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azafenidin

Product Name
azafenidin
CAS No.
68049-83-2
Chemical Name
azafenidin
Synonyms
C10895;R 6447;Evolus;Milestone;IN-R 6447;DPX-R 6447;azafenidin;2-(2,4-dichloro-5-prop-2-ynyloxyphenyl)-5,6,7,8-tetrahydro-1,2,4-triazole(4,3-a)pyridin-3(2H)-one;2-(2,4-dichloro-5-prop-2-ynyloxypnenyl)-5,6,7,8-tetrahy-dro-1,2,4-trizolo [4,3-α] pyridin-3-(2H)-one;1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[2,4-dichloro-5-(2-propyn-1-yloxy)phenyl]-5,6,7,8-tetrahydro-
CBNumber
CB5945861
Molecular Formula
C15H13Cl2N3O2
Formula Weight
338.19
MOL File
68049-83-2.mol
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azafenidin Property

Melting point:
168-168.5°
Boiling point:
468.9±55.0 °C(Predicted)
Density 
1.43±0.1 g/cm3(Predicted)
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
2.45±0.20(Predicted)
color 
Brown to Dark Brown
EPA Substance Registry System
Azafeniden (68049-83-2)
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Safety

Hazard Codes 
T,N
Risk Statements 
61-48/22-62-50/53
Safety Statements 
53-45-60-61
Toxicity
LD50 in rats, mice, bobwhite quail, mallard duck (mg/kg): >5000, >5000, >2500, >2500 orally; in rabbits (mg/kg): >2000 dermally.; LC50 in rats, rainbow trout, blue gill sunfish (mg/l): >5.3, 33, 48 (Amuti)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P314Get medical advice/attention if you feel unwell.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
A797400
Product name
Azafenidin
Packaging
0.5mg
Price
$195
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AGR0000375
Product name
AZAFENIDIN
Purity
95.00%
Packaging
5MG
Price
$496.14
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
38782
Product name
Azafenidin
Packaging
5mg
Price
$990
Updated
2021/12/16
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azafenidin Chemical Properties,Usage,Production

Uses

Azafenidin is a weed controlling herbicide used in various crops.

Uses

Herbicide.

Definition

ChEBI: Azafenidin is a triazolopyridine that is 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one which is substituted at position 2 by a 2,4-dichloro-5-(prop-2-yn-1-yloxy)phenyl group. A protoporphyrinogen oxidase inhibitor, it is used as a herbicide to control weeds in fruit crops such as pineapple, citrus, melons, and grapes. Not approved for use within the European Union. It has a role as an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor. It is a triazolopyridine, a terminal acetylenic compound and a dichlorobenzene.

Metabolic pathway

A common degradation reaction of azafenidin in light, plants and soil is O-dealkylation, and interesting minor reactions in soil are the subsequent methylation of the O-dealkylated degradation product and the reduction of the propynyl group under anaerobic conditions. In soil and light, azafenidin is also readily split to form the triazolinone heterocycle. Azafenidin is readily metabolized in rats and lactating goats through O-dealkylation, hydroxylation of the triazolinone ring in several positions, and glucuronide and sulfate conjugation.

azafenidin Preparation Products And Raw materials

Raw materials

Preparation Products

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azafenidin Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
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Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8065
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58
Shenzhen SUNGENING Bio-Medical Co., Ltd.
Tel
0755-28967200 13631290199
Fax
0755-28967200
Email
wxf@sungening.com
Country
China
ProdList
9577
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57412
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58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
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Huansheng Meisen Pharmaceutical Technology (Shandong) Co., Ltd
Tel
0531-88762217 18301471076
Email
sales@acespharma.com
Country
China
ProdList
3863
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
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58
Shandong Mopai Biotechnology Co., Ltd
Tel
13070690626
Email
admin@mopaikeji.com
Country
China
ProdList
10756
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Nantong Zhonghe Chemical New Materials Co., Ltd
Tel
13003551299 13003551299
Email
2369399482@qq.com
Country
China
ProdList
7566
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58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
17301488900
Fax
025-85560043
Email
judy.xia@synzest.com
Country
China
ProdList
12582
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58

68049-83-2, azafenidinRelated Search:


  • 2-(2,4-dichloro-5-prop-2-ynyloxyphenyl)-5,6,7,8-tetrahydro-1,2,4-triazole(4,3-a)pyridin-3(2H)-one
  • azafenidin
  • Evolus
  • Milestone
  • 2-(2,4-dichloro-5-prop-2-ynyloxypnenyl)-5,6,7,8-tetrahy-dro-1,2,4-trizolo [4,3-α] pyridin-3-(2H)-one
  • DPX-R 6447
  • IN-R 6447
  • R 6447
  • C10895
  • 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[2,4-dichloro-5-(2-propyn-1-yloxy)phenyl]-5,6,7,8-tetrahydro-
  • 68049-83-2
  • Agro-Products, Aromatics, Heterocycles