(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane

Product Name: (2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane
CAS No.: 119302-24-8
Chemical Name: (2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane
Synonyms: LK-8;Rocuronium EP Impurity A;Rocuronium intermediate 8;RocuroniuM interMediate D;Rocuronium Bromide Impurity I;Rocuronium bromide EP Impurity A;Rocuronium Bromide Intermediate 8;Rocuronium Bromide Intermediate 2;Rocuronium USP Related Compound A;RocuroniuM BroMide InterMediate VIII
CBNumber: CB5950399
Molecular Formula: C29H48N2O4
Formula Weight: 488.7
MOL File: 119302-24-8.mol

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(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane Property

Melting point:: 152-156°C
Boiling point:: 574.1±50.0 °C(Predicted)
Density: 1.17
vapor pressure: 0Pa at 25℃
storage temp.: 2-8°C
solubility: Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
form: Solid
pka: 14.85±0.70(Predicted)
color: White to Light Brown
LogP: 3.9 at 22℃ and pH12

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC

Product number: A165650
Product name: (2β,3α,5α,16β,17β)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane
Packaging: 100mg
Price: $175
Updated: 2021/12/16

Matrix Scientific

Product number: 092388
Product name: (2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane
Purity: 95+%
Packaging: 250mg
Price: $591
Updated: 2021/12/16

Matrix Scientific

Product number: 092388
Product name: (2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane
Purity: 95+%
Packaging: 1g
Price: $1311
Updated: 2021/12/16

AK Scientific

Product number: O155
Product name: 2beta-(4-Morpholinyl)-16beta-(1-pyrrolidinyl)-5alpha-androstane-3alpha,17beta-diol17-acetate
Packaging: 1g
Price: $1819
Updated: 2021/12/16

AccelPharmtech

Product number: FB1397100G
Product name: (2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane
Purity: 98.00%
Packaging: 100G
Price: $18200
Updated: 2021/12/16

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(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane Chemical Properties,Usage,Production

Uses

(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane is used in the synthesis of the neuromuscular blocking agent rocuronium bromide.

(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane Preparation Products And Raw materials

Raw materials

Preparation Products

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(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane Suppliers

Canada 1 China 146 India 7 United States 8 Global 162

Shanghai Bioman Pharma Limited

Tel: 21-33738120 15000110506
Fax: 021-23025272
Email: info@bioman.com.cn
Country: China
ProdList: 61
Advantage: 62

Suzhou Huaxin Pharmaceutical Technology Co., Ltd.

Tel: 0512-67260010 13773004275
Email: vic.xu@hx-pharma.com
Country: China
ProdList: 19
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J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
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JinYan Chemicals(ShangHai) Co.,Ltd.

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Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
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Chemsky（shanghai）International Co.,Ltd.

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XiaoGan ShenYuan ChemPharm co,ltd

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China Langchem Inc.

Tel: 0086-21-58956006
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Beijing HuaMeiHuLiBiological Chemical

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Beijing Comparison Pharmaceutical Technology Co., Ltd

Tel: 010-52878169 15701683040
Email: sales@bjcomparison.com
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SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD.

Tel: 021-34666753 13311639313
Fax: +86-21-34979012
Email: info@shyrchem.com
Country: China
ProdList: 570
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View Lastest Price from (2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane manufacturers

Longyan Tianhua Biological Technology Co., Ltd

Product: 2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane 119302-24-8
Price: US $65.00/KG
Min. Order: 1KG
Purity: 99
Supply Ability: 1000KG
Release date: 2020-11-12

Career Henan Chemical Co

Product: (2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane 119302-24-8
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: 10kg
Release date: 2018-12-18

119302-24-8, (2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstaneRelated Search:

Moroxydine hydrochloride Rocuronium bromide (2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol 2-Pyrrolidinyl-3-acetyl Desmorpholinylrocuronium Bromide (5S,8R,9S,10S,13S,14S)-10,13-dimethyl-1,5,6,7,8,9,10,11,12,13,15,16-dodecahydro-4H-cyclopenta[a]phenanthren-17(14H)-one RocuroniuM BroMide IMpurity 15 Tridemorph Dimethomorph CHLOROPHOSPHONAZO III Moroxydine 5a-Androstane-3a,17b-diol rocuronium N-CETYLMORPHOLINE (2β,3α,5α,16β,17β)-17-Acetoxy-3-hydroxy-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane Acetoxy

2-β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5a-androstan-3a,17β-diol-17-acetate

(2B,3A,5A,16B,17B)-17-ACETOXY-3-HYDROXY-2-(4-MORPHOLINYL)-16-(1-PYRROLIDINYL)ANDROSTANE

（2，3，5，16，17）-17-acetoxy-3-hydroxy-2-（4-morpholinyl）-16-（1-pyrrolidinyl）androstane

(2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)-androstane-3,17-diol 17-acetate

2β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5α-androstane-3α,17β-diol 17-acetate

2beta-(4-Morpholinyl)-16beta-(1-pyrrolidinyl)-5alpha-androstane-3alpha,17beta-diol 17-acetate

(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane (2b,3a,5a,16b,17b)-1

RocuroniuM BroMide InterMediate VIII

(1R,2S,10R,11S,15S)-5-hydroxy-2,15-diMethyl-4-(Morpholin-4-yl)-13-(pyrrolidin-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl acetate

LK-8

RocuroniuM Related CoMpound A (EP iMpurity A)

Androstane-3,17-diol, 2-(4- Morpholinyl)-16-(1-pyrrolidinyl)-, 17-acetate,(2β,3α,5α,16β, 17β)-

RocuroniuM interMediate D

Rocuronium Bromide Impurity I

(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)

Rocuronium Bromide Intermediate 8

Rocuronium bromide intermeidate (LK-8)

3α-hydroxy-2β-(morpholin-4-yl)-16β-(pyrrolidin-1-yl)-5α-androstan-17β-yl acetate

2SS-(4-MORPHOLINYL)-16SS-(1-PYRROLIDINYL)-5A-ANDROSTANE-3A,17SS-DIOL 17-ACETATE

(2b,3a,5a,16b,17b)-17-acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane(9CI)

Rocuronium bromide EP Impurity A

Rocuronium intermediate 8

acetic acid [3-hydroxy-10,13-dimethyl-2-(4-morpholinyl)-16-(1-pyrrolidinyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl] ester

Rocuronium EP Impurity A

Rocuronium Bromide Impurity 1（Rocuronium Bromide EP Impurity A）

(2β,3α,5α,16β,17β)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane

Rocuronium Bromide Impurity 1（Rocuronium Bromide EP Impurity A）（ Rocuronium Bromide USP RC A）

Rocuronium Bromide Intermediate 2

(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16...

Rocuronium Bromide Impurity I (3α-hydroxy-2β -(morpholin-4-yl)-16β -(pyrrolidin-1-yl)-5α -androstan-17β-yl acetate)

Rocuronium USP Related Compound A

3α-hydroxy-2β-(morpholin-4-yl)-16β-(pyrrolidin-1-yl)- 5α-androstan-17β-yl acetate

(2b,3a,5a,16b,17b)-17- acetoxy -3- hydroxy -2-(4- morpholino) -16-(1- pyrrolidinyl) androstane

(2b, 3a, 5a, 16b, 17b) -17-acetoxy-3-hydroxy-2- (4-morpholino) -16- (1-pyrrolidyl) androstane

（4-morpholinyl）-16-(1-pyrryl)-Androstane-3-hydroxy-17- acetyl

119302-24-8

C29H48N2O4

4887

Intermediates