azafenidin
- Product Name
- azafenidin
- CAS No.
- 68049-83-2
- Chemical Name
- azafenidin
- Synonyms
- C10895;R 6447;Evolus;Milestone;IN-R 6447;DPX-R 6447;azafenidin;2-(2,4-dichloro-5-prop-2-ynyloxyphenyl)-5,6,7,8-tetrahydro-1,2,4-triazole(4,3-a)pyridin-3(2H)-one;2-(2,4-dichloro-5-prop-2-ynyloxypnenyl)-5,6,7,8-tetrahy-dro-1,2,4-trizolo [4,3-α] pyridin-3-(2H)-one;1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[2,4-dichloro-5-(2-propyn-1-yloxy)phenyl]-5,6,7,8-tetrahydro-
- CBNumber
- CB5945861
- Molecular Formula
- C15H13Cl2N3O2
- Formula Weight
- 338.19
- MOL File
- 68049-83-2.mol
azafenidin Property
- Melting point:
- 168-168.5°
- Boiling point:
- 468.9±55.0 °C(Predicted)
- Density
- 1.43±0.1 g/cm3(Predicted)
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 2.45±0.20(Predicted)
- color
- Brown to Dark Brown
- EPA Substance Registry System
- Azafeniden (68049-83-2)
Safety
- Hazard Codes
- T,N
- Risk Statements
- 61-48/22-62-50/53
- Safety Statements
- 53-45-60-61
- Toxicity
- LD50 in rats, mice, bobwhite quail, mallard duck (mg/kg): >5000, >5000, >2500, >2500 orally; in rabbits (mg/kg): >2000 dermally.; LC50 in rats, rainbow trout, blue gill sunfish (mg/l): >5.3, 33, 48 (Amuti)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H373May cause damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P273Avoid release to the environment.
P314Get medical advice/attention if you feel unwell.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A797400
- Product name
- Azafenidin
- Packaging
- 0.5mg
- Price
- $195
- Updated
- 2021/12/16
- Product number
- AGR0000375
- Product name
- AZAFENIDIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.14
- Updated
- 2021/12/16
- Product number
- 38782
- Product name
- Azafenidin
- Packaging
- 5mg
- Price
- $990
- Updated
- 2021/12/16
azafenidin Chemical Properties,Usage,Production
Uses
Azafenidin is a weed controlling herbicide used in various crops.
Uses
Herbicide.
Definition
ChEBI: Azafenidin is a triazolopyridine that is 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one which is substituted at position 2 by a 2,4-dichloro-5-(prop-2-yn-1-yloxy)phenyl group. A protoporphyrinogen oxidase inhibitor, it is used as a herbicide to control weeds in fruit crops such as pineapple, citrus, melons, and grapes. Not approved for use within the European Union. It has a role as an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor. It is a triazolopyridine, a terminal acetylenic compound and a dichlorobenzene.
Metabolic pathway
A common degradation reaction of azafenidin in light, plants and soil is O-dealkylation, and interesting minor reactions in soil are the subsequent methylation of the O-dealkylated degradation product and the reduction of the propynyl group under anaerobic conditions. In soil and light, azafenidin is also readily split to form the triazolinone heterocycle. Azafenidin is readily metabolized in rats and lactating goats through O-dealkylation, hydroxylation of the triazolinone ring in several positions, and glucuronide and sulfate conjugation.