ChemicalBook > CAS DataBase List > ETIROXATE
ETIROXATE
- Product Name
- ETIROXATE
- CAS No.
- 17365-01-4
- Chemical Name
- ETIROXATE
- Synonyms
- CG-63;CG-635;ETIROXATE;DL-a-Methyl-thyroxine Ethyl Ester;DL-α-Methyl-thyroxine Ethyl Ester;Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-α-methyl-, ethyl ester;O-(4-Hydroxy-3,5-diiodo-phenyl)-3,5-diiodo-α-methyl-DL-tyrosine Ethyl Ester;O-(4-Hydroxy-3,5-diiodo-phenyl)-3,5-diiodo-a-methyl-DL-tyrosine Ethyl Ester;(±)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-2-methylpropionic acid ethyl ester
- CBNumber
- CB5985045
- Molecular Formula
- C18H17I4NO4
- Formula Weight
- 818.935
- MOL File
- 17365-01-4.mol
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ETIROXATE Property
- Melting point:
- 149-1510C
- Boiling point:
- 563.7±50.0 °C(Predicted)
- Density
- 2.321±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- DMSO, Methanol
- form
- Solid
- pka
- 6.89±0.25(Predicted)
- color
- Tan
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N-Bromosuccinimide Price
TRC
- Product number
- E932980
- Product name
- Etiroxate
- Packaging
- 5mg
- Price
- $90
- Updated
- 2021/12/16
TRC
- Product number
- E932980
- Product name
- Etiroxate
- Packaging
- 10mg
- Price
- $110
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0000557
- Product name
- ETIROXATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $311.3
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0000557
- Product name
- ETIROXATE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $704.55
- Updated
- 2021/12/16
Medical Isotopes, Inc.
- Product number
- 10176
- Product name
- Etiroxate
- Packaging
- 10mg
- Price
- $860
- Updated
- 2021/12/16
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ETIROXATE Chemical Properties,Usage,Production
Chemical Properties
Tan Solid
Originator
Skleronorm,Gruenenthal,W. Germany,1977
Uses
Derivative of thyroxine. Antilipemic.
Definition
ChEBI: Etiroxate is an aromatic ether.
Manufacturing Process
7.91 g of α-methyl thyroxine are suspended in 150 cc of ethanol. While heating, the solution is saturated with dry hydrogen chloride. Thereafter, the solvent is distilled off at reduced pressure. The residue is dissolved in a mixture of ethanol and water (1:1). Adding a 5% solution of sodium hydrogen carbonate in water, the ethyl ester of α-methyl thyroxine precipitates; melting point: 156°C to 157°C after recrystallization from ethanol. The yield is 6.05 g, i.e., 74% of the theoretical yield.
Therapeutic Function
Antihyperlipoproteinemic
ETIROXATE Preparation Products And Raw materials
Raw materials
Preparation Products
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ETIROXATE Suppliers
17365-01-4, ETIROXATERelated Search:
2-Amino-2-methyl-propionic acid ethyl ester hydrochloride
3,5-DIIODO-DL-THYRONINE
1-METHOXY-3,5-DIIODOBENZENE
ETHYL (S)-2-AMINO-2-METHYLBUTYRATE
3,3',5-TRIIODOTHYROPROPIONIC ACID
3 5-DIIODOTHYROPROPIONIC ACID
DL-ALPHA-METHYLTYROSINE
DL-THYROXINE
2 6-DIIODOHYDROQUINONE
ETIROXATE