1-(4-hydroxyphenyl)-2-methoxyethan-1-one

Product Name: 1-(4-hydroxyphenyl)-2-methoxyethan-1-one
CAS No.: 32136-81-5
Chemical Name: 1-(4-hydroxyphenyl)-2-methoxyethan-1-one
Synonyms: 2-Methoxy-4'-hydroxyacetophenone;Alpha Methoxy -4-Hydroxy acetophenone;2-Methoxy-1-(4-hydroxyphenyl)ethanone;1-(4-Hydroxyphenyl)-2-methoxyethanone;1-(4-hydroxyphenyl)-2-methoxyethan-1-one;Ethanone, 1-(4-hydroxyphenyl)-2-methoxy-;2-Butenoicacid,2-hydroxy-4-[3-methyl-4-(phenylmethoxy)phenyl]-4-oxo-,methylester,(4Z)-
CBNumber: CB5930272
Molecular Formula: C9H10O3
Formula Weight: 166.17
MOL File: 32136-81-5.mol

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1-(4-hydroxyphenyl)-2-methoxyethan-1-one Property

Melting point:: 128-130°C
Boiling point:: 315.6±22.0 °C(Predicted)
Density: 1.168±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: Acetone (Slightly), Methanol (Slightly)
form: Solid
pka: 7.84±0.15(Predicted)
color: Light Orange to Light Brown
InChI: InChI=1S/C9H10O3/c1-12-6-9(11)7-2-4-8(10)5-3-7/h2-5,10H,6H2,1H3
InChIKey: HUXGFSJRCMJOAK-UHFFFAOYSA-N
SMILES: C(=O)(C1=CC=C(O)C=C1)COC

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Safety

HS Code: 2914500090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M262600
Product name: 2-Methoxy-4''-hydroxyacetophenone
Packaging: 250mg
Price: $110
Updated: 2021/12/16

TRC

Product number: M262600
Product name: 2-Methoxy-4''-hydroxyacetophenone
Packaging: 2.5g
Price: $875
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0378055
Product name: 1-(4-HYDROXYPHENYL)-2-METHOXYETHANONE
Purity: 95.00%
Packaging: 5MG
Price: $505.59
Updated: 2021/12/16

Abosyn

Product number: 61-3394
Product name: 1-(4-Hydroxyphenyl)-2-methoxyethanone
Purity: 95%-98%
Packaging: 5g
Price: $375
Updated: 2021/12/16

Crysdot

Product number: CD12083994
Product name: 1-(4-Hydroxyphenyl)-2-methoxyethanone
Purity: 98%
Packaging: 5g
Price: $386
Updated: 2021/12/16

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1-(4-hydroxyphenyl)-2-methoxyethan-1-one Chemical Properties,Usage,Production

Chemical Properties

Tan Solid

Uses

2-Methoxy-4''-hydroxyacetophenone (cas# 32136-81-5) is a compound useful in organic synthesis.

Preparation

Obtained by scission of 5-hydroxy-4-(4-hydroxyphenyl) 5H-furan-2-one with potassium hydroxide in methanol at 20° for 24 h (85%). – Also obtained by catalytic debenzylation of 1-(4-benzyloxyphenyl)-2-methoxyethanone in methanol under hydrogen (five bars) in the presence of 5% Pd/C for 24 h (81%).

Synthesis

2491-38-5

32136-81-5

General procedure for the synthesis of 1-(4-hydroxyphenyl)-2-methoxyacetophenone from 2-bromo-1-(4-hydroxyphenyl)acetophenone: Example 3 Preparation of α-methoxy-4-hydroxyacetophenone. Dissolve 2 g of α-bromo-4-hydroxyacetophenone in 11 g of methanol. 30g of methanol solution of saturated sodium hydroxide (1g NaOH dissolved in 4.2ml methanol) was slowly added dropwise to the above solution. Upon completion of the dropwise addition, the reaction mixture was poured into 30 g of ice water and the pH was adjusted with acid to 6. Subsequently, α-methoxy-4-hydroxyacetophenone precipitated as a precipitate, and after filtration and drying, a yellowish-green product was obtained in about 85% yield. The purity of the product was confirmed by 1H-NMR analysis.

References

[1] Patent: US5107034, 1992, A

1-(4-hydroxyphenyl)-2-methoxyethan-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(4-hydroxyphenyl)-2-methoxyethan-1-one Suppliers

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32136-81-5, 1-(4-hydroxyphenyl)-2-methoxyethan-1-oneRelated Search:

4'-(4-CHLOROPHENYL)-2,2':6',2''-TERPYRIDINE 4'-PHENYL-2,2':6',2''-TERPYRIDINE 4'-(4-iodophenyl)-2,2':6',2''-Terpyridine 4'-(4-BROMOPHENYL)-2,2':6',2''-TERPYRIDINE

1-(4-hydroxyphenyl)-2-methoxyethan-1-one

1-(4-Hydroxyphenyl)-2-methoxyethanone

2-Methoxy-1-(4-hydroxyphenyl)ethanone

2-Methoxy-4'-hydroxyacetophenone

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Alpha Methoxy -4-Hydroxy acetophenone

32136-81-5

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