ChemicalBook > CAS DataBase List > 1H-indole-3-propylamine
1H-indole-3-propylamine
Synthesis- Product Name
- 1H-indole-3-propylamine
- CAS No.
- 6245-89-2
- Chemical Name
- 1H-indole-3-propylamine
- Synonyms
- Einecs 228-361-1;1H-indole-3-propylamine;1H-Indole-3-propanamine;N-propyl-1H-indol-3-amine;1H-Indole-3-propan-1-amine;(1H-Indol-3-yl)-1-propanamine
- CBNumber
- CB5927122
- Molecular Formula
- C11H14N2
- Formula Weight
- 174.24
- MOL File
- 6245-89-2.mol
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1H-indole-3-propylamine Property
- Melting point:
- 64 °C
- Boiling point:
- 353.7±25.0 °C(Predicted)
- Density
- 1.125±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 17.29±0.30(Predicted)
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Safety
- Risk Statements
- 20/21/22-37/38-48
- Safety Statements
- 22-26-7/8-36/37/39-45
- HS Code
- 29339900
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
TRC
- Product number
- I633913
- Product name
- 3-(Indol-3-yl)propanamine
- Packaging
- 50mg
- Price
- $95
- Updated
- 2021/12/16
TRC
- Product number
- I633913
- Product name
- 3-(Indol-3-yl)propanamine
- Packaging
- 250mg
- Price
- $250
- Updated
- 2021/12/16
AK Scientific
- Product number
- J55003
- Product name
- (1H-Indol-3-yl)-1-propanamine
- Packaging
- 1g
- Price
- $135
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 072031
- Product name
- (1H-Indol-3-yl)-1-propanamine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $440
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0074502
- Product name
- 3-(1H-INDOL-3-YL)-1-PROPANAMINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $925.31
- Updated
- 2021/12/16
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1H-indole-3-propylamine Chemical Properties,Usage,Production
Synthesis
A solution of LAH (1.0 M in ether, 36.5 mL, 36.5 mmol) was cooled to 0 °C, and a solution of the cyanoethyl indole (2.78 g, 16.3 mmol) was added slowly. Then, the solution was heated at reflflux for 3 h. It was cooled to 0 °C and quenched by dropwise addition of water (20 mL) followed by 1 N sodium hydroxide (40 mL). The phases were separated, and the aqueous phase was extracted with ether. The combined organic phases were washed with brine and then dried (potassium hydroxide). Evaporation of the solvent gave 2.6 g (92%) of homotryptamine as a yellow oil, which solidifified on standing. The hydrochloride was prepared by dissolving the amine in a minimum of ethanol and then a saturated solution of hydrogen chloride in ether was added until no additional salt formation was observed. The hydrochloride was recrystallized from ethanol.
Reference: Kuehne, M. E.; Cowen, S. D.; Xu, F.; Borman, L. S. J. Org. Chem. 2001, 66, 5303–5316.
Chemical Properties
Light yellow powder
1H-indole-3-propylamine Preparation Products And Raw materials
Raw materials
Preparation Products
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