. Order
1KG
Purity
90%-99.9%
Supply Ability
500kg
Release date
2019-07-05

20348-21-4, 2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-oneRelated Search:

2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one 2-METHYL-N-(3-MORPHOLINOPROPYL)-3-OXO-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZINE-2-CARBOXAMIDE 6-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE 2,2-DIMETHYL-6-NITRO-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE 7-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE 2-METHYL-3-OXO-N-(TETRAHYDRO-2-FURANYLMETHYL)-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZINE-2-CARBOXAMIDE 2-METHYL-3-OXO-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZINE-2-CARBOXYLIC ACID ETHYL 2-METHYL-3-OXO-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZINE-2-CARBOXYLATE 2,2-DIMETHYL-7-NITRO-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE N-(3,4-DICHLOROBENZYL)-2-METHYL-3-OXO-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZINE-2-CARBOXAMIDE N-(2-METHOXYBENZYL)-2-METHYL-3-OXO-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZINE-2-CARBOXAMIDE

  • 2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one
  • Einecs 243-753-2
  • 2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one
  • 2,2-diMethyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one
  • 2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 2,2-diMethyl-
  • 2,2-dimethyl-4H-pyrido[2,3-e][1,4]oxazin-3-one
  • 2,2-Dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)
  • 2,2-DIMETHYL-2H-PYRIDO(3,2-B)(1,4)OXAZINE-3(4H)-ONE
  • 20348-21-4