N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride
- Product Name
- N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride
- CAS No.
- 4784-40-1
- Chemical Name
- N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride
- Synonyms
- Ao Suoma hydrochloride;Oxomemazine hydrochloride;Oxomemazine·hydrochloric acid;N,N,β-Trimethyl-[10H]-phenothiazine-10-propanamine 5,5-dioxide hydrochloride;10-(3-(dimethylamino)-2-methylpropyl)-10H-phenothiazine 5,5-dioxide hydrochloride;N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride
- CBNumber
- CB5925092
- Molecular Formula
- C18H23ClN2O2S
- Formula Weight
- 366.9
- MOL File
- 4784-40-1.mol
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- API0009065
- Product name
- METHDILAZINE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 50MG
- Price
- $697.34
- Updated
- 2021/12/16
- Product number
- API0009065
- Product name
- METHDILAZINE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 500MG
- Price
- $1758.49
- Updated
- 2021/12/16
- Product number
- API0009065
- Product name
- METHDILAZINE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $2355.15
- Updated
- 2021/12/16
N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride Chemical Properties,Usage,Production
Originator
Doxergan,Specia,France,1964
Manufacturing Process
Phenothiazine is reacted with 3-dimethylamino-2-methylpropyl chloride in the presence of sodium amide to give 3-(10-phenthiazinyl)-2-methyl-1dimethylaminopropane. 11.9 g of of this intermediate is dissolved with agitation in glacial acetic acid (120 cc). Pure sulfuric acid (d = 1.83; 0.5 cc) is added and a mixture of glacial acetic acid (10 cc) and hydrogen peroxide (8.5 cc of a solution containing 38 g of hydrogen peroxide in 100 cc) is then run in over 20 minutes. The temperature rises from 25°C to 35°C and is then kept at 60°C for 18 hours. The mixture is cooled and water (150 cc) is added and, with cooling, aqueous sodium hydroxide (d = 1.33; 220 cc). The resulting
mixture is extracted with ethyl acetate (3 x 100 cc), the solvent is evaporated on a water bath and the residue is recrystallized from heptane (150 cc). 3(9,9-dioxy-10-phenthiazinyl)-2-methyl-1-dimethylaminopropane (78 g) is obtained, MP 115°C.
The corresponding hydrochloride prepared in ethyl acetate and recrystallized from a mixture of ethanol and isopropanol melts at 250°C.
Therapeutic Function
Antihistaminic
N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride manufacturers
- Product
- N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride 4784-40-1
- Price
- US $6780.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1-100kg
- Release date
- 2021-06-04
- Product
- N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride 4784-40-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- N,N,beta-trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride 4784-40-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08